4MQY


Conserved Protein Domain Family
lpxC

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TIGR00325: lpxC 
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UDP-3-0-acyl N-acetylglucosamine deacetylase
UDP-3-O-(R-3-hydroxymyristoyl)-GlcNAc deacetylase from E. coli , LpxC, was previously designated EnvA. This enzyme is involved in lipid-A precursor biosynthesis. It is essential for cell viability. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides]
Statistics
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PSSM-Id: 273014
Aligned: 5 rows
Threshold Bit Score: 455.445
Created: 7-Oct-2014
Updated: 25-Oct-2021
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
4MQY_A   2 IKQRTLKRIVQATGVGLHTGKKVTLTLRPAPANTGVIYRRTDLNPPVDFPADAKSVRDTMLCTCLVNEhDVRISTVEHLN 81  Escherichia coli BW2952
P45070   2 IKQRTLKQSIKVTGVGLHSGEKVTLTLRPAMPNTGVVYYRTDLNPAVAFPADPNSVRDTMLCTALINEqGVRISTVEHLN 81  Haemophilus influenza...
O25692   1 MKQTTINHSVELVGIGLHKGVPVKLVLEPLGENQGIVFYRSDLG--VNLPLKPENIVDTKMATVLGKD-NARISTIEHLL 77  Helicobacter pylori 2...
P72988   1 -MGHTIKAPLTVQGVGLHSGVETTVTLCPVAAGKGRYFQRVDLPKKPIIPADLTWVREAMLSTELGEP-GATIRTVEHLL 78  Synechocystis sp. PCC...
P07652   2 IKQRTLKRIVQATGVGLHTGKKVTLTLRPAPANTGVIYRRTDLNPPVDFPADAKSVRDTMLCTCLVNEhDVRISTVEHLN 81  Escherichia coli
4MQY_A  82 AALAGLGIDNIVIEVNAPEIPIMDGSAAPFVYLLLDAGIDELN--CAKKFVRIKETVRVEDGDKWAEFKPYNGFSLDFTI 159 Escherichia coli BW2952
P45070  82 AALAGLGIDNIIIEVDAPEIPIMDGSASPFIYLLLDAGIEEQN--AAKKFIRIKQYVRVEDGDKWAEFKPYNGFRLDFTI 159 Haemophilus influenza...
O25692  78 SAVHAYGIDNLKISVDNEEIPIMDGSALTYCMLLDEAGIKELD--APKKVMEIKQAVEIRESDKFVKIEPDSQLSLNFTI 155 Helicobacter pylori 2...
P72988  79 ATLVALDIGDLRIEVNGPEVPLLDGSALSWLTAIAKVGTRPRSkkSQDQPIVITDPLTCQLEDAFVAAFPCATTRFSYGV 158 Synechocystis sp. PCC...
P07652  82 AALAGLGIDNIVIEVNAPEIPIMDGSAAPFVYLLLDAGIDELN--CAKKFVRIKETVRVEDGDKWAEFKPYNGFSLDFTI 159 Escherichia coli
4MQY_A 160 DFNHPAIDSsnQRYAMNFSADAFMRQISRARTFGFMRDIEYLQSRGLCLGGSFDCAIVVDDYRVLNEDGLRFEDEFVRHK 239 Escherichia coli BW2952
P45070 160 DFDHPAIGKdvRNYEMNFSAQAFVHQISRARTFGFMKDIEYLQSQGLVLGGSLDNAIVLDDYRILNEDGLRFKDELVRHK 239 Haemophilus influenza...
O25692 156 DFNHPVIAK--QAHHFVFSKTAYKEQVAKARTFGFLQEVNYLRSIGLAKGGSLNNCIVLDENSILNKEGLRCEKEFVCHK 233 Helicobacter pylori 2...
P72988 159 DYPYLPIGK--QWYTWEPDQENFATAIAPARTFGFADQIEKLRQAGLIKGGSLENALVCDKEKWLNPP-LRFPDEPVRHK 235 Synechocystis sp. PCC...
P07652 160 DFNHPAIDSsnQRYAMNFSADAFMRQISRARTFGFMRDIEYLQSRGLCLGGSFDCAIVVDDYRVLNEDGLRFEDEFVRHK 239 Escherichia coli
4MQY_A 240 MLDAIGDLFMCGHNIIGAFTAYKSGHALNNKLLQAVLAKQEAWEYVTFQDDAELPLAFKAPS 301 Escherichia coli BW2952
P45070 240 MLDAIGDLYMAGYNIIGDFKAYKSGHGLNNKLLRAVLANQEAWEFVTFEDKAQVPQGYVAPV 301 Haemophilus influenzae Rd KW20
O25692 234 ILDAMGDLMVLGMPVMGKYTSFSGSHKLNSMLVKAILADAKNYEVLIAADPAKEFALQKAFA 295 Helicobacter pylori 26695
P72988 236 LLDLLGDLSLLGKIPQAHFVAYKASHKLHTQLAQKIADTYR--------------------- 276 Synechocystis sp. PCC 6803 substr. Kazusa
P07652 240 MLDAIGDLFMCGHNIIGAFTAYKSGHALNNKLLQAVLAKQEAWEYVTFQDDAELPLAFKAPS 301 Escherichia coli
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