Pharmacogenomics Knowledge Base (Stanford University), PharmGKB

General information

Pharmacogenomics Knowledge Base, PharmGKB
Stanford University
Stanford
California
United States - 94305-4125
https://www.pharmgkb.org
Organization ID: 500295

Expert panel documentation

Personnel

Assertion criteria

Level: Expert panel

Summary of submissions to ClinVar

Total submissions: 744

Gene

GeneSubmissionsLast Updated
ABCB112Jun 18, 2018
ABCC41Jun 18, 2018
ABCC86Jun 14, 2019
ABCG22Jun 18, 2018
ACE1Jun 18, 2018
ACYP21Jun 18, 2018
ADD11Jun 18, 2018
ADORA2A1Jun 18, 2018
ADORA2A-AS11Jun 18, 2018
ADRB22Jun 18, 2018
ANKK16Jun 18, 2018
APOA53Jun 18, 2018
APOE1Jun 18, 2018
ATIC1Jun 18, 2018
C11orf651Jun 18, 2018
C8orf341Jun 18, 2018
CACNA1S14Jun 14, 2019
CALU1Jun 18, 2018
CBR31Jun 18, 2018
CBR3-AS11Jun 18, 2018
CCHCR11Jun 18, 2018
CDCA31Jun 18, 2018
CEP72-DT1Jun 18, 2018
CES11Jun 18, 2018
CETP1Jun 18, 2018
CFTR38Jun 18, 2018
CFTR-AS13Jun 18, 2018
CHRNA32Jun 18, 2018
CHRNA51Jun 14, 2019
CHRNB21Jun 18, 2018
COL22A11Jun 18, 2018
COMT9Jun 14, 2019
COQ23Jun 18, 2018
CRHR15Jun 18, 2018
CRHR22Jun 18, 2018
CYP19A110Jun 18, 2018
CYP2B611Jun 18, 2018
CYP2C199Jun 18, 2018
CYP2C81Jun 18, 2018
CYP2C915Jun 18, 2018
CYP2D69Jun 18, 2018
CYP3A41Jun 18, 2018
CYP3A56Jun 18, 2018
CYP4F24Jun 18, 2018
DPP61Jun 18, 2018
DPYD19Jun 14, 2019
DRD28Jun 18, 2018
DYNC2H12Jun 18, 2018
EGF1Jun 18, 2018
EGFR6Jun 18, 2018
EGFR-AS12Jun 18, 2018
ENOSF12Jun 18, 2018
EPHX12Jun 18, 2018
ERCC18Jun 18, 2018
F51Jun 18, 2018
FCGR2A1Jun 18, 2018
FCGR3A2Jun 18, 2018
FDPS1Jun 18, 2018
FKBP57Jun 18, 2018
FLT31Jun 18, 2018
G6PD1Jun 18, 2018
GATM2Jun 18, 2018
GGCX1Jun 18, 2018
GNB31Jun 18, 2018
GP1BA1Jun 18, 2018
GRIK41Jun 18, 2018
GSTP14Jun 18, 2018
HAS31Jun 18, 2018
HMGCR3Jun 18, 2018
HTR1A1Jun 18, 2018
HTR2A3Jun 18, 2018
HTR2C5Jun 18, 2018
IFNL310Jun 18, 2018
IFNL46Jun 18, 2018
ITPA4Jun 18, 2018
KCNJ116Jun 14, 2019
KIF62Jun 18, 2018
KRAS2Jun 18, 2018
LINC02210-CRHR15Jun 18, 2018
LOC1101214721Jun 18, 2018
LOC1103663541Jun 18, 2018
LOC1105995703Jun 18, 2018
LOC1116744726Jun 18, 2018
LOC1116744756Jun 18, 2018
LOC1136338771Jun 18, 2018
LOC1136641061Jun 18, 2018
LPA1Jun 18, 2018
LTC4S1Jun 18, 2018
MC4R10Jun 18, 2018
MIR4713HG10Jun 18, 2018
MT-RNR121Jun 18, 2018
MT-TS17Jun 18, 2018
MTHFR3Jun 18, 2018
MTRR1Jun 18, 2018
NAT22Jun 18, 2018
NEDD4L2Jun 18, 2018
NQO11Jun 18, 2018
NT5C21Jun 18, 2018
NUDT152Jun 18, 2018
OPRD11Jun 14, 2019
OPRM110Jun 18, 2018
PIRC6610Jun 18, 2018
PNPLA35Jun 18, 2018
POLR1G3Jun 18, 2018
PRKCA1Jun 18, 2018
PTGFR1Jun 18, 2018
PTGS11Jun 18, 2018
RYR1312Jul 30, 2021
SCN1A4Jun 18, 2018
SEMA3C1Jun 18, 2018
SLC28A32Jun 18, 2018
SLCO1B18Jun 18, 2018
SOD21Jun 18, 2018
SPECC1L-ADORA2A1Jun 18, 2018
TANC16Jun 18, 2018
TCF7L21Jun 18, 2018
TMEM431Jun 18, 2018
TNF4Jun 18, 2018
TP535Jun 18, 2018
TXNRD21Jun 18, 2018
TYMS2Jun 18, 2018
UGT1A8Jun 18, 2018
UGT1A16Jun 18, 2018
UGT1A108Jun 18, 2018
UGT1A36Jun 18, 2018
UGT1A47Jun 18, 2018
UGT1A57Jun 18, 2018
UGT1A67Jun 18, 2018
UGT1A77Jun 18, 2018
UGT1A88Jun 18, 2018
UGT1A98Jun 18, 2018
UGT2B101Jun 18, 2018
UGT2B152Jun 18, 2018
UMPS4Jun 18, 2018
VDR1Jun 18, 2018
VKORC118Jun 18, 2018
XPC1Jun 18, 2018
XRCC15Jun 18, 2018
YEATS41Jun 18, 2018
ZSCAN256Jun 18, 2018

