ClinVar

NM_004985.5(KRAS):c.34G>A (p.Gly12Ser)

Gene:

KRAS:KRAS proto-oncogene, GTPase [Gene - OMIM - HGNC]

Variant type:

single nucleotide variant

Cytogenetic location:

12p12.1

Genomic location:

• Chr12: 25245351 (on Assembly GRCh38)
• Chr12: 25398285 (on Assembly GRCh37)

Preferred name:

NM_004985.5(KRAS):c.34G>A (p.Gly12Ser)

HGVS:

• NC_000012.12:g.25245351C>T
• NG_007524.2:g.10653G>A
• NM_001369786.1:c.34G>A
• NM_001369787.1:c.34G>A
• NM_004985.5:c.34G>AMANE SELECT
• NM_033360.4:c.34G>A
• NP_001356715.1:p.Gly12Ser
• NP_001356716.1:p.Gly12Ser
• NP_004976.2:p.Gly12Ser
• NP_203524.1:p.Gly12Ser
• LRG_344t1:c.34G>A
• LRG_344t2:c.34G>A
• LRG_344:g.10653G>A
• LRG_344p1:p.Gly12Ser
• LRG_344p2:p.Gly12Ser
• NC_000012.11:g.25398285C>T
• NG_007524.1:g.10570G>A
• NM_004985.3:c.34G>A
• P01116:p.Gly12Ser
• c.34G>A

This HGVS expression did not pass validation

Protein change:

G12S; GLY12SER

Links:

UniProtKB: P01116#VAR_016028; OMIM: 190070.0007; dbSNP: rs121913530

NCBI 1000 Genomes Browser:

rs121913530

Molecular consequence:

• NM_001369786.1:c.34G>A - missense variant - [Sequence Ontology: SO:0001583]
• NM_001369787.1:c.34G>A - missense variant - [Sequence Ontology: SO:0001583]
• NM_004985.5:c.34G>A - missense variant - [Sequence Ontology: SO:0001583]
• NM_033360.4:c.34G>A - missense variant - [Sequence Ontology: SO:0001583]