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Items: 1 to 20 of 623

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1.

RNA-seq analysis of blood transcriptomes from managed bottlenose dolphins in Waikoloa, Hawaii, USA

(Submitter supplied) Whole blood was collected as part of monthly veterinary checkups of bottlenose dolphins housed at Dolphing Quest in Waikoloa, Hawaii, USA. Gene expression from 5 samples was analyzed for comparison to the blood transcriptome of the beluga whale.
Organism:
Tursiops truncatus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL21538
5 Samples
Download data: FASTA, XLSX
Series
Accession:
GSE98627
ID:
200098627
2.

Transcriptomic features of Pecten maximus oocyte quality and maturation

(Submitter supplied) The king scallop Pecten maximus is a high valuable species of great interest in Europe for both fishery and aquaculture. However, hatchery production is a relatively new industry and it is still underdeveloped. Major hurdles are spawning control and gamete quality. In the present study, a total of 14 scallops were sampled in the bay of Brest (Brittany, France) to compare transcriptomic profiles of mature oocytes collected by spawning induction or by stripping. more...
Organism:
Pecten maximus
Type:
Expression profiling by array
Platform:
GPL22720
14 Samples
Download data: TXT
Series
Accession:
GSE90679
ID:
200090679
3.

Skin Transcriptomics of Common Bottlenose Dolphins (Tursiops truncatus) from the Northern Gulf of Mexico and Southeastern U.S. Atlantic Coasts

(Submitter supplied) Common bottlenose dolphins serve as sentinels for the health of their coastal environments as they are susceptible to health impacts from anthropogenic inputs through both direct exposure and food web magnification. Remote biopsy samples have been widely used to reveal contaminant burdens in free-ranging bottlenose dolphins, but do not address the health consequences of this exposure. To gain insight into whether remote biopsies can also identify health impacts associated with contaminant burdens, we employed RNA sequencing (RNA-seq) to interrogate the transcriptomes of remote skin biopsies from 116 bottlenose dolphins from the northern Gulf of Mexico and southeastern U.S. more...
Organism:
Tursiops truncatus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL21538
116 Samples
Download data: TXT, XLSX
Series
Accession:
GSE90941
ID:
200090941
4.

Seasonal Variation in the Skin Transcriptome of Bottlenose Dolphins (Tursiops truncatus)

(Submitter supplied) As apex predators, cetaceans are recognized as sentinels for the health of marine ecosystems. The ability to identify the impacts of anthropogenic contamination on the health of a species requires long term monitoring to establish baseline health parameters. This makes health measurements that can be sampled from free ranging animals highly desirable. In the current study, we investigate the utility of skin gene expression profiling to monitor the physiological, health, and contaminant exposure status in bottlenose dolphins. more...
Organism:
Tursiops truncatus
Type:
Expression profiling by array
Platform:
GPL18797
94 Samples
Download data: TXT
Series
Accession:
GSE58471
ID:
200058471
5.

RNA-seq analysis of seasonal and individual variation in blood transcriptomes of healthy captive bottlenose dolphins

(Submitter supplied) Four captive bottlenose dolpins housed in Kona, Hawaii, were serially sampled at approximately monthly intervals over the course of one year, in order to establish baseline information on the content and variation of the dolphin blood transcriptome.
Organism:
Tursiops truncatus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL21538
31 Samples
Download data: FASTA, PDF, XLS, XLSX
Series
Accession:
GSE78770
ID:
200078770
6.

TRANSCRIPTOMIC ANALYSIS OF BOTTLENOSE DOLPHIN (Tursiops truncatus) SKIN BIOPSIES TO ASSESS THE EFFECTS OF EMERGING CONTAMINANTS ON A TOP PREDATOR IN THE MEDITERRANEAN SEA

(Submitter supplied) To assess the impact of emerging contaminats on dolphin transcriptome
Organism:
Tursiops truncatus
Type:
Expression profiling by array
Platform:
GPL17696
8 Samples
Download data: TXT
Series
Accession:
GSE69917
ID:
200069917
7.