Condition

NameSubmissionsLast Updated
Alkylating Agents, anthracyclines and related substances, fluorouracil, and Platinum compounds response - Efficacy1Jun 18, 2018
Antiinflammatory agents, non-steroids response - Toxicity/ADR1Jun 18, 2018
Bisphosphonates response - Efficacy1Jun 18, 2018
Drugs used in opioid dependence response - Dosage, Efficacy, Metabolism/PK1Jun 18, 2018
HMG CoA reductase inhibitors response - Efficacy2Jun 18, 2018
Ivacaftor response1Jun 18, 2018
Platinum compounds response - Efficacy1Jun 18, 2018
Platinum compounds response - Efficacy, Toxicity/ADR1Jun 18, 2018
Platinum compounds response - Toxicity/ADR3Jun 18, 2018
Pyrimidine analogues response - Toxicity/ADR1Jun 18, 2018
Pyrimidine analogues response - Toxicity/ADR, Metabolism/PK2Jun 18, 2018
SN-38 response - Other3Jun 18, 2018
Selective serotonin reuptake inhibitors response - Efficacy3Jun 18, 2018
Tumor necrosis factor alpha (TNF-alpha) inhibitors response - Efficacy1Jun 18, 2018
acenocoumarol response - Dosage4Jun 18, 2018
acenocoumarol response - Dosage, Toxicity/ADR1Jun 18, 2018
acenocoumarol response - Toxicity/ADR2Jun 18, 2018
adalimumab response - Efficacy1Jun 18, 2018
alfentanil response - Dosage, Efficacy, Metabolism/PK1Jun 18, 2018
allopurinol response - Dosage, Efficacy1Jun 18, 2018
amikacin response - Toxicity/ADR3Jun 18, 2018
aminoglycoside antibacterials response - Toxicity/ADR3Jun 18, 2018
amisulpride response - Toxicity/ADR1Jun 18, 2018
amitriptyline response - Dosage, Toxicity/ADR1Jun 18, 2018
amitriptyline response - Efficacy1Jun 18, 2018
anastrozole response - Efficacy1Jun 18, 2018
anthracyclines and related substances response - Toxicity/ADR4Jun 18, 2018
antidepressants response - Dosage, Toxicity/ADR1Jun 18, 2018
antidepressants response - Efficacy3Jun 18, 2018
antiepileptics response - Efficacy1Jun 18, 2018
antineoplastic agents response - Efficacy, Toxicity/ADR1Jun 18, 2018
antipsychotics response - Toxicity/ADR5Jun 18, 2018
aripiprazole response - Toxicity/ADR1Jun 18, 2018
asparaginase response - Toxicity/ADR1Jun 18, 2018
aspirin response - Efficacy2Jun 18, 2018
aspirin response - Toxicity/ADR1Jun 18, 2018
ataluren response - Efficacy3Jun 18, 2018
atazanavir and ritonavir response - Toxicity/ADR1Jun 18, 2018
atazanavir response - Other1Jun 18, 2018
atorvastatin response - Efficacy3Jun 18, 2018
atorvastatin response - Toxicity/ADR1Jun 18, 2018
azathioprine response - Dosage, Toxicity/ADR1Jun 18, 2018
azathioprine response - Toxicity/ADR1Jun 18, 2018
boceprevir response - Efficacy1Jun 18, 2018
boceprevir, peginterferon alfa-2a, peginterferon alfa-2b, ribavirin, simeprevir, and telaprevir response - Efficacy1Jun 18, 2018
budesonide response - Efficacy1Jun 18, 2018
buprenorphine response - Dosage1Jun 18, 2018
