GSE269888[Accession] - GEO DataSets - NCBI

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Items: 14

Select item 2002698881.

Oncogenic KRAS-dependent stromal interleukin-33 directs the pancreatic microenvironment to promote tumor growth [scRNA-seq]

(Submitter supplied) Here, we sought to understand the function of stromal interleukin-33 (IL-33) in PanIN and PDA. We collected pancreatic tissues from various mouse models of PanIN and PDA for single cell RNA sequencing to assess IL-33 expression across the microenviornment. We also implanted syngeneic orthotopic pancreatic tumors into mice harboring a conditional stromal IL-33 knockout and sequenced the resulting tumors.

Organism:: Mus musculus

Type:: Expression profiling by high throughput sequencing

Platforms:: GPL21103 GPL24247
11 Samples

Download data: H5

Series

Accession:: GSE269888

ID:: 200269888

Select item 1000242472.

Illumina NovaSeq 6000 (Mus musculus)

Organism:: Mus musculus

16347 Series
725753 Samples

Platform

Accession:: GPL24247

ID:: 100024247

Select item 1000211033.

Illumina HiSeq 4000 (Mus musculus)

Organism:: Mus musculus

6846 Series
150002 Samples

Platform

Accession:: GPL21103

ID:: 100021103

Select item 3083296244.

Pdgfra-CreERT2/+;Il33f/f-eGFP OT

Organism:: Mus musculus

Source name:: Orthotopic pancreas tumor

Platform:: GPL24247
Series:: GSE269888

Download data: H5

Sample

Accession:: GSM8329624

ID:: 308329624

SRA Run Selector

Select item 3083296235.

Pdgfra-CreERT2/+ OT

Organism:: Mus musculus

Source name:: Orthotopic pancreas tumor

Platform:: GPL24247
Series:: GSE269888

Download data: H5

Sample

Accession:: GSM8329623

ID:: 308329623

SRA Run Selector

Select item 3083296216.

iKrasG12D;Trp53R172H/+ 15 weeks ON + 1 week OFF 2

Organism:: Mus musculus

Source name:: PanIN pancreas

Platform:: GPL24247
Series:: GSE269888

Download data: H5

Sample

Accession:: GSM8329621

ID:: 308329621

SRA Run Selector

Select item 3083296207.

iKrasG12D;Trp53R172H/+ 15 weeks ON + 1 week OFF 1

Organism:: Mus musculus

Source name:: PanIN pancreas

Platform:: GPL24247
Series:: GSE269888

Download data: H5

Sample

Accession:: GSM8329620

ID:: 308329620

SRA Run Selector

Select item 3083296198.

iKrasG12D;Trp53R172H/+ 14 weeks ON 2

Organism:: Mus musculus

Source name:: PanIN pancreas

Platform:: GPL24247
Series:: GSE269888

Download data: H5

Sample

Accession:: GSM8329619

ID:: 308329619

SRA Run Selector

Select item 3083296189.

iKrasG12D;Trp53R172H/+ 14 weeks ON 1

Organism:: Mus musculus

Source name:: PanIN pancreas

Platform:: GPL24247
Series:: GSE269888

Download data: H5

Sample

Accession:: GSM8329618

ID:: 308329618

SRA Run Selector

Select item 30832961710.

iKrasG12D 5 weeks ON + 3 days OFF

Organism:: Mus musculus

Source name:: PanIN pancreas

Platform:: GPL24247
Series:: GSE269888

Download data: H5

Sample

Accession:: GSM8329617

ID:: 308329617

SRA Run Selector

Select item 30832961611.

iKrasG12D 5 weeks ON

Organism:: Mus musculus

Source name:: PanIN pancreas

Platform:: GPL24247
Series:: GSE269888

Download data: H5

Sample

Accession:: GSM8329616

ID:: 308329616

SRA Run Selector

Select item 30832961512.

Organism:: Mus musculus

Source name:: PanIN pancreas

Platform:: GPL24247
Series:: GSE269888

Download data: H5

Sample

Accession:: GSM8329615

ID:: 308329615

SRA Run Selector

Select item 30832961413.

Organism:: Mus musculus

Source name:: PanIN pancreas

Platform:: GPL24247
Series:: GSE269888

Download data: H5

Sample

Accession:: GSM8329614

ID:: 308329614

SRA Run Selector

Select item 30832962214.

iKrasG12D; Trp53R172H/+ OT 2 weeks ON + 3 days OFF

Organism:: Mus musculus

Source name:: Orthotopic pancreas tumor

Platform:: GPL21103
Series:: GSE269888

Download data: H5

Sample

Accession:: GSM8329622

ID:: 308329622

SRA Run Selector

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