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Pachytene piRNA Genes Are Rapidly Diverging Among Modern Humans

In the fetal mouse testis, PIWI Interacting RNAs (piRNAs) guide PIWI proteins to silence transposons, but after birth, most post-pubertal pachytene piRNAs map to genome uniquely and are thought to regulate genes required for male fertility. In human...

Species: Macaca mulatta; Homo sapiens; Mus musculusType: Expression profiling by high throughput sequencing; Non-coding RNA profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing

Dataset: GSE135791

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Items: 1 to 20 of 76

1.

Pachytene piRNA Genes Are Rapidly Diverging Among Modern Humans

(Submitter supplied) In the fetal mouse testis, PIWI Interacting RNAs (piRNAs) guide PIWI proteins to silence transposons, but after birth, most post-pubertal pachytene piRNAs map to genome uniquely and are thought to regulate genes required for male fertility. In human males, the developmental classes, precise genomic origins, and transcriptional regulation of post-natal piRNAs remain undefined. Here, we demarcate the genes and transcripts that produce post-natal piRNAs in human juvenile and adult testes. more...
Organism:
Macaca mulatta; Homo sapiens; Mus musculus
Type:
Expression profiling by high throughput sequencing; Non-coding RNA profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing
Platforms:
GPL21120 GPL18573 GPL19057
72 Samples
Download data: BW, NARROWPEAK, TXT
Series
Accession:
GSE135791
ID:
200135791
2.

Illumina NextSeq 500 (Macaca mulatta)

Organism:
Macaca mulatta
37 Series
1141 Samples
Download data
Platform
Accession:
GPL21120
ID:
100021120
3.

Illumina NextSeq 500 (Mus musculus)

Platform
Accession:
GPL19057
ID:
100019057
4.

Illumina NextSeq 500 (Homo sapiens)

Platform
Accession:
GPL18573
ID:
100018573
5.

Mouse0MIWI-KO-rep2

Organism:
Mus musculus
Source name:
Testis
Platform:
GPL19057
Series:
GSE135791
Download data: TXT
Sample
Accession:
GSM4030267
ID:
304030267
6.

Mouse0MIWI-KO-rep1

Organism:
Mus musculus
Source name:
Testis
Platform:
GPL19057
Series:
GSE135791
Download data: TXT
Sample
Accession:
GSM4030266
ID:
304030266
7.

Mouse-MIWI-HET-rep2

Organism:
Mus musculus
Source name:
Testis
Platform:
GPL19057
Series:
GSE135791
Download data: TXT
Sample
Accession:
GSM4030265
ID:
304030265
8.

Mouse-MIWI-HET-rep1

Organism:
Mus musculus
Source name:
Testis
Platform:
GPL19057
Series:
GSE135791
Download data: TXT
Sample
Accession:
GSM4030264
ID:
304030264
9.

Mouse-AMYB-minus-minus-smallRNAseq-rep2

Organism:
Mus musculus
Source name:
Testis
Platform:
GPL19057
Series:
GSE135791
Download data: TXT
Sample
Accession:
GSM4030263
ID:
304030263
10.

Mouse-AMYB-minus-minus-smallRNAseq-rep1

Organism:
Mus musculus
Source name:
Testis
Platform:
GPL19057
Series:
GSE135791
Download data: TXT
Sample
Accession:
GSM4030262
ID:
304030262
11.

Human-ChIPseq-H3K4me3_ChIP-S1

Organism:
Homo sapiens
Source name:
Kidney
Platform:
GPL18573
Series:
GSE135791
Download data: BW, NARROWPEAK
Sample
Accession:
GSM4030259
ID:
304030259
12.

Human-ChIPseq-H3K4me3_input-A17

Organism:
Homo sapiens
Source name:
Testis
Platform:
GPL18573
Series:
GSE135791
Download data: BW
Sample
Accession:
GSM4030258
ID:
304030258
13.

Human-ChIPseq-H3K4me3_ChIP-A17

Organism:
Homo sapiens
Source name:
Testis
Platform:
GPL18573
Series:
GSE135791
Download data: BW, NARROWPEAK
Sample
Accession:
GSM4030257
ID:
304030257
14.

Human-ChIPseq-H3K4me3_input-A15

Organism:
Homo sapiens
Source name:
Testis
Platform:
GPL18573
Series:
GSE135791
Download data: BW
Sample
Accession:
GSM4030256
ID:
304030256
15.

Human-ChIPseq-H3K4me3_ChIP-A15

Organism:
Homo sapiens
Source name:
Testis
Platform:
GPL18573
Series:
GSE135791
Download data: BW, NARROWPEAK
Sample
Accession:
GSM4030255
ID:
304030255
16.

Human-ChIPseq-H3K4me3_input-A1

Organism:
Homo sapiens
Source name:
Testis
Platform:
GPL18573
Series:
GSE135791
Download data: BW
Sample
Accession:
GSM4030254
ID:
304030254
17.

Human-ChIPseq-H3K4me3_ChIP-A1

Organism:
Homo sapiens
Source name:
Testis
Platform:
GPL18573
Series:
GSE135791
Download data: BW, NARROWPEAK
Sample
Accession:
GSM4030253
ID:
304030253
18.

Human-ChIPseq-input-S1

Organism:
Homo sapiens
Source name:
Kidney
Platform:
GPL18573
Series:
GSE135791
Download data: BW
Sample
Accession:
GSM4030252
ID:
304030252
19.

Human-ChIPseq-AMYB_ChIP-S1

Organism:
Homo sapiens
Source name:
Kidney
Platform:
GPL18573
Series:
GSE135791
Download data: BW, NARROWPEAK
Sample
Accession:
GSM4030251
ID:
304030251
20.

Human-ChIPseq-AMYB_input-A17

Organism:
Homo sapiens
Source name:
Testis
Platform:
GPL18573
Series:
GSE135791
Download data: BW
Sample
Accession:
GSM4030250
ID:
304030250
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Supplemental Content

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