buprenorphine response - Dosage, Efficacy, Metabolism/PK1Jun 18, 2018
buprenorphine response - Efficacy1Jun 14, 2019
bupropion response - Efficacy1Jun 18, 2018
caffeine response - Toxicity/ADR1Jun 18, 2018
capecitabine response - Efficacy1Jun 18, 2018
capecitabine response - Toxicity/ADR3Jun 14, 2019
capecitabine response - Toxicity/ADR, Metabolism/PK2Jun 18, 2018
captopril response - Efficacy1Jun 18, 2018
carbamazepine response - Dosage3Jun 18, 2018
carbamazepine response - Efficacy1Jun 18, 2018
carboplatin response - Efficacy2Jun 18, 2018
carboplatin response - Efficacy, Toxicity/ADR1Jun 18, 2018
carboplatin, docetaxel, erlotinib, gemcitabine, and paclitaxel response - Efficacy1Jun 18, 2018
celecoxib response - Dosage1Jun 18, 2018
celecoxib response - Toxicity/ADR1Jun 18, 2018
cerivastatin response - Toxicity/ADR1Jun 18, 2018
cetuximab response - Dosage1Jun 18, 2018
cetuximab response - Efficacy1Jun 18, 2018
chlorproguanil and dapsone response - Toxicity/ADR1Jun 18, 2018
cisplatin response - Efficacy1Jun 18, 2018
cisplatin response - Efficacy, Toxicity/ADR2Jun 18, 2018
cisplatin response - Toxicity/ADR4Jun 18, 2018
citalopram response - Efficacy3Jun 18, 2018
citalopram response - Metabolism/PK1Jun 18, 2018
clomipramine response - Dosage, Toxicity/ADR1Jun 18, 2018
clomipramine response - Efficacy1Jun 18, 2018
clopidogrel response - Dosage, Efficacy, Toxicity/ADR1Jun 18, 2018
clopidogrel response - Efficacy2Jun 18, 2018
clopidogrel response - Efficacy, Toxicity/ADR2Jun 18, 2018
clozapine response - Toxicity/ADR3Jun 18, 2018
cocaine response - Toxicity/ADR1Jun 18, 2018
corticosteroids response - Efficacy1Jun 18, 2018
cyclophosphamide and epirubicin response - Efficacy, Toxicity/ADR1Jun 18, 2018
cyclophosphamide response - Efficacy2Jun 18, 2018
cyclophosphamide response - Efficacy, Toxicity/ADR1Jun 18, 2018
cyclophosphamide response - Toxicity/ADR2Jun 18, 2018
cyclosporine response - Dosage, Metabolism/PK1Jun 18, 2018
daunorubicin response - Toxicity/ADR1Jun 18, 2018
desflurane response - Toxicity1Jul 30, 2021
desflurane response - Toxicity/ADR45Jun 14, 2019
desipramine response - Dosage, Toxicity/ADR1Jun 18, 2018
diclofenac response - Toxicity/ADR1Jun 18, 2018
digoxin response - Other1Jun 18, 2018
diuretics response - Efficacy1Jun 18, 2018
docetaxel response - Efficacy1Jun 18, 2018
doxepin response - Dosage, Toxicity/ADR1Jun 18, 2018
doxorubicin response - Efficacy1Jun 18, 2018
efavirenz response - Dosage1Jun 18, 2018
efavirenz response - Metabolism/PK4Jun 18, 2018
efavirenz response - Toxicity/ADR1Jun 18, 2018
enflurane response - Toxicity1Jul 30, 2021
enflurane response - Toxicity/ADR45Jun 14, 2019
epirubicin response - Efficacy1Jun 18, 2018
erlotinib response - Efficacy2Jun 18, 2018
escitalopram response - Metabolism/PK1Jun 18, 2018
etanercept response - Efficacy1Jun 18, 2018
ethambutol, isoniazid, pyrazinamide, and rifampin response - Toxicity/ADR1Jun 18, 2018
ethambutol, isoniazid, pyrazinamide, and rifampin response - Toxicity/ADR, Metabolism/PK1Jun 18, 2018
ethanol response - Toxicity/ADR2Jun 18, 2018
etoposide response - Toxicity/ADR1Jun 18, 2018
exemestane response - Efficacy1Jun 18, 2018
fentanyl response - Dosage1Jun 18, 2018
fentanyl response - Dosage, Efficacy1Jun 18, 2018
fentanyl response - Dosage, Efficacy, Metabolism/PK1Jun 18, 2018
fluorouracil and oxaliplatin response - Efficacy1Jun 18, 2018
fluorouracil response - Efficacy2Jun 18, 2018
fluorouracil response - Efficacy, Toxicity/ADR1Jun 18, 2018
fluorouracil response - Other4Jun 14, 2019
fluorouracil response - Toxicity/ADR4Jun 14, 2019
fluorouracil response - Toxicity/ADR, Metabolism/PK2Jun 18, 2018
fluoxetine response - Efficacy1Jun 18, 2018
fluticasone propionate response - Efficacy1Jun 18, 2018
fluticasone/salmeterol response - Efficacy1Jun 18, 2018
furosemide and spironolactone response - Efficacy1Jun 18, 2018
gefitinib response - Efficacy3Jun 18, 2018
gemcitabine response - Other1Jun 18, 2018
gentamicin response - Toxicity/ADR3Jun 18, 2018
glibenclamide response - Efficacy1Jun 14, 2019
gliclazide response - Efficacy1Jun 14, 2019
glimepiride response - Efficacy1Jun 14, 2019
glipizide response - Efficacy1Jun 14, 2019
gliquidone response - Efficacy1Jun 14, 2019
haloperidol response - Toxicity/ADR1Jun 18, 2018
halothane response - Toxicity1Jul 30, 2021
halothane response - Toxicity/ADR45Jun 14, 2019
heroin response - Dosage, Efficacy, Metabolism/PK1Jun 18, 2018
hmg coa reductase inhibitors response - Efficacy, Toxicity/ADR1Jun 18, 2018
hmg coa reductase inhibitors response - Toxicity/ADR3Jun 18, 2018
hmg coa reductase inhibitors response - Toxicity/ADR, Metabolism/PK1Jun 18, 2018
hormonal contraceptives for systemic use response - Toxicity/ADR1Jun 18, 2018
hydrochlorothiazide response - Efficacy3Jun 18, 2018
imipramine response - Dosage, Toxicity/ADR1Jun 18, 2018
infliximab response - Efficacy1Jun 18, 2018
interferon alfa-2b, recombinant and ribavirin response - Dosage, Toxicity/ADR1Jun 18, 2018
interferons, peginterferon alfa-2a, peginterferon alfa-2b, and ribavirin response - Efficacy1Jun 18, 2018
irinotecan response - Other1Jun 18, 2018
irinotecan response - Toxicity/ADR3Jun 18, 2018
isoflurane response - Toxicity1Jul 30, 2021
isoflurane response - Toxicity/ADR45Jun 14, 2019
ivacaftor / lumacaftor response - Efficacy1Jun 18, 2018
ivacaftor response - Efficacy33Jun 18, 2018
kanamycin response - Toxicity/ADR3Jun 18, 2018
lamotrigine response - Other1Jun 18, 2018
latanoprost response - Efficacy1Jun 18, 2018
leucovorin response - Toxicity/ADR1Jun 18, 2018
lorazepam response - Other1Jun 18, 2018
