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Items: 7

1.

Pathways Disrupted in Human ALS Motor Neurons Identified Through Genetic Correction of Mutant SOD1

(Submitter supplied) Although many distinct mutations in a variety of genes are known to cause Amyotrophic Lateral Sclerosis (ALS), it remains poorly understood how they selectively impact motor neuron biology and whether they converge on common pathways to cause neural degeneration. Here, we have combined reprogramming and stem cell differentiation approaches with genome engineering and RNA sequencing to define the transcriptional changes that are induced in human motor neurons by mutant SOD1. more...
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL11154
5 Samples
Download data: TXT
Series
Accession:
GSE54409
ID:
200054409

PubMed Full text in PMC Similar studies Analyze with GEO2RSRA Run Selector

2.

Illumina HiSeq 2000 (Homo sapiens)

Organism:
Homo sapiens
10380 Series
179920 Samples
Download data
Platform
Accession:
GPL11154
ID:
100011154

3.

SOD1 +/+ -3

Organism:
Homo sapiens
Source name:
motor neurons derived from iPSCs
Platform:
GPL11154
Series:
GSE54409
Download data: TXT
Sample
Accession:
GSM1314599
ID:
301314599

SRA Run Selector

4.

SOD1 +/+ -2

Organism:
Homo sapiens
Source name:
motor neurons derived from iPSCs
Platform:
GPL11154
Series:
GSE54409
Download data: TXT
Sample
Accession:
GSM1314598
ID:
301314598

SRA Run Selector

5.

SOD1 +/+ -1

Organism:
Homo sapiens
Source name:
motor neurons derived from iPSCs
Platform:
GPL11154
Series:
GSE54409
Download data: TXT
Sample
Accession:
GSM1314597
ID:
301314597

SRA Run Selector

6.

SOD1 A4V/+ -2

Organism:
Homo sapiens
Source name:
motor neurons derived from iPSCs
Platform:
GPL11154
Series:
GSE54409
Download data: TXT
Sample
Accession:
GSM1314596
ID:
301314596

SRA Run Selector

7.

SOD1 A4V/+ -1

Organism:
Homo sapiens
Source name:
motor neurons derived from iPSCs
Platform:
GPL11154
Series:
GSE54409
Download data: TXT
Sample
Accession:
GSM1314595
ID:
301314595

SRA Run Selector

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