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Items: 1 to 20 of 1477

1.

Germline-Encoded Affinity for Cognate Antigen Enables Vaccine Amplification of a Human Broadly Neutralizing Response Against Influenza Virus

(Submitter supplied) Antibodies display antigen-binding loops comprised of a hypervariable CDRH3 and V gene-encoded CDRs, where the latter may harbor gene-endowed or ‘public’ targeting solutions. To test this, we generated transgenic mice containing human CDRH3 diversity but simultaneously constrained to individual human immunoglobulin VH genes, including IGHV1-69, which shows biased usage in human broadly neutralizing antibodies (bnAbs) targeting the hemagglutinin stalk of Group 1 influenza A viruses. more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL16417
1475 Samples
Download data: TXT
Series
Accession:
GSE135761
ID:
200135761

SRA Run Selector

2.

Illumina MiSeq (Mus musculus)

Organism:
Mus musculus
972 Series
22872 Samples
Download data
Platform
Accession:
GPL16417
ID:
100016417

3.

BCR13_Bulk_IGHV1-2

Organism:
Mus musculus
Source name:
IGHV1-2_VH_Naïve Bulk_Splenic B cells
Platform:
GPL16417
Series:
GSE135761
Download data: TXT
Sample
Accession:
GSM4029204
ID:
304029204

SRA Run Selector

4.

BCR7_Bulk_IGHV1-69

Organism:
Mus musculus
Source name:
IGHV1-69_VH_Naïve Bulk_Splenic B cells
Platform:
GPL16417
Series:
GSE135761
Download data: TXT
Sample
Accession:
GSM4029203
ID:
304029203

SRA Run Selector

5.

BCR35__S0240_S240

Organism:
Mus musculus
Source name:
IGHV1-69_VH_Adoptive Transfer_Splenic B cells
Platform:
GPL16417
Series:
GSE135761
Download data
Sample
Accession:
GSM4029202
ID:
304029202

SRA Run Selector

6.

BCR35__S0236_S236

Organism:
Mus musculus
Source name:
IGHV1-69_VH_Adoptive Transfer_Splenic B cells
Platform:
GPL16417
Series:
GSE135761
Download data
Sample
Accession:
GSM4029201
ID:
304029201

SRA Run Selector

7.

BCR35__S0235_S235

Organism:
Mus musculus
Source name:
IGHV1-69_VH_Adoptive Transfer_Splenic B cells
Platform:
GPL16417
Series:
GSE135761
Download data
Sample
Accession:
GSM4029200
ID:
304029200

SRA Run Selector

8.

BCR35__S0233_S233

Organism:
Mus musculus
Source name:
IGHV1-69_VH_Adoptive Transfer_Splenic B cells
Platform:
GPL16417
Series:
GSE135761
Download data
Sample
Accession:
GSM4029199
ID:
304029199

SRA Run Selector

9.

BCR35__S0231_S231

Organism:
Mus musculus
Source name:
IGHV1-69_VH_Adoptive Transfer_Splenic B cells
Platform:
GPL16417
Series:
GSE135761
Download data
Sample
Accession:
GSM4029198
ID:
304029198

SRA Run Selector

10.

BCR35__S0230_S230

Organism:
Mus musculus
Source name:
IGHV1-69_VH_Adoptive Transfer_Splenic B cells
Platform:
GPL16417
Series:
GSE135761
Download data
Sample
Accession:
GSM4029197
ID:
304029197

SRA Run Selector

11.

BCR35__S0228_S228

Organism:
Mus musculus
Source name:
IGHV1-69_VH_Adoptive Transfer_Splenic B cells
Platform:
GPL16417
Series:
GSE135761
Download data
Sample
Accession:
GSM4029196
ID:
304029196

SRA Run Selector

12.

BCR35__S0226_S226

Organism:
Mus musculus
Source name:
IGHV1-69_VH_Adoptive Transfer_Splenic B cells
Platform:
GPL16417
Series:
GSE135761
Download data
Sample
Accession:
GSM4029195
ID:
304029195

SRA Run Selector

13.

BCR35__S0225_S225

Organism:
Mus musculus
Source name:
IGHV1-69_VH_Adoptive Transfer_Splenic B cells
Platform:
GPL16417
Series:
GSE135761
Download data
Sample
Accession:
GSM4029194
ID:
304029194

SRA Run Selector

14.

BCR35__S0224_S224

Organism:
Mus musculus
Source name:
IGHV1-69_VH_Adoptive Transfer_Splenic B cells
Platform:
GPL16417
Series:
GSE135761
Download data
Sample
Accession:
GSM4029193
ID:
304029193

SRA Run Selector

15.

BCR35__S0223_S223

Organism:
Mus musculus
Source name:
IGHV1-69_VH_Adoptive Transfer_Splenic B cells
Platform:
GPL16417
Series:
GSE135761
Download data
Sample
Accession:
GSM4029192
ID:
304029192

SRA Run Selector

16.

BCR35__S0222_S222

Organism:
Mus musculus
Source name:
IGHV1-69_VH_Adoptive Transfer_Splenic B cells
Platform:
GPL16417
Series:
GSE135761
Download data
Sample
Accession:
GSM4029191
ID:
304029191

SRA Run Selector

17.

BCR35__S0221_S221

Organism:
Mus musculus
Source name:
IGHV1-69_VH_Adoptive Transfer_Splenic B cells
Platform:
GPL16417
Series:
GSE135761
Download data
Sample
Accession:
GSM4029190
ID:
304029190

SRA Run Selector

18.

BCR35__S0220_S220

Organism:
Mus musculus
Source name:
IGHV1-69_VH_Adoptive Transfer_Splenic B cells
Platform:
GPL16417
Series:
GSE135761
Download data
Sample
Accession:
GSM4029189
ID:
304029189

SRA Run Selector

19.

BCR35__S0219_S219

Organism:
Mus musculus
Source name:
IGHV1-69_VH_Adoptive Transfer_Splenic B cells
Platform:
GPL16417
Series:
GSE135761
Download data
Sample
Accession:
GSM4029188
ID:
304029188

SRA Run Selector

20.

BCR35__S0216_S216

Organism:
Mus musculus
Source name:
IGHV1-69_VH_Adoptive Transfer_Splenic B cells
Platform:
GPL16417
Series:
GSE135761
Download data
Sample
Accession:
GSM4029187
ID:
304029187

SRA Run Selector

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