GSE85027[Accession] - GEO DataSets

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Items: 5

Select item 2000850271.

Dido as a switchboard that regulates self-renewal and differentiation in embryonic stem cells (vsmutNT)

(Submitter supplied) Transition from symmetric to asymmetric cell division requires precise coordination of differential gene expression. Embryonic stem cells (ESC) strongly express Dido3, whose C-terminal truncation impedes ESC differentiation while retaining self-renewal. We show that Dido3 binds to its gene locus via H3K4me3 and RNA pol II and, at differentiation onset, induces expression of its splice variant Dido1, which then leads to Dido3 degradation and downregulation of stemness genes. more...

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL10333
3 Samples

Download data: TXT

Series

Accession:: GSE85027

ID:: 200085027

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 1000103332.

Agilent-026655 Whole Mouse Genome Microarray 4x44K v2 (Feature Number version)

(Submitter supplied) Mouse Content Refresh 44k Arrays of this design have barcodes that begin with 16026655 or 2526655. Orientation: Features are numbered numbered Left-to-Right, Top-to-Bottom as scanned by an Agilent scanner (barcode on the left, DNA on the back surface, scanned through the glass), matching the FeatureNum output from Agilent's Feature Extraction software. The ID column represents the Agilent Feature Extraction feature number. more...