GSE163249[Accession] - GEO DataSets - NCBI

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Items: 10

Select item 2001632491.

Targeted inhibition of LIFR enhances therapeutic efficacy of HDAC inhibitors in triple negative breast cancer

(Submitter supplied) Here, we examined the therapeutic utility of EC359 in improving the therapeutic efficacy of HDACi in TNBC models. BT-549 cells were treated with vehicle (DMSO), EC359, HDACi(Vorinostat), EC359+HDACi and the RNA was isolated and utilized for RNA-seq analysis. Our results demonstrated that the beneficial effect of the EC359+HDACi involves regulation of multiple genes that involved in several pathways including apoptosis, metabolism and cell cycle.

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing

Platform:: GPL21290
8 Samples

Download data: TXT

Series

Accession:: GSE163249

ID:: 200163249

PubMed Full text in PMC Similar studies Analyze with GEO2R SRA Run Selector

Select item 1000212902.

Illumina HiSeq 3000 (Homo sapiens)

Organism:: Homo sapiens

1170 Series
28996 Samples

Platform

Accession:: GPL21290

ID:: 100021290

Select item 3049756133.

BT_549_SAHA(Vorinostat)_2

Organism:: Homo sapiens

Source name:: BT-549, triple negative breast cancer cell line

Platform:: GPL21290
Series:: GSE163249

Download data: TXT

Sample

Accession:: GSM4975613

ID:: 304975613

SRA Run Selector

Select item 3049756114.

BT_549_SAHA(Vorinostat)_1

Organism:: Homo sapiens

Source name:: BT-549, triple negative breast cancer cell line

Platform:: GPL21290
Series:: GSE163249

Download data: TXT

Sample

Accession:: GSM4975611

ID:: 304975611

SRA Run Selector

Select item 3049756085.

Organism:: Homo sapiens

Source name:: BT-549, triple negative breast cancer cell line

Platform:: GPL21290
Series:: GSE163249

Download data: TXT

Sample

Accession:: GSM4975608

ID:: 304975608

SRA Run Selector

Select item 3049756066.

Organism:: Homo sapiens

Source name:: BT-549, triple negative breast cancer cell line

Platform:: GPL21290
Series:: GSE163249

Download data: TXT

Sample

Accession:: GSM4975606

ID:: 304975606

SRA Run Selector

Select item 3049756037.

BT_549_EC359+SAHA_2

Organism:: Homo sapiens

Source name:: BT-549, triple negative breast cancer cell line

Platform:: GPL21290
Series:: GSE163249

Download data: TXT

Sample

Accession:: GSM4975603

ID:: 304975603

SRA Run Selector

Select item 3049756018.

BT_549_EC359+SAHA_1

Organism:: Homo sapiens

Source name:: BT-549, triple negative breast cancer cell line

Platform:: GPL21290
Series:: GSE163249

Download data: TXT

Sample

Accession:: GSM4975601

ID:: 304975601

SRA Run Selector

Select item 3049755999.

BT_549_Vehicle_2

Organism:: Homo sapiens

Source name:: BT-549, triple negative breast cancer cell line

Platform:: GPL21290
Series:: GSE163249

Download data: TXT

Sample

Accession:: GSM4975599

ID:: 304975599

SRA Run Selector

Select item 30497559710.

BT_549_Vehicle_1

Organism:: Homo sapiens

Source name:: BT-549, triple negative breast cancer cell line

Platform:: GPL21290
Series:: GSE163249

Download data: TXT

Sample

Accession:: GSM4975597

ID:: 304975597

SRA Run Selector

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