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Items: 1 to 20 of 57

1.

Divergent transcriptional activation by glucocorticoids in mouse and human macrophages is the result of gain and loss of enhancers

(Submitter supplied) Macrophages are amongst the major targets of glucocorticoids (GC) as therapeutic anti-inflammatory agents. Here we show that GC treatment of mouse and human macrophages initiates a cascade of induced gene expression including many anti-inflammatory genes. Inducible binding of the glucocorticoid receptor (GR) was detected at candidate enhancers in the vicinity of induced genes in both species and this was strongly associated with canonical GR binding motifs. more...
Organism:
Homo sapiens; Mus musculus
Type:
Expression profiling by array; Genome binding/occupancy profiling by high throughput sequencing
4 related Platforms
52 Samples
Download data: CEL
Series
Accession:
GSE61881
ID:
200061881
2.

[HT_MG-430_PM] Affymetrix HT MG-430 PM Array Plate

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html Protocol: see manufacturer's web site
Organism:
Mus musculus
13 DataSets
291 Series
9 Related Platforms
7057 Samples
Download data
Platform
Accession:
GPL11180
ID:
100011180
3.

[HT_HG-U133_Plus_PM] Affymetrix HT HG-U133+ PM Array Plate

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html Annotations derived from HT_HG-U133_Plus_PM.na31.annot.csv Protocol: see manufacturer's web site
Organism:
Homo sapiens
2 DataSets
155 Series
4 Related Platforms
14879 Samples
Download data
Platform
Accession:
GPL13158
ID:
100013158
4.

Illumina HiSeq 2500 (Mus musculus)

Platform
Accession:
GPL17021
ID:
100017021
5.

Illumina HiSeq 2500 (Homo sapiens)

Platform
Accession:
GPL16791
ID:
100016791
6.

BMDM-24h-dex100nM-rep3

Organism:
Mus musculus
Source name:
bone marrow derived macrophage
Platform:
GPL11180
Series:
GSE61879 GSE61881
Download data: CEL
Sample
Accession:
GSM1516151
ID:
301516151
7.

BMDM-10h-dex100nM-rep3

Organism:
Mus musculus
Source name:
bone marrow derived macrophage
Platform:
GPL11180
Series:
GSE61879 GSE61881
Download data: CEL
Sample
Accession:
GSM1516150
ID:
301516150
8.

BMDM-4h-dex100nM-rep3

Organism:
Mus musculus
Source name:
bone marrow derived macrophage
Platform:
GPL11180
Series:
GSE61879 GSE61881
Download data: CEL
Sample
Accession:
GSM1516149
ID:
301516149
9.

BMDM-2h-dex100nM-rep3

Organism:
Mus musculus
Source name:
bone marrow derived macrophage
Platform:
GPL11180
Series:
GSE61879 GSE61881
Download data: CEL
Sample
Accession:
GSM1516148
ID:
301516148
10.

BMDM-1h-dex100nM-rep3

Organism:
Mus musculus
Source name:
bone marrow derived macrophage
Platform:
GPL11180
Series:
GSE61879 GSE61881
Download data: CEL
Sample
Accession:
GSM1516147
ID:
301516147
11.

BMDM-baseline-rep3

Organism:
Mus musculus
Source name:
bone marrow derived macrophage
Platform:
GPL11180
Series:
GSE61879 GSE61881
Download data: CEL
Sample
Accession:
GSM1516146
ID:
301516146
12.

BMDM-24h-dex100nM-rep2

Organism:
Mus musculus
Source name:
bone marrow derived macrophage
Platform:
GPL11180
Series:
GSE61879 GSE61881
Download data: CEL
Sample
Accession:
GSM1516145
ID:
301516145
13.

mm_rep2_cont_Input

Organism:
Mus musculus
Source name:
mouse bone marrow derived macrophages
Platform:
GPL17021
Series:
GSE61877 GSE61881
Download data
Sample
Accession:
GSM1516131
ID:
301516131
14.

BMDM-10h-dex100nM-rep2

Organism:
Mus musculus
Source name:
bone marrow derived macrophage
Platform:
GPL11180
Series:
GSE61879 GSE61881
Download data: CEL
Sample
Accession:
GSM1516144
ID:
301516144
15.

mm_rep2_dex_Input

Organism:
Mus musculus
Source name:
mouse bone marrow derived macrophages
Platform:
GPL17021
Series:
GSE61877 GSE61881
Download data
Sample
Accession:
GSM1516130
ID:
301516130
16.

BMDM-4h-dex100nM-rep2

Organism:
Mus musculus
Source name:
bone marrow derived macrophage
Platform:
GPL11180
Series:
GSE61879 GSE61881
Download data: CEL
Sample
Accession:
GSM1516143
ID:
301516143
17.

mm_rep2_cont_IP

Organism:
Mus musculus
Source name:
mouse bone marrow derived macrophages
Platform:
GPL17021
Series:
GSE61877 GSE61881
Download data
Sample
Accession:
GSM1516129
ID:
301516129
18.

BMDM-2h-dex100nM-rep2

Organism:
Mus musculus
Source name:
bone marrow derived macrophage
Platform:
GPL11180
Series:
GSE61879 GSE61881
Download data: CEL
Sample
Accession:
GSM1516142
ID:
301516142
19.

mm_rep2_dex_IP

Organism:
Mus musculus
Source name:
mouse bone marrow derived macrophages
Platform:
GPL17021
Series:
GSE61877 GSE61881
Download data
Sample
Accession:
GSM1516128
ID:
301516128
20.

BMDM-1h-dex100nM-rep2

Organism:
Mus musculus
Source name:
bone marrow derived macrophage
Platform:
GPL11180
Series:
GSE61879 GSE61881
Download data: CEL
Sample
Accession:
GSM1516141
ID:
301516141
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Supplemental Content

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