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Items: 8

1.

Effects of isoxazole (ISX) on long-term cultured human islets

(Submitter supplied) Novel strategies are needed to modulate β-cell differentiation and function as potential β-cell replacement or restorative therapies for diabetes. We previously demonstrated that small molecules based on the isoxazole scaffold drive neuroendocrine phenotypes. The nature of the effects of isoxazole compounds on β cells was incompletely defined. We find that isoxazole largely induced genes that support neuroendocrine and β-cell phenotypes, and suppressed a set of genes important for proliferation. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL17585
6 Samples
Download data: CEL, CHP
Series
Accession:
GSE74240
ID:
200074240

PubMed Full text in PMC Similar studies Analyze with GEO2R

2.

[HTA-2_0] Affymetrix Human Transcriptome Array 2.0 [probe set (exon) version]

(Submitter supplied) See manufacturers website
Organism:
Homo sapiens
88 Series
3 Related Platforms
2677 Samples
Download data
Platform
Accession:
GPL17585
ID:
100017585

3.

ISX n3

Organism:
Homo sapiens
Source name:
Long-term cultured Human Pancreatic Islet cells
Platform:
GPL17585
Series:
GSE74240
Download data: CEL, CHP
Sample
Accession:
GSM1915213
ID:
301915213

4.

DMSO n3

Organism:
Homo sapiens
Source name:
Long-term cultured Human Pancreatic Islet cells
Platform:
GPL17585
Series:
GSE74240
Download data: CEL, CHP
Sample
Accession:
GSM1915212
ID:
301915212

5.

ISX n2

Organism:
Homo sapiens
Source name:
Long-term cultured Human Pancreatic Islet cells
Platform:
GPL17585
Series:
GSE74240
Download data: CEL, CHP
Sample
Accession:
GSM1915211
ID:
301915211

6.

DMSO n2

Organism:
Homo sapiens
Source name:
Long-term cultured Human Pancreatic Islet cells
Platform:
GPL17585
Series:
GSE74240
Download data: CEL, CHP
Sample
Accession:
GSM1915210
ID:
301915210

7.

ISX n1

Organism:
Homo sapiens
Source name:
Long-term cultured Human Pancreatic Islet cells
Platform:
GPL17585
Series:
GSE74240
Download data: CEL, CHP
Sample
Accession:
GSM1915209
ID:
301915209

8.

DMSO n1

Organism:
Homo sapiens
Source name:
Long-term cultured Human Pancreatic Islet cells
Platform:
GPL17585
Series:
GSE74240
Download data: CEL, CHP
Sample
Accession:
GSM1915208
ID:
301915208

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