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Items: 1 to 20 of 141

1.

Mitotic chromosomes are self-entangled and disentangle through a Topoisomerase II-dependent two stage exit from mitosis

(Submitter supplied) The topological state of chromosomes determines their mechanical properties, dynamics, and function. Recent work indicated that interphase chromosomes are largely free of entanglements. Here, we use Hi-C, polymer simulations and multi-contact 3C, and propose that, in contrast, mitotic chromosomes are self-entangled. We explore how a mitotic self-entangled state is converted into an unentangled interphase state during mitotic exit. more...
Organism:
Homo sapiens
Type:
Other
Platforms:
GPL28352 GPL30173 GPL20301
137 Samples
Download data: MCOOL, TXT
Series
Accession:
GSE198610
ID:
200198610

PubMed Similar studies

2.

NextSeq 2000 (Homo sapiens)

Organism:
Homo sapiens
1632 Series
35288 Samples
Download data
Platform
Accession:
GPL30173
ID:
100030173

3.

Sequel II (Homo sapiens)

Organism:
Homo sapiens
152 Series
651 Samples
Download data
Platform
Accession:
GPL28352
ID:
100028352

4.

Illumina HiSeq 4000 (Homo sapiens)

Organism:
Homo sapiens
8976 Series
205008 Samples
Download data
Platform
Accession:
GPL20301
ID:
100020301

5.

DpnII Hi-C on HeLa S3 MR DMSO or Merb added at t2: t4 Merb R2

Organism:
Homo sapiens
Source name:
uterine/cervical adenocarcinoma cell line
Platform:
GPL20301
Series:
GSE198610
Download data: MCOOL
Sample
Accession:
GSM7844000
ID:
307844000

SRA Run Selector

6.

DpnII Hi-C on HeLa S3 MR DMSO or Merb added at t2: t4 DMSO R2

Organism:
Homo sapiens
Source name:
uterine/cervical adenocarcinoma cell line
Platform:
GPL20301
Series:
GSE198610
Download data: MCOOL
Sample
Accession:
GSM7843999
ID:
307843999

SRA Run Selector

7.

DpnII Hi-C on HeLa S3 MR DMSO or Merb added at t2: t0 Mitotic R2

Organism:
Homo sapiens
Source name:
uterine/cervical adenocarcinoma cell line
Platform:
GPL20301
Series:
GSE198610
Download data: MCOOL
Sample
Accession:
GSM7843998
ID:
307843998

SRA Run Selector

8.

DpnII Hi-C on HCT116 + Rad21-mAC async 2hr: IAA + ICRF-193 R3

Organism:
Homo sapiens
Source name:
colorectal carcinoma cell line
Platform:
GPL20301
Series:
GSE198610
Download data: MCOOL
Sample
Accession:
GSM5953624
ID:
305953624

SRA Run Selector

9.

DpnII Hi-C on HCT116 + Rad21-mAC async 2hr: ICRF-193 R3

Organism:
Homo sapiens
Source name:
colorectal carcinoma cell line
Platform:
GPL20301
Series:
GSE198610
Download data: MCOOL
Sample
Accession:
GSM5953623
ID:
305953623

SRA Run Selector

10.

DpnII Hi-C on HCT116 + Rad21-mAC async 2hr: IAA R3

Organism:
Homo sapiens
Source name:
colorectal carcinoma cell line
Platform:
GPL20301
Series:
GSE198610
Download data: MCOOL
Sample
Accession:
GSM5953622
ID:
305953622

SRA Run Selector

11.

DpnII Hi-C on HCT116 + Rad21-mAC async 2hr: Control R3

Organism:
Homo sapiens
Source name:
colorectal carcinoma cell line
Platform:
GPL20301
Series:
GSE198610
Download data: MCOOL
Sample
Accession:
GSM5953621
ID:
305953621

SRA Run Selector

12.

DpnII Hi-C on HCT116 + Rad21-mAC async 2hr: IAA + ICRF-193 R2

Organism:
Homo sapiens
Source name:
colorectal carcinoma cell line
Platform:
GPL20301
Series:
GSE198610
Download data: MCOOL
Sample
Accession:
GSM5953620
ID:
305953620

SRA Run Selector

13.

DpnII Hi-C on HCT116 + Rad21-mAC async 2hr: ICRF-193 R2

Organism:
Homo sapiens
Source name:
colorectal carcinoma cell line
Platform:
GPL20301
Series:
GSE198610
Download data: MCOOL
Sample
Accession:
GSM5953619
ID:
305953619

SRA Run Selector

14.

DpnII Hi-C on HCT116 + Rad21-mAC async 2hr: IAA R2

Organism:
Homo sapiens
Source name:
colorectal carcinoma cell line
Platform:
GPL20301
Series:
GSE198610
Download data: MCOOL
Sample
Accession:
GSM5953618
ID:
305953618

SRA Run Selector

15.

DpnII Hi-C on HCT116 + Rad21-mAC async 2hr: Control R2

Organism:
Homo sapiens
Source name:
colorectal carcinoma cell line
Platform:
GPL20301
Series:
GSE198610
Download data: MCOOL
Sample
Accession:
GSM5953617
ID:
305953617

SRA Run Selector

16.

DpnII Hi-C on HCT116 + Rad21-mAC async 1hr: IAA + ICRF-193 R2

Organism:
Homo sapiens
Source name:
colorectal carcinoma cell line
Platform:
GPL20301
Series:
GSE198610
Download data: MCOOL
Sample
Accession:
GSM5953616
ID:
305953616

SRA Run Selector

17.

DpnII Hi-C on HCT116 + Rad21-mAC async 1hr: ICRF-193 R2

Organism:
Homo sapiens
Source name:
colorectal carcinoma cell line
Platform:
GPL20301
Series:
GSE198610
Download data: MCOOL
Sample
Accession:
GSM5953615
ID:
305953615

SRA Run Selector

18.

DpnII Hi-C on HCT116 + Rad21-mAC async 1hr: IAA R2

Organism:
Homo sapiens
Source name:
colorectal carcinoma cell line
Platform:
GPL20301
Series:
GSE198610
Download data: MCOOL
Sample
Accession:
GSM5953614
ID:
305953614

SRA Run Selector

19.

DpnII Hi-C on HCT116 + Rad21-mAC async 1hr: Control R2

Organism:
Homo sapiens
Source name:
colorectal carcinoma cell line
Platform:
GPL20301
Series:
GSE198610
Download data: MCOOL
Sample
Accession:
GSM5953613
ID:
305953613

SRA Run Selector

20.

DpnII Hi-C on HCT116 + Rad21-mAC async 1hr: Control R1

Organism:
Homo sapiens
Source name:
colorectal carcinoma cell line
Platform:
GPL20301
Series:
GSE198610
Download data: MCOOL
Sample
Accession:
GSM5953612
ID:
305953612

SRA Run Selector

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