G-CSF mobilizes CD34+ regulatory monocytes that inhibit Graft-versus-Host Disease

(Submitter supplied) Administration of G-CSF mobilizes a unique population of CD11b+Ly6C+CD34+mature monocytes that can inhibit GVHD in murine models of BMT via an iNOS-dependent mechanism. The transcriptional profiles of flow sorted lineage-CD11b+CD34+ cells from G-CSF treated mice were compared with conventional splenic Ly6C+ and Ly6C- monocytes, progenitor cells and cultured myeloid-derived suppressor cells. Further comparisons were made with lineage-CD11b+CD34+ cells from G-CSF treated mice that had been grown in culture or that were derived from iNOS ko mice. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL16570
25 Samples
Download data: CEL
Series
Accession:
GSE65670
ID:
200065670
8.

SInsights into molecular features of Venerupis decussata oocytes: a microarray-based study.

(Submitter supplied) The European clam, Ruditapes decussatus (Linnaeus, 1758), is a bivalve mollusc of the family Veneridae native to the European Atlantic and Mediterranean coastal waters. Its production is exclusively based on natural recruitment, which is subject to high annual fluctuations due to adversely affected by pollution and other environmental factors. In the present study, oocytes from 15 females were collected in Ria de Aveiro (Western coast of Portugal) and microarray analysis was performed in order to investigate gene expression profiles characterizing naturally released oocytes and ovarian oocytes obtained by stripping. more...
Organism:
Ruditapes decussatus
Type:
Expression profiling by array
Platform:
GPL18284
15 Samples
Download data: TXT
Series
Accession:
GSE58906
ID:
200058906
9.

Determination and Inference of Eukaryotic Transcription Factor Sequence Specificity

(Submitter supplied) The DNA sequence preferences of the vast majority of eukaryotic transcription factors (TFs) are unknown. Using an approach designed to broadly sample both DNA-binding domain types and eukaryotic clades, we have determined DNA-binding motifs for 1,033 TFs from 131 diverse eukaryotes, encompassing 54 domain types. Closely related orthologs and paralogs typically have very similar sequence preferences; this property allows inference of motifs for roughly one third of the 166,851 known or predicted eukaryotic TFs. more...
Organism:
synthetic construct
Type:
Other
Platform:
GPL11260
2064 Samples
Download data: TXT
Series
Accession:
GSE53348
ID:
200053348
10.

Gene expression profile of human endothelial cells with or without nanoparticles

(Submitter supplied) To understand the the effect of poly(lactic-co-glycolic acid) nanoparticles (NPs) encapsulating a fluorine contrast agent on human umbilical vein endothelial cells (HUVECs), we have employed whole genome microarray expression profiling. The NPs used in this study were prepared in our lab. HUVECs were ordered from Lonza (Cat# C2517A). HUVECs were incubated with NPs for 4 hours. After 4 h, the cells were washed couple of times to remove the NPs and gene expression profiles were detected after 20 h (total time: 24 h) and 7 d in the absence of NPs. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL6480
9 Samples
Download data: TXT
Series
Accession:
GSE51661
ID:
200051661
11.

Gene expression profile of hematopoietic stem cells (CD34+ cells) with or without nanoparticles

(Submitter supplied) To understand the the effect of poly(lactic-co-glycolic acid) nanoparticles (NPs) encapsulating a fluorine contrast agent on hematopoietic stem cells (CD34+ fraction of umbilical cord blood mononuclear cells), we have employed whole genome microarray expr
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL6480
12 Samples
Download data: TXT
Series
Accession:
GSE51421
ID:
200051421
12.

Blood Transcriptome analysis of wild common bottlenose dolphins (Tursiops truncatus) from the South-East of the United States

(Submitter supplied) To validate the oligo array and to investigate the impact of the environmental stressors on dolphin health at transcriptomic level
Organism:
Tursiops truncatus
Type:
Expression profiling by array
Platform:
GPL17696
73 Samples
Download data: TXT
Series
Accession:
GSE50684
ID:
200050684
13.

Vibrio campbellii bioluminescence and its effect on gene expression and virulence

(Submitter supplied) The selective advantage of bioluminescence in bacterial cells that do not form symbiotic relationships with aquatic animals is still not known. Some evidence suggests that bioluminescence plays a role in DNA repair by a photoreactivation process (Czyz 2000) and that non-bioluminescent strains are less virulent than their bioluminescent isogenic counterparts (Ruwandeepika 2010). All hypotheses to date suggest bioluminescence associated or mediated changes in gene expression, yet the evidence for this does not exist. more...
Organism:
Vibrio campbellii ATCC BAA-1116; Vibrio campbellii
Type:
Expression profiling by array
Platform:
GPL10230
6 Samples
Download data: CEL
Series
Accession:
GSE34741
ID:
200034741
14.

