GEO DataSets

(Submitter supplied) Arrays of regularly spaced nucleosomes dominate chromatin and are often phased, i.e., aligned at reference sites like active promoters. How distances between nucleosomes and distances between phasing sites and nucleosomes are determined remained unclear, specifically, the role of ATP dependent chromatin remodelers in it. Here, we used a genome-wide reconstitution system to probe how yeast remodelers generate phased nucleosome arrays. more...

Organism:

Saccharomyces cerevisiae; Escherichia coli; Schizosaccharomyces pombe

Type:

Genome binding/occupancy profiling by high throughput sequencing

Platforms:

GPL20045 GPL18085 GPL22681

450 Samples

Download data: BED, BW, CSV, RDS, TAB, TXT

(Submitter supplied) Acetaminophen (APAP) is a commonly used analgesic responsible for more than half of acute liver failure cases. Identification of previously unknown genetic risk factors would provide mechanistic insights and novel therapeutic targets for APAP-induced liver injury. This study used a genome-wide CRISPR-Cas9 screen to evaluate genes that are protective against, or cause susceptibility to, APAP-induced liver injury. more...

Organism:

Homo sapiens; Escherichia coli

Type:

Expression profiling by high throughput sequencing

Platforms:

GPL20045 GPL18460

12 Samples

Download data: TXT

(Submitter supplied) We report the genome-wide analysis from chromatin immunoprecipitated DNA (ChIP-sequencing) at very high resolution (about 50 millions reads) of the DNA binding pattern of ParBF (SopB) of plasmid F

Organism:

Escherichia coli

Type:

Genome binding/occupancy profiling by high throughput sequencing

Platform:

GPL20045

2 Samples

Download data: TXT