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Items: 8

1.

Paraoxonase 2 Serves a Proapopotic Function in Mouse and Human Cells in Response to the Pseudomonas aeruginosa Quorum-Sensing Molecule N-(3-oxododecanoyl)-Homoserine Lactone.

(Submitter supplied) Pseudomonas aeruginosa use quorum-sensing molecules, including N-(3-oxododecanoyl)-homoserine lactone (C12), for intercellular communication. C12 activated apoptosis in mouse embryo fibroblasts (MEF) from both wild type (WT) and Bax/Bak double knock-out mice (WT MEF and DKO MEF that were responsive to C12, DKOR MEF): nuclei fragmented; mitochondrial membrane potential (∆ψmito) depolarized; Ca2+ was released from the endoplasmic reticulum (ER), increasing cytosolic [Ca2+] (Cacyto); caspase 3/7 was activated. more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL17021
6 Samples
Download data: TXT
Series
Accession:
GSE65935
ID:
200065935

PubMed Full text in PMC Similar studies SRA Run Selector

2.

Illumina HiSeq 2500 (Mus musculus)

Organism:
Mus musculus
11373 Series
304227 Samples
Download data
Platform
Accession:
GPL17021
ID:
100017021

3.

DKONR_MEF2

Organism:
Mus musculus
Source name:
Mouse embryo fibroblast 
Platform:
GPL17021
Series:
GSE65935
Download data
Sample
Accession:
GSM1611445
ID:
301611445

SRA Run Selector

4.

DKONR_MEF1

Organism:
Mus musculus
Source name:
Mouse embryo fibroblast 
Platform:
GPL17021
Series:
GSE65935
Download data
Sample
Accession:
GSM1611444
ID:
301611444

SRA Run Selector

5.

DKOR_MEF2

Organism:
Mus musculus
Source name:
Mouse embryo fibroblast 
Platform:
GPL17021
Series:
GSE65935
Download data
Sample
Accession:
GSM1611443
ID:
301611443

SRA Run Selector

6.

DKOR_MEF1

Organism:
Mus musculus
Source name:
Mouse embryo fibroblast 
Platform:
GPL17021
Series:
GSE65935
Download data
Sample
Accession:
GSM1611442
ID:
301611442

SRA Run Selector

7.

WT_MEF2

Organism:
Mus musculus
Source name:
Mouse embryo fibroblast 
Platform:
GPL17021
Series:
GSE65935
Download data
Sample
Accession:
GSM1611441
ID:
301611441

SRA Run Selector

8.

WT_MEF1

Organism:
Mus musculus
Source name:
Mouse embryo fibroblast 
Platform:
GPL17021
Series:
GSE65935
Download data
Sample
Accession:
GSM1611440
ID:
301611440

SRA Run Selector

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