GSE112463[Accession] - GEO DataSets - NCBI

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Items: 15

Select item 2001124631.

Identification of Novel Regulatory Genes in APAP Induced Hepatocyte Toxicity by a Genome-Wide CRISPR-Cas9 Screen

(Submitter supplied) Acetaminophen (APAP) is a commonly used analgesic responsible for more than half of acute liver failure cases. Identification of previously unknown genetic risk factors would provide mechanistic insights and novel therapeutic targets for APAP-induced liver injury. This study used a genome-wide CRISPR-Cas9 screen to evaluate genes that are protective against, or cause susceptibility to, APAP-induced liver injury. more...

Organism:: Escherichia coli; Homo sapiens

Type:: Expression profiling by high throughput sequencing

Platforms:: GPL20045 GPL18460
12 Samples

Download data: TXT

Series

Accession:: GSE112463

ID:: 200112463

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 1000200452.

Illumina HiSeq 1500 (Escherichia coli)

Organism:: Escherichia coli

3 Series
87 Samples

Platform

Accession:: GPL20045

ID:: 100020045

Select item 1000184603.

Illumina HiSeq 1500 (Homo sapiens)

Organism:: Homo sapiens

421 Series
7322 Samples

Platform

Accession:: GPL18460

ID:: 100018460

Select item 3030705024.

Organism:: Escherichia coli

Source name:: GeCKOv2 plasmid library

Platform:: GPL20045
Series:: GSE112463

Sample

Accession:: GSM3070502

ID:: 303070502

SRA Run Selector

Select item 3030705015.

Organism:: Escherichia coli

Source name:: GeCKOv2 plasmid library

Platform:: GPL20045
Series:: GSE112463

Sample

Accession:: GSM3070501

ID:: 303070501

SRA Run Selector

Select item 3030705126.

Organism:: Homo sapiens

Source name:: HuH7 human hepatocarcinoma cell line

Platform:: GPL18460
Series:: GSE112463

Sample

Accession:: GSM3070512

ID:: 303070512

SRA Run Selector

Select item 3030705117.

Organism:: Homo sapiens

Source name:: HuH7 human hepatocarcinoma cell line

Platform:: GPL18460
Series:: GSE112463

Sample

Accession:: GSM3070511

ID:: 303070511

SRA Run Selector

Select item 3030705108.

Organism:: Homo sapiens

Source name:: HuH7 human hepatocarcinoma cell line

Platform:: GPL18460
Series:: GSE112463

Sample

Accession:: GSM3070510

ID:: 303070510

SRA Run Selector

Select item 3030705099.

Organism:: Homo sapiens

Source name:: HuH7 human hepatocarcinoma cell line

Platform:: GPL18460
Series:: GSE112463

Sample

Accession:: GSM3070509

ID:: 303070509

SRA Run Selector

Select item 30307050810.

Organism:: Homo sapiens

Source name:: HuH7 human hepatocarcinoma cell line

Platform:: GPL18460
Series:: GSE112463

Sample

Accession:: GSM3070508

ID:: 303070508

SRA Run Selector

Select item 30307050711.

Organism:: Homo sapiens

Source name:: HuH7 human hepatocarcinoma cell line

Platform:: GPL18460
Series:: GSE112463

Sample

Accession:: GSM3070507

ID:: 303070507

SRA Run Selector

Select item 30307050612.

Organism:: Homo sapiens

Source name:: HuH7 human hepatocarcinoma cell line

Platform:: GPL18460
Series:: GSE112463

Sample

Accession:: GSM3070506

ID:: 303070506

SRA Run Selector

Select item 30307050513.

Organism:: Homo sapiens

Source name:: HuH7 human hepatocarcinoma cell line

Platform:: GPL18460
Series:: GSE112463

Sample

Accession:: GSM3070505

ID:: 303070505

SRA Run Selector

Select item 30307050414.

Organism:: Homo sapiens

Source name:: HuH7 human hepatocarcinoma cell line

Platform:: GPL18460
Series:: GSE112463

Sample

Accession:: GSM3070504

ID:: 303070504

SRA Run Selector

Select item 30307050315.

Organism:: Homo sapiens

Source name:: HuH7 human hepatocarcinoma cell line

Platform:: GPL18460
Series:: GSE112463

Sample

Accession:: GSM3070503

ID:: 303070503

SRA Run Selector

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