GEO DataSets

(Submitter supplied) Eukaryotic chromosomes replicate in a temporal order known as the replication-timing program. In mammals, replication timing is cell type-specific with at least half the genome switching replication timing during development, primarily in units of 400-800 kilobases ('replication domains;), whose positions are preserved in different cell types, conserved between species, and appear to confine long-range effects of chromosome rearrangements. more...

Organism:

Homo sapiens; Mus musculus

Type:

Other

25 related Platforms

993 Samples

Download data: BAM, BED, BIGWIG, BROADPEAK, NARROWPEAK, PAIR, TSV, TXT

(Submitter supplied) In multicellular organisms, developmental changes to replication timing occur in 400- 800 kb domains across half the genome. While clear examples of epigenetic control of replication timing have been described, a role for DNA sequence in mammalian replication timing has not been substantiated. To assess the role of DNA sequences in directing these changes, we profiled replication timing in mice carrying a genetically rearranged Human Chromosome 21 [Hsa21]. more...

Organism:

Homo sapiens; Mus musculus

Type:

Genome variation profiling by genome tiling array

Platforms:

GPL15225 GPL11620 GPL15656

6 Samples

Download data: PAIR, TXT

(Submitter supplied) Build: Hg18, NCBI 36 native array description file: 2006-09-22_HG18_CHR21_FT.ndf native array description file: 2006-09-22_HG18_CHR21_FT.pos Protocol: See www.nimblegen.com

Organism:

Homo sapiens

2 Series

4 Samples

Download data: NDF, POS