lovastatin response - Efficacy1Jun 18, 2018
meperidine response - Dosage1Jun 18, 2018
mercaptopurine response - Dosage, Toxicity/ADR1Jun 18, 2018
metformin response - Efficacy1Jun 18, 2018
methadone response - Dosage1Jun 18, 2018
methadone response - Dosage, Efficacy2Jun 14, 2019
methotrexate response - Dosage, Efficacy, Toxicity/ADR1Jun 18, 2018
methotrexate response - Efficacy1Jun 18, 2018
methotrexate response - Toxicity/ADR3Jun 18, 2018
methoxyflurane response - Toxicity1Jul 30, 2021
methoxyflurane response - Toxicity/ADR45Jun 14, 2019
mirtazapine response - Efficacy1Jun 18, 2018
morphine response - Dosage1Jun 18, 2018
morphine response - Dosage, Efficacy2Jun 14, 2019
morphine response - Dosage, Efficacy, Metabolism/PK1Jun 18, 2018
naloxone response - Efficacy1Jun 18, 2018
neomycin response - Toxicity/ADR3Jun 18, 2018
nevirapine response - Other2Jun 18, 2018
nevirapine response - Toxicity/ADR3Jun 18, 2018
nicotine response - Efficacy1Jun 18, 2018
nicotine response - Efficacy, Toxicity/ADR1Jun 18, 2018
nicotine response - Metabolism/PK1Jun 18, 2018
nicotine response - Toxicity/ADR2Jun 14, 2019
nicotine response - Toxicity/ADR, Metabolism/PK1Jun 18, 2018
nortriptyline response - Dosage, Toxicity/ADR1Jun 18, 2018
olanzapine response - Toxicity/ADR3Jun 18, 2018
ondansetron response - Efficacy2Jun 18, 2018
opioids response - Dosage1Jun 18, 2018
opioids response - Dosage, Efficacy2Jun 14, 2019
opioids response - Dosage, Efficacy, Metabolism/PK1Jun 18, 2018
oxaliplatin response - Efficacy1Jun 18, 2018
oxaliplatin response - Efficacy, Toxicity/ADR1Jun 18, 2018
oxazepam response - Other1Jun 18, 2018
oxycodone response - Dosage, Efficacy2Jun 14, 2019
paclitaxel response - Efficacy1Jun 18, 2018
paclitaxel response - Efficacy, Toxicity/ADR1Jun 18, 2018
paliperidone response - Toxicity/ADR1Jun 18, 2018
panitumumab response - Dosage1Jun 18, 2018
paroxetine response - Efficacy2Jun 18, 2018
peginterferon alfa-2a response - Efficacy1Jun 18, 2018
peginterferon alfa-2a, peginterferon alfa-2b, and ribavirin response - Efficacy1Jun 18, 2018
peginterferon alfa-2a, peginterferon alfa-2b, ribavirin, and telaprevir response - Efficacy2Jun 18, 2018
peginterferon alfa-2b and ribavirin response - Efficacy1Jun 18, 2018
peginterferon alfa-2b and ribavirin response - Toxicity/ADR2Jun 18, 2018
peginterferon alfa-2b response - Efficacy2Jun 18, 2018
pentazocine response - Dosage1Jun 18, 2018
phenprocoumon response - Dosage4Jun 18, 2018
phenytoin response - Dosage1Jun 18, 2018
platinum response - Efficacy1Jun 18, 2018
platinum response - Efficacy, Toxicity/ADR1Jun 18, 2018
platinum response - Toxicity/ADR1Jun 18, 2018
pravastatin response - Efficacy3Jun 18, 2018
pravastatin response - Metabolism/PK1Jun 18, 2018
prednisolone response - Toxicity/ADR1Jun 18, 2018
