GSE59116[Accession] - GEO DataSets - NCBI

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Select item 2000591161.

Core pathway mutations induce de-differentiation of murine astrocytes into glioblastoma stem cells that are sensitive to radiation but resistant to temozolomide.

(Submitter supplied) BACKGROUND: Glioma stem cells (GSCs) from human glioblastomas (GBMs) are resistant to radiation and chemotherapy and may drive recurrence. Treatment efficacy may depend on GSCs, expression of DNA repair enzymes such as methylguanine methyltransferase (MGMT), or transcriptome subtype. METHODS: To model genetic alterations in human GBM core signaling pathways, we induced Rb knockout, Kras activation, and Pten deletion mutations in cortical murine astrocytes. more...

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL11202
37 Samples

Download data: TXT

Series

Accession:: GSE59116

ID:: 200059116

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 1000112022.

Agilent-026655 Whole Mouse Genome Microarray 4x44K v2 (Probe Name version)

(Submitter supplied) *** The ID column includes the Agilent Probe Names. A different version of this platform with the Agilent Feature Extraction feature numbers in the ID column is assigned accession number GPL10333. Protocol: see manufacturer's web site at http://www.agilent.com/

Organism:: Mus musculus

344 Series
1 Related Platform
4228 Samples

Platform

Accession:: GPL11202

ID:: 100011202

Select item 3014288813.

Organism:: Mus musculus

Source name:: TRP allograft tumor_radiation (channel 1) Stratagene whole mouse reference RNA (channel 2)

Platform:: GPL11202
Series:: GSE59116

Download data: TXT

Sample

Accession:: GSM1428881

ID:: 301428881

Select item 3014288804.

Organism:: Mus musculus

Source name:: TRP allograft tumor_radiation (channel 1) Stratagene whole mouse reference RNA (channel 2)

Platform:: GPL11202
Series:: GSE59116

Download data: TXT

Sample

Accession:: GSM1428880

ID:: 301428880

Select item 3014288795.

Organism:: Mus musculus

Source name:: TRP allograft tumor_radiation (channel 1) Stratagene whole mouse reference RNA (channel 2)

Platform:: GPL11202
Series:: GSE59116

Download data: TXT

Sample

Accession:: GSM1428879

ID:: 301428879

Select item 3014288786.

Organism:: Mus musculus

Source name:: TRP allograft tumor_radiation (channel 1) Stratagene whole mouse reference RNA (channel 2)

Platform:: GPL11202
Series:: GSE59116

Download data: TXT

Sample

Accession:: GSM1428878

ID:: 301428878

Select item 3014288777.

Organism:: Mus musculus

Source name:: TRP allograft tumor_radiation (channel 1) Stratagene whole mouse reference RNA (channel 2)

Platform:: GPL11202
Series:: GSE59116

Download data: TXT

Sample

Accession:: GSM1428877

ID:: 301428877

Select item 3014288768.

Organism:: Mus musculus

Source name:: TRP allograft tumor_radiation (channel 1) Stratagene whole mouse reference RNA (channel 2)

Platform:: GPL11202
Series:: GSE59116

Download data: TXT

Sample

Accession:: GSM1428876

ID:: 301428876

Select item 3014288759.

Organism:: Mus musculus

Source name:: TRP allograft tumor_radiation (channel 1) Stratagene whole mouse reference RNA (channel 2)

Platform:: GPL11202
Series:: GSE59116

Download data: TXT

Sample

Accession:: GSM1428875

ID:: 301428875

Select item 30142887410.

Organism:: Mus musculus

Source name:: TRP allograft tumor_radiation (channel 1) Stratagene whole mouse reference RNA (channel 2)

Platform:: GPL11202
Series:: GSE59116

Download data: TXT

Sample

Accession:: GSM1428874

ID:: 301428874

Select item 30142887311.

Organism:: Mus musculus

Source name:: TRP allograft tumor_radiation (channel 1) Stratagene whole mouse reference RNA (channel 2)

Platform:: GPL11202
Series:: GSE59116

Download data: TXT

Sample

Accession:: GSM1428873

ID:: 301428873

Select item 30142887212.

Organism:: Mus musculus

Source name:: TRP allograft tumor_radiation (channel 1) Stratagene whole mouse reference RNA (channel 2)

Platform:: GPL11202
Series:: GSE59116

Download data: TXT

Sample

Accession:: GSM1428872

ID:: 301428872

Select item 30142887113.

Organism:: Mus musculus

Source name:: TRP allograft tumor_radiation (channel 1) Stratagene whole mouse reference RNA (channel 2)

Platform:: GPL11202
Series:: GSE59116

Download data: TXT

Sample

Accession:: GSM1428871

ID:: 301428871

Select item 30142887014.

Organism:: Mus musculus

Source name:: TRP allograft tumor_radiation (channel 1) Stratagene whole mouse reference RNA (channel 2)

Platform:: GPL11202
Series:: GSE59116

Download data: TXT

Sample

Accession:: GSM1428870

ID:: 301428870

Select item 30142886915.

Organism:: Mus musculus

Source name:: TRP allograft tumor_radiation (channel 1) Stratagene whole mouse reference RNA (channel 2)

Platform:: GPL11202
Series:: GSE59116

Download data: TXT

Sample

Accession:: GSM1428869

ID:: 301428869

Select item 30142886816.

Organism:: Mus musculus

Source name:: TRP allograft tumor_radiation (channel 1) Stratagene whole mouse reference RNA (channel 2)

Platform:: GPL11202
Series:: GSE59116

Download data: TXT

Sample

Accession:: GSM1428868

ID:: 301428868

Select item 30142886717.

Organism:: Mus musculus

Source name:: TRP allograft tumor_radiation (channel 1) Stratagene whole mouse reference RNA (channel 2)

Platform:: GPL11202
Series:: GSE59116

Download data: TXT

Sample

Accession:: GSM1428867

ID:: 301428867

Select item 30142886618.

Organism:: Mus musculus

Source name:: TRP allograft tumor_radiation (channel 1) Stratagene whole mouse reference RNA (channel 2)

Platform:: GPL11202
Series:: GSE59116

Download data: TXT

Sample

Accession:: GSM1428866

ID:: 301428866

Select item 30142886519.

Organism:: Mus musculus

Source name:: TRP allograft tumor_radiation (channel 1) Stratagene whole mouse reference RNA (channel 2)

Platform:: GPL11202
Series:: GSE59116

Download data: TXT

Sample

Accession:: GSM1428865

ID:: 301428865

Select item 30142886420.

Organism:: Mus musculus

Source name:: TRP allograft tumor_untreated (channel 1) Stratagene whole mouse reference RNA (channel 2)

Platform:: GPL11202
Series:: GSE59116

Download data: TXT

Sample

Accession:: GSM1428864

ID:: 301428864

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