ClinVar for PubMed (Select 23414587) - ClinVar

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Items: 20

	Variation	Gene (Protein Change)	Type (Consequence)	Condition	Classification, Review status
Select item 375877	NM_002524.5(NRAS):c.38G>C (p.Gly13Ala)	NRAS (G13A)	Single nucleotide variant (missense variant)	Melanoma	GPathogenic
Select item 375876	NM_002524.5(NRAS):c.38G>T (p.Gly13Val)	NRAS (G13V)	Single nucleotide variant (missense variant)	Neoplasm of the large intestine +10 more	GPathogenic/Likely pathogenic
Select item 375875	NM_002524.5(NRAS):c.181C>G (p.Gln61Glu)	NRAS (Q61E)	Single nucleotide variant (missense variant)	Melanoma	GPathogenic
Select item 375874	NM_002524.5(NRAS):c.182A>T (p.Gln61Leu)	NRAS (Q61L)	Single nucleotide variant (missense variant)	RASopathy	GUncertain significance
Select item 375873	NM_002524.5(NRAS):c.182_183delinsGG (p.Gln61Arg)	NRAS (Q61R)	Indel (missense variant)	Melanoma	GPathogenic
Select item 375872	NM_002524.5(NRAS):c.182_183delinsTG (p.Gln61Leu)	NRAS (Q61L)	Indel (missense variant)	Melanoma	GPathogenic
Select item 375871	NM_002524.5(NRAS):c.183A>C (p.Gln61His)	NRAS (Q61H)	Single nucleotide variant (missense variant)	Melanoma +2 more	GPathogenic/Likely pathogenic
Select item 373003	NM_002524.5(NRAS):c.183A>T (p.Gln61His)	NRAS (Q61H)	Single nucleotide variant (missense variant)	Noonan syndrome and Noonan-related syndrome +1 more	GConflicting classifications of pathogenicity
Select item 280409	NM_002524.5(NRAS):c.182A>C (p.Gln61Pro)	NRAS (Q61P)	Single nucleotide variant (missense variant)	not provided	GPathogenic
Select item 219097	NM_002524.5(NRAS):c.35G>C (p.Gly12Ala)	NRAS (G12A)	Single nucleotide variant (missense variant)	Noonan syndrome and Noonan-related syndrome +3 more	GPathogenic/Likely pathogenic
Select item 177778	NM_002524.5(NRAS):c.34G>A (p.Gly12Ser)	NRAS (G12S)	Single nucleotide variant (missense variant)	Noonan syndrome and Noonan-related syndrome +3 more	GPathogenic
Select item 73058	NM_002524.5(NRAS):c.181C>A (p.Gln61Lys)	NRAS (Q61K)	Single nucleotide variant (missense variant)	Large congenital melanocytic nevus +2 more	GConflicting classifications of pathogenicity
Select item 40471	NM_002524.5(NRAS):c.37G>T (p.Gly13Cys)	NRAS (G13C)	Single nucleotide variant (missense variant)	Melanoma	GPathogenic
Select item 40470	NM_002524.5(NRAS):c.35G>T (p.Gly12Val)	NRAS (G12V)	Single nucleotide variant (missense variant)	not provided +2 more	GPathogenic/Likely pathogenic
Select item 40469	NM_002524.5(NRAS):c.34G>C (p.Gly12Arg)	NRAS (G12R)	Single nucleotide variant (missense variant)	Noonan syndrome 6 +2 more	GPathogenic
Select item 40468	NM_002524.5(NRAS):c.34G>T (p.Gly12Cys)	NRAS (G12C)	Single nucleotide variant (missense variant)	not provided	GPathogenic
Select item 39648	NM_002524.5(NRAS):c.35G>A (p.Gly12Asp)	NRAS (G12D)	Single nucleotide variant (missense variant)	NRAS-related condition +5 more	GPathogenic/Likely pathogenic
Select item 13901	NM_002524.5(NRAS):c.38G>A (p.Gly13Asp)	NRAS (G13D)	Single nucleotide variant (missense variant)	Acute megakaryoblastic leukemia in down syndrome +2 more	GPathogenic/Likely pathogenic
Select item 13900	NM_002524.5(NRAS):c.182A>G (p.Gln61Arg)	NRAS (Q61R)	Single nucleotide variant (missense variant)	Large congenital melanocytic nevus +3 more	GConflicting classifications of pathogenicity
Select item 13899	NM_002524.5(NRAS):c.37G>C (p.Gly13Arg)	NRAS (G13R)	Single nucleotide variant (missense variant)	Noonan syndrome 6	GLikely pathogenic

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Items: 20