quetiapine response - Toxicity/ADR1Jun 18, 2018
radiotherapy response - Efficacy1Jun 18, 2018
radiotherapy response - Toxicity/ADR6Jun 18, 2018
remifentanil response - Dosage, Efficacy1Jun 14, 2019
ribavirin response - Efficacy2Jun 18, 2018
risperidone response - Efficacy1Jun 18, 2018
risperidone response - Toxicity/ADR3Jun 18, 2018
rituximab response - Efficacy1Jun 18, 2018
rosiglitazone response - Metabolism/PK1Jun 18, 2018
rosuvastatin response - Efficacy1Jun 18, 2018
rosuvastatin response - Other1Jun 18, 2018
rosuvastatin response - Toxicity/ADR1Jun 18, 2018
salbutamol response - Efficacy3Jun 18, 2018
salmeterol response - Efficacy1Jun 18, 2018
selective beta-2-adrenoreceptor agonists response - Efficacy1Jun 18, 2018
sevoflurane response - Toxicity1Jul 30, 2021
sevoflurane response - Toxicity/ADR45Jun 14, 2019
sildenafil response - Efficacy1Jun 18, 2018
simvastatin acid response - Metabolism/PK1Jun 18, 2018
simvastatin response - Efficacy3Jun 18, 2018
simvastatin response - Toxicity/ADR3Jun 18, 2018
sirolimus response - Dosage1Jun 18, 2018
sirolimus response - Metabolism/PK1Jun 18, 2018
streptomycin response - Toxicity/ADR3Jun 18, 2018
succinylcholine response - Toxicity1Jul 30, 2021
succinylcholine response - Toxicity/ADR45Jun 14, 2019
sufentanil response - Dosage, Efficacy1Jun 14, 2019
sulfonamides, urea derivatives response - Efficacy2Jun 14, 2019
sunitinib response - Toxicity/ADR1Jun 18, 2018
tacrolimus response (donor genotype) - Dosage, Metabolism/PK1Jun 18, 2018
tacrolimus response (recipient genotype) - Dosage, Metabolism/PK1Jun 18, 2018
tacrolimus response - Dosage1Jun 18, 2018
tacrolimus response - Efficacy1Jun 18, 2018
tamoxifen response - Efficacy1Jun 18, 2018
tamoxifen response - Efficacy, Toxicity/ADR1Jun 18, 2018
tegafur response - Toxicity/ADR2Jun 18, 2018
tegafur response - Toxicity/ADR, Metabolism/PK2Jun 18, 2018
tenofovir response - Metabolism/PK1Jun 18, 2018
tobramycin response - Toxicity/ADR3Jun 18, 2018
tramadol response - Dosage, Efficacy2Jun 14, 2019
tramadol response - Dosage, Efficacy, Metabolism/PK1Jun 18, 2018
trastuzumab response - Efficacy2Jun 18, 2018
triamcinolone response - Efficacy1Jun 18, 2018
trimipramine response - Dosage, Toxicity/ADR1Jun 18, 2018
venlafaxine response - Efficacy1Jun 18, 2018
vincristine response - Toxicity/ADR2Jun 18, 2018
volatile anesthetics response - Toxicity/ADR4Jun 14, 2019
warfarin response - Dosage19Jun 18, 2018
warfarin response - Dosage, Toxicity/ADR1Jun 18, 2018
warfarin response - Efficacy1Jun 18, 2018
warfarin response - Efficacy, Toxicity/ADR1Jun 18, 2018
warfarin response - Other1Jun 18, 2018
warfarin response - Toxicity/ADR2Jun 18, 2018
ziprasidone response - Toxicity/ADR1Jun 18, 2018
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