Conserved Protein Domain Family
ushA

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PRK09558: ushA 
bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic precursor; Reviewed
Links
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Statistics
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PSSM-Id: 236566
Aligned: 152 rows
Threshold Bit Score: 670.837
Created: 9-Dec-2010
Updated: 25-Oct-2021
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
170726304   2 INKLVKGVVATAVLAALAGCNSsddnntpqtaceaagdactKFTVIHTNDNHGRFWQNSKGEY------GMAARKTVIDQ 75 
222099788   1 MRRYLV--LFLVLLLSVFLLGV-------------------RLTILHVNDTHGHAW--TFDEYqnpgigGLAAIATIVEE 57 
157363733   1 MRKFLA--LLLLVIVCFGFATR--------------------LTILHINDTHGHAW--TFSESgnpdigGFAAIATIