GSE81969[Accession] - GEO DataSets - NCBI

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Items: 10

Select item 2000819691.

Mapping H4K20me3 onto the chromatin landscape of senescent cells indicates a function in control of cell senescence and tumor suppression through preservation of genetic and epigenetic stability.

(Submitter supplied) Histone modification H4K20me3 and its methyltransferase SUV420H2 have been implicated in suppression of tumorigenesis. The underlying mechanism is unclear, although abundance of H4K20me3 increases during cellular senescence. Cellular senescence is a stable proliferation arrest and tumor suppressor process, triggered by diverse molecular cues, including activated oncogenes. Here, we set out to better understand the function of H4K20me3 in senescence and tumor suppression.

Organism:: Homo sapiens

Type:: Genome binding/occupancy profiling by high throughput sequencing

Platform:: GPL18573
8 Samples

Download data: BED

Series

Accession:: GSE81969

ID:: 200081969

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 1000185732.

Illumina NextSeq 500 (Homo sapiens)

Organism:: Homo sapiens

13078 Series
352485 Samples

Platform

Accession:: GPL18573

ID:: 100018573

Select item 3021788593.

RAS2 H4 ChIP-seq

Organism:: Homo sapiens

Source name:: IMR90 fibroblasts

Platform:: GPL18573
Series:: GSE81969

Sample

Accession:: GSM2178859

ID:: 302178859

SRA Run Selector

Select item 3021788584.

RAS1 H4 ChIP-seq

Organism:: Homo sapiens

Source name:: IMR90 fibroblasts

Platform:: GPL18573
Series:: GSE81969

Sample

Accession:: GSM2178858

ID:: 302178858

SRA Run Selector

Select item 3021788575.

Control2 H4 ChIP-seq

Organism:: Homo sapiens

Source name:: IMR90 fibroblasts

Platform:: GPL18573
Series:: GSE81969

Sample

Accession:: GSM2178857

ID:: 302178857

SRA Run Selector

Select item 3021788566.

Control1 H4 ChIP-seq

Organism:: Homo sapiens

Source name:: IMR90 fibroblasts

Platform:: GPL18573
Series:: GSE81969

Sample

Accession:: GSM2178856

ID:: 302178856

SRA Run Selector

Select item 3021788557.

RAS2 H4K20me3 ChIP-seq

Organism:: Homo sapiens

Source name:: IMR90 fibroblasts

Platform:: GPL18573
Series:: GSE81969

Sample

Accession:: GSM2178855

ID:: 302178855

SRA Run Selector

Select item 3021788548.

RAS1 H4K20me3 ChIP-seq

Organism:: Homo sapiens

Source name:: IMR90 fibroblasts

Platform:: GPL18573
Series:: GSE81969

Sample

Accession:: GSM2178854

ID:: 302178854

SRA Run Selector

Select item 3021788539.

Control2 H4K20me3 ChIP-seq

Organism:: Homo sapiens

Source name:: IMR90 fibroblasts

Platform:: GPL18573
Series:: GSE81969

Sample

Accession:: GSM2178853

ID:: 302178853

SRA Run Selector

Select item 30217885210.

Control1 H4K20me3 ChIP-seq

Organism:: Homo sapiens

Source name:: IMR90 fibroblasts

Platform:: GPL18573
Series:: GSE81969

Sample

Accession:: GSM2178852

ID:: 302178852

SRA Run Selector

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