GSE35262[Accession] - GEO DataSets - NCBI

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Select item 2000352621.

Genome-wide profiling of LXR, RXR and PPARα in mouse liver reveals extensive sharing of binding sites

(Submitter supplied) The liver X receptors (LXRs) are nuclear receptors that form permissive heterodimers with retinoid X receptor (RXR) and are important regulators of lipid metabolism in the liver. We have recently shown that RXR agonist-induced hypertriglyceridemia and hepatic steatosis in mice is dependent on LXR and correlates with an LXR-dependent hepatic induction of lipogenic genes. To further investigate the role of RXR and LXR in the regulation of hepatic gene expression, we have mapped the ligand-regulated genome-wide binding of these factors in mouse liver. more...

Organism:: Mus musculus

Type:: Genome binding/occupancy profiling by high throughput sequencing

Platform:: GPL11002
23 Samples

Download data: BED

Series

Accession:: GSE35262

ID:: 200035262

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 1000110022.

Illumina Genome Analyzer IIx (Mus musculus)

Organism:: Mus musculus

901 Series
7770 Samples

Platform

Accession:: GPL11002

ID:: 100011002

Select item 3008646733.

RXR ChIP WT Bexarotene

Organism:: Mus musculus

Source name:: C57BL/6 wild type mouse liver

Platform:: GPL11002
Series:: GSE35262

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Sample

Accession:: GSM864673

ID:: 300864673

SRA Run Selector

Select item 3008646724.

PPARalpha ChIP LXRdKO Control

Organism:: Mus musculus

Source name:: C57BL/6 LXRdKO mouse liver

Platform:: GPL11002
Series:: GSE35262

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Sample

Accession:: GSM864672

ID:: 300864672

SRA Run Selector

Select item 3008646715.

PPARalpha ChIP WT Control

Organism:: Mus musculus

Source name:: C57BL/6 wild type mouse liver

Platform:: GPL11002
Series:: GSE35262

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Sample

Accession:: GSM864671

ID:: 300864671

SRA Run Selector

Select item 3008646706.

LXR ChIP WT T0901317

Organism:: Mus musculus

Source name:: C57BL/6 wild type mouse liver

Platform:: GPL11002
Series:: GSE35262

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Sample

Accession:: GSM864670

ID:: 300864670

SRA Run Selector

Select item 3008646697.

LXR ChIP WT Control

Organism:: Mus musculus

Source name:: C57BL/6 wild type mouse liver

Platform:: GPL11002
Series:: GSE35262

Download data: BED

Sample

Accession:: GSM864669

ID:: 300864669

SRA Run Selector

Select item 3008646688.

LXR ChIP WT Bexarotene

Organism:: Mus musculus

Source name:: C57BL/6 wild type mouse liver

Platform:: GPL11002
Series:: GSE35262

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Sample

Accession:: GSM864668

ID:: 300864668

SRA Run Selector

Select item 3008646909.

RNAPolII ChIP LXRdKO T0901317 replicate 2

Organism:: Mus musculus

Source name:: C57BL/6 LXRdKO mouse liver

Platform:: GPL11002
Series:: GSE35262

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Sample

Accession:: GSM864690

ID:: 300864690

SRA Run Selector

Select item 30086468910.

RNAPolII ChIP LXRdKO T0901317 replicate 1

Organism:: Mus musculus

Source name:: C57BL/6 LXRdKO mouse liver

Platform:: GPL11002
Series:: GSE35262

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Sample

Accession:: GSM864689

ID:: 300864689

SRA Run Selector

Select item 30086468811.

RNAPolII ChIP LXRdKO Bexarotene replicate 2

Organism:: Mus musculus

Source name:: C57BL/6 LXRdKO mouse liver

Platform:: GPL11002
Series:: GSE35262

Download data: BED

Sample

Accession:: GSM864688

ID:: 300864688

SRA Run Selector

Select item 30086468712.

RNAPolII ChIP LXRdKO Bexarotene replicate 1

Organism:: Mus musculus

Source name:: C57BL/6 LXRdKO mouse liver

Platform:: GPL11002
Series:: GSE35262

Download data: BED

Sample

Accession:: GSM864687

ID:: 300864687

SRA Run Selector

Select item 30086468613.

RNAPolII ChIP LXRdKO Control replicate 2

Organism:: Mus musculus

Source name:: C57BL/6 LXRdKO mouse liver

Platform:: GPL11002
Series:: GSE35262

Download data: BED

Sample

Accession:: GSM864686

ID:: 300864686

SRA Run Selector

Select item 30086468514.

RNAPolII ChIP LXRdKO Control replicate 1

Organism:: Mus musculus

Source name:: C57BL/6 LXRdKO mouse liver

Platform:: GPL11002
Series:: GSE35262

Download data: BED

Sample

Accession:: GSM864685

ID:: 300864685

SRA Run Selector

Select item 30086468415.

RNAPolII ChIP WT T0901317 replicate 2

Organism:: Mus musculus

Source name:: C57BL/6 wild type mouse liver

Platform:: GPL11002
Series:: GSE35262

Download data: BED

Sample

Accession:: GSM864684

ID:: 300864684

SRA Run Selector

Select item 30086468316.

RNAPolII ChIP WT T0901317 replicate 1

Organism:: Mus musculus

Source name:: C57BL/6 wild type mouse liver

Platform:: GPL11002
Series:: GSE35262

Download data: BED

Sample

Accession:: GSM864683

ID:: 300864683

SRA Run Selector

Select item 30086468217.

RNAPolII ChIP WT Bexarotene replicate 2

Organism:: Mus musculus

Source name:: C57BL/6 wild type mouse liver

Platform:: GPL11002
Series:: GSE35262

Download data: BED

Sample

Accession:: GSM864682

ID:: 300864682

SRA Run Selector

Select item 30086468118.

RNAPolII ChIP WT Bexarotene replicate 1

Organism:: Mus musculus

Source name:: C57BL/6 wild type mouse liver

Platform:: GPL11002
Series:: GSE35262

Download data: BED

Sample

Accession:: GSM864681

ID:: 300864681

SRA Run Selector

Select item 30086468019.

RNAPolII ChIP WT Control replicate 2

Organism:: Mus musculus

Source name:: C57BL/6 wild type mouse liver

Platform:: GPL11002
Series:: GSE35262

Download data: BED

Sample

Accession:: GSM864680

ID:: 300864680

SRA Run Selector

Select item 30086467920.

RNAPolII ChIP WT Control replicate 1

Organism:: Mus musculus

Source name:: C57BL/6 wild type mouse liver

Platform:: GPL11002
Series:: GSE35262

Download data: BED

Sample

Accession:: GSM864679

ID:: 300864679

SRA Run Selector

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