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    Items: 8

    1.

    Rapid PTEFb-dependent transcriptional reorganization underpins the glioma adaptive response to radiotherapy [ChIP-Seq]

    (Submitter supplied) Using a combination of ChIP-, ATAC-, RNA-seq, and CUT&RUN in model systems of diffuse intrinsic pontine glioma and other pediatric high-grade gliomas, we observe a rapid genome-wide reorganization of active chromatin within hours of exposure to therapeutic ionizing radiation. This redistribution facilitates PTEFb-mediated pause-release of Pol II to drive nascent transcriptional induction of canonical DNA damage response programs. more...
    Organism:
    Homo sapiens
    Type:
    Genome binding/occupancy profiling by high throughput sequencing
    Platform:
    GPL24676
    6 Samples
    Download data: BW
    Series
    Accession:
    GSE227796
    ID:
    200227796

    PubMed Full text in PMC Similar studies

    2.

    Illumina NovaSeq 6000 (Homo sapiens)

    Organism:
    Homo sapiens
    22853 Series
    1048868 Samples
    Download data
    Platform
    Accession:
    GPL24676
    ID:
    100024676

    3.

    Histone_3_K27_acetylation, DIPG4, AZD4573, radiation, replicate 2

    Organism:
    Homo sapiens
    Source name:
    DIPG4
    Platform:
    GPL24676
    Series:
    GSE227796 GSE227797
    Download data: BW
    Sample
    Accession:
    GSM7108312
    ID:
    307108312

    SRA Run Selector

    4.

    Histone_3_K27_acetylation, DIPG4, AZD4573, radiation, replicate 1

    Organism:
    Homo sapiens
    Source name:
    DIPG4
    Platform:
    GPL24676
    Series:
    GSE227796 GSE227797
    Download data: BW
    Sample
    Accession:
    GSM7108311
    ID:
    307108311

    SRA Run Selector

    5.

    Histone_3_K27_acetylation, DIPG4, DMSO, radiation, replicate 2

    Organism:
    Homo sapiens
    Source name:
    DIPG4
    Platform:
    GPL24676
    Series:
    GSE227796 GSE227797
    Download data: BW
    Sample
    Accession:
    GSM7108310
    ID:
    307108310

    SRA Run Selector

    6.

    Histone_3_K27_acetylation, DIPG4, DMSO, radiation, replicate 1

    Organism:
    Homo sapiens
    Source name:
    DIPG4
    Platform:
    GPL24676
    Series:
    GSE227796 GSE227797
    Download data: BW
    Sample
    Accession:
    GSM7108309
    ID:
    307108309

    SRA Run Selector

    7.

    Histone_3_K27_acetylation, DIPG4, DMSO, replicate 2

    Organism:
    Homo sapiens
    Source name:
    DIPG4
    Platform:
    GPL24676
    Series:
    GSE227796 GSE227797
    Download data: BW
    Sample
    Accession:
    GSM7108308
    ID:
    307108308

    SRA Run Selector

    8.

    Histone_3_K27_acetylation, DIPG4, DMSO, replicate 1

    Organism:
    Homo sapiens
    Source name:
    DIPG4
    Platform:
    GPL24676
    Series:
    GSE227796 GSE227797
    Download data: BW
    Sample
    Accession:
    GSM7108307
    ID:
    307108307

    SRA Run Selector

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