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Items: 11

1.

Core pathway mutations induce de-differentiation of murine astrocytes into glioblastoma stem cells that are sensitive to radiation, but resistant to temozolomide (FAIRE-seq)

(Submitter supplied) Introduction: Glioma stem cells isolated from human glioblastomas are resistant to radiation and cytotoxic chemotherapy and may drive tumor recurrence. Treatment efficacy may depend on the presence of glioma stem cells, expression of DNA repair enzymes such as methylguanine methyltransferase (MGMT), or transcriptome subtype. Methods: To model genetic alterations in the core signaling pathways of human glioblastoma, we induced conditional Rb knockout, Kras activation, and Pten deletion mutations in cortical murine astrocytes. more...
Organism:
Mus musculus
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL19057
9 Samples
Download data: BW
Series
Accession:
GSE73262
ID:
200073262

PubMed Full text in PMC Similar studies SRA Run Selector

2.

Illumina NextSeq 500 (Mus musculus)

Organism:
Mus musculus
10765 Series
306119 Samples
Download data
Platform
Accession:
GPL19057
ID:
100019057

3.

TRP2-FAIRE

Organism:
Mus musculus
Source name:
astrocytes
Platform:
GPL19057
Series:
GSE73262 GSE75592
Download data: BW
Sample
Accession:
GSM1889820
ID:
301889820

SRA Run Selector

4.

TRP1-FAIRE

Organism:
Mus musculus
Source name:
astrocytes
Platform:
GPL19057
Series:
GSE73262 GSE75592
Download data: BW
Sample
Accession:
GSM1889819
ID:
301889819

SRA Run Selector

5.

TR3-FAIRE

Organism:
Mus musculus
Source name:
astrocytes
Platform:
GPL19057
Series:
GSE73262 GSE75592
Download data: BW
Sample
Accession:
GSM1889818
ID:
301889818

SRA Run Selector

6.

TR2-FAIRE

Organism:
Mus musculus
Source name:
astrocytes
Platform:
GPL19057
Series:
GSE73262 GSE75592
Download data: BW
Sample
Accession:
GSM1889817
ID:
301889817

SRA Run Selector

7.

TR1-FAIRE

Organism:
Mus musculus
Source name:
astrocytes
Platform:
GPL19057
Series:
GSE73262 GSE75592
Download data: BW
Sample
Accession:
GSM1889816
ID:
301889816

SRA Run Selector

8.

T1-FAIRE

Organism:
Mus musculus
Source name:
astrocytes
Platform:
GPL19057
Series:
GSE73262 GSE75592
Download data: BW
Sample
Accession:
GSM1889815
ID:
301889815

SRA Run Selector

9.

T2-FAIRE

Organism:
Mus musculus
Source name:
astrocytes
Platform:
GPL19057
Series:
GSE73262 GSE75592
Download data: BW
Sample
Accession:
GSM1889814
ID:
301889814

SRA Run Selector

10.

AC2-FAIRE

Organism:
Mus musculus
Source name:
astrocytes
Platform:
GPL19057
Series:
GSE73262 GSE75592
Download data: BW
Sample
Accession:
GSM1889813
ID:
301889813

SRA Run Selector

11.

AC1-FAIRE

Organism:
Mus musculus
Source name:
astrocytes
Platform:
GPL19057
Series:
GSE73262 GSE75592
Download data: BW
Sample
Accession:
GSM1889812
ID:
301889812

SRA Run Selector

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db=gds|term=GSE73262[Accession]|query=1|qty=2|blobid=MCID_680a1119e4d5e36a8607845d|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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