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Items: 11

1.

Boosting ATM activity alleviates ageing and extends lifespan in a mouse model of progeria.

(Submitter supplied) Protein deacetylase SIRT6 and protein kinase ATM both decline during aging, which are of importance in regualtion of glucose metabolism . To explore the mechnisms of SIRT6 and ATM in glycolysis, we analysed the gene expressions in murine embryonic fibroblast cells generated from wildtype, Sirt6-/-, or Atm-/- mice.
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL21273
9 Samples
Download data: TXT
Series
Accession:
GSE109280
ID:
200109280
2.

HiSeq X Ten (Mus musculus)

Platform
Accession:
GPL21273
ID:
100021273
3.

Atm-/- -3

Organism:
Mus musculus
Source name:
murine embryonic fibroblast cell
Platform:
GPL21273
Series:
GSE109280
Download data: TXT
Sample
Accession:
GSM2936424
ID:
302936424
4.

Atm-/- -2

Organism:
Mus musculus
Source name:
murine embryonic fibroblast cell
Platform:
GPL21273
Series:
GSE109280
Download data: TXT
Sample
Accession:
GSM2936423
ID:
302936423
5.

Atm-/- -1

Organism:
Mus musculus
Source name:
murine embryonic fibroblast cell
Platform:
GPL21273
Series:
GSE109280
Download data: TXT
Sample
Accession:
GSM2936422
ID:
302936422
6.

Sirt6-/- -3

Organism:
Mus musculus
Source name:
murine embryonic fibroblast cell
Platform:
GPL21273
Series:
GSE109280
Download data: TXT
Sample
Accession:
GSM2936421
ID:
302936421
7.

Sirt6-/- -2

Organism:
Mus musculus
Source name:
murine embryonic fibroblast cell
Platform:
GPL21273
Series:
GSE109280
Download data: TXT
Sample
Accession:
GSM2936420
ID:
302936420
8.

Sirt6-/- -1

Organism:
Mus musculus
Source name:
murine embryonic fibroblast cell
Platform:
GPL21273
Series:
GSE109280
Download data: TXT
Sample
Accession:
GSM2936419
ID:
302936419
9.

WT -3

Organism:
Mus musculus
Source name:
murine embryonic fibroblast cell
Platform:
GPL21273
Series:
GSE109280
Download data: TXT
Sample
Accession:
GSM2936418
ID:
302936418
10.

WT -2

Organism:
Mus musculus
Source name:
murine embryonic fibroblast cell
Platform:
GPL21273
Series:
GSE109280
Download data: TXT
Sample
Accession:
GSM2936417
ID:
302936417
11.

WT -1

Organism:
Mus musculus
Source name:
murine embryonic fibroblast cell
Platform:
GPL21273
Series:
GSE109280
Download data: TXT
Sample
Accession:
GSM2936416
ID:
302936416
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Supplemental Content

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