GSE185577[Accession] - GEO DataSets - NCBI

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Select item 2001855771.

Arthritogenic SKG T cells have a transcriptional program of activation and a repertoire pruned by superantigen

(Submitter supplied) Purpose: The goals of this study were to study the transcriptome and TCR repertoire of naive CD4 T cells before the induction of arthritis in the SKG and wild-type (WT) mouse with eGFP-Nur77 as a reporter of antigen stimulation (SKGNur and WTNur). Methods: Bulk RNA sequencing was used to generate the mRNA profiles for the top 10% and bottom 10% of GFP expressing cells from three SKGNur and three WTNur BALB/c mice resulting in 12 samples overall (3 WT Low, 3 WT High, 3 SKG Low, 3 SKG High) using the Truseq Stranded mRNA kit followed by sequencing on a HiSeq 2500 sequencer. more...

Organism:: Mus musculus

Type:: Expression profiling by high throughput sequencing; Other

Platforms:: GPL24247 GPL17021
28 Samples

Download data: CSV, H5AD

Series

Accession:: GSE185577

ID:: 200185577

SRA Run Selector

Select item 1000242472.

Illumina NovaSeq 6000 (Mus musculus)

Organism:: Mus musculus

18118 Series
749568 Samples

Platform

Accession:: GPL24247

ID:: 100024247

Select item 1000170213.

Illumina HiSeq 2500 (Mus musculus)

Organism:: Mus musculus

11529 Series
306997 Samples

Platform

Accession:: GPL17021

ID:: 100017021

Select item 3056188424.

tcr_Sample 4b [WT Low TCR Rep 2]

Organism:: Mus musculus

Source name:: naive CD4 T cells

Platform:: GPL24247
Series:: GSE185577

Download data: CSV

Sample

Accession:: GSM5618842

ID:: 305618842

SRA Run Selector

Select item 3056188415.

tcr_Sample 4a [WT High TCR Rep 2]

Organism:: Mus musculus

Source name:: naive CD4 T cells

Platform:: GPL24247
Series:: GSE185577

Download data: CSV

Sample

Accession:: GSM5618841

ID:: 305618841

SRA Run Selector

Select item 3056188406.

tcr_Sample 3b [SKG Low TCR Rep 2]

Organism:: Mus musculus

Source name:: naive CD4 T cells

Platform:: GPL24247
Series:: GSE185577

Download data: CSV

Sample

Accession:: GSM5618840

ID:: 305618840

SRA Run Selector

Select item 3056188397.

tcr_Sample 3a [SKG High TCR Rep 2]

Organism:: Mus musculus

Source name:: naive CD4 T cells

Platform:: GPL24247
Series:: GSE185577

Download data: CSV

Sample

Accession:: GSM5618839

ID:: 305618839

SRA Run Selector

Select item 3056188388.

tcr_Sample 2b [WT Low TCR Rep 1]

Organism:: Mus musculus

Source name:: naive CD4 T cells

Platform:: GPL24247
Series:: GSE185577

Download data: CSV

Sample

Accession:: GSM5618838

ID:: 305618838

SRA Run Selector

Select item 3056188379.

tcr_Sample 2a [WT High TCR Rep 1]

Organism:: Mus musculus

Source name:: naive CD4 T cells

Platform:: GPL24247
Series:: GSE185577

Download data: CSV

Sample

Accession:: GSM5618837

ID:: 305618837

SRA Run Selector

Select item 30561883610.

tcr_Sample 1b [SKG Low TCR Rep 1]

Organism:: Mus musculus

Source name:: naive CD4 T cells

Platform:: GPL24247
Series:: GSE185577

Download data: CSV

Sample

Accession:: GSM5618836

ID:: 305618836

SRA Run Selector

Select item 30561883511.

tcr_Sample 1a [SKG High TCR Rep 1]

Organism:: Mus musculus

Source name:: naive CD4 T cells

Platform:: GPL24247
Series:: GSE185577

Download data: CSV

Sample

Accession:: GSM5618835

ID:: 305618835

SRA Run Selector

Select item 30561883412.

sc_Sample 4b [WT Low single cell Rep 2]

Organism:: Mus musculus

Source name:: naive CD4 T cells

Platform:: GPL24247
Series:: GSE185577

Sample

Accession:: GSM5618834

ID:: 305618834

SRA Run Selector

Select item 30561883313.

sc_Sample 4a [WT High single cell Rep 2]

Organism:: Mus musculus

Source name:: naive CD4 T cells

Platform:: GPL24247
Series:: GSE185577

Sample

Accession:: GSM5618833

ID:: 305618833

SRA Run Selector

Select item 30561883214.

sc_Sample 3b [SKG Low single cell Rep 2]

Organism:: Mus musculus

Source name:: naive CD4 T cells

Platform:: GPL24247
Series:: GSE185577

Sample

Accession:: GSM5618832

ID:: 305618832

SRA Run Selector

Select item 30561883115.

sc_Sample 3a [SKG High single cell Rep 2]

Organism:: Mus musculus

Source name:: naive CD4 T cells

Platform:: GPL24247
Series:: GSE185577

Sample

Accession:: GSM5618831

ID:: 305618831

SRA Run Selector

Select item 30561883016.

sc_Sample 2b [WT Low single cell Rep 1]

Organism:: Mus musculus

Source name:: naive CD4 T cells

Platform:: GPL24247
Series:: GSE185577

Sample

Accession:: GSM5618830

ID:: 305618830

SRA Run Selector

Select item 30561882917.

sc_Sample 2a [WT High single cell Rep 1]

Organism:: Mus musculus

Source name:: naive CD4 T cells

Platform:: GPL24247
Series:: GSE185577

Sample

Accession:: GSM5618829

ID:: 305618829

SRA Run Selector

Select item 30561882818.

sc_Sample 1b [SKG Low single cell Rep 1]

Organism:: Mus musculus

Source name:: naive CD4 T cells

Platform:: GPL24247
Series:: GSE185577

Sample

Accession:: GSM5618828

ID:: 305618828

SRA Run Selector

Select item 30561882719.

sc_Sample 1a [SKG High single cell Rep 1]

Organism:: Mus musculus

Source name:: naive CD4 T cells

Platform:: GPL24247
Series:: GSE185577

Sample

Accession:: GSM5618827

ID:: 305618827

SRA Run Selector

Select item 30561882620.

Sample 6b [WT High Rep 3]

Organism:: Mus musculus

Source name:: naive CD4 T cells

Platform:: GPL17021
Series:: GSE185577

Sample

Accession:: GSM5618826

ID:: 305618826

SRA Run Selector

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