Insulin resistance induced by physical inactivity is associated with multiple transcriptional changes in skeletal muscle in young men

(Submitter supplied) Rationale: Physical inactivity is a risk factor for insulin resistance. We examined the effect of nine days of bed rest on basal and insulin stimulated expression of genes potentially involved in insulin action by applying hypothesis-generating microarray in parallel with candidate gene real-time PCR approaches in 20 healthy, young men. Furthermore, we investigated whether bed rest affected DNA methylation in the promoter region of the peroxisome proliferator-activated receptor gamma coactivator 1 alpha (PPARGC1A) gene. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL6480
60 Samples
Download data: TXT
Series
Accession:
GSE24215
ID:
200024215
15.

Transcriptome Analysis of North Atlantic Right Whale Kidney Fibroblast Cell line exposed to cadmium

(Submitter supplied) An 8X15k oligonucleotide microarray was developed consisting of 2334 E. glacialis probes and 2166 Tursiops truncatus probes and used to measure the transcriptome level effects of right whale kidney fibroblast cells exposed to cadmium. Cells were exposed to three concentrations of cadmium chloride (CdCl2) for three exposure times. Cells exposed to 10-6M CdCl2 for 4 hours and 24 hours showed upregulated genes involved in protection from metal toxicity, oxidative stress, protein renaturation, apoptosis inhibition, and several regulators of cellular processes. more...
Organism:
Tursiops truncatus; Eubalaena glacialis
Type:
Expression profiling by array
Platform:
GPL8963
12 Samples
Download data: TXT
Series
Accession:
GSE17457
ID:
200017457
16.

Wild dolphin PBL analysis

(Submitter supplied) To determine what can the transcriptome tell us about populations of free-ranging bottlenose dolphins, Tursiops truncatus. Keywords: health assessment
Organism:
Tursiops truncatus
Type:
Expression profiling by array
Platform:
GPL6523
151 Samples
Download data: TXT
Series
Accession:
GSE10617
ID:
200010617
17.

Effects of capture-release events in wild dolphins: PBL analysis

(Submitter supplied) Goal: To determine the effects of capture-release events in wild dolphins (Tursiops truncatus). Methods: An analysis of the Peripheral Blood Leukocyte (PBL) transcriptome was conducted on a group of 20 animals. The samples were collected in 2 different locations along the US east coast (Charleston, SC; Indian River Lagoon, FL) and 2 blood samples were collected for each dolphin 1) immediately after the capture event (*pre*) and 2) just before the animal was released (*post*). more...
Organism:
Tursiops truncatus
Type:
Expression profiling by array
Platform:
GPL3609
40 Samples
Download data: TXT
Series
Accession:
GSE7691
ID:
200007691
18.

Profiling of Dolphin Skin Cells

(Submitter supplied) 3 technical replicates from Wild Dolphin PBL Keywords: Immune and stress response analysis
Organism:
Tursiops truncatus
Type:
Expression profiling by array
Platform:
GPL3609
8 Samples
Download data
Series
Accession:
GSE4580
ID:
200004580
19.

Agilent-028889 Tursiops truncatus AM_v1 [Probe name version]

(Submitter supplied) Arrays of this design have barcodes that begin with 16028889 or 2528889. Orientation: Features are numbered numbered Left-to-Right, Top-to-Bottom as scanned by an Agilent scanner (barcode on the left, DNA on the back surface, scanned through the glass), matching the FeatureNum output from Agilent's Feature Extraction software. Protocol: see manufacturer's web site at http://www.agilent.com/
Organism:
Tursiops truncatus
1 Series
94 Samples
Download data
Platform
Accession:
GPL18797
ID:
100018797
20.

Illumina HiSeq 2500 (Tursiops truncatus)

Organism:
Tursiops truncatus
3 Series
152 Samples
Download data
Platform
Accession:
GPL21538
ID:
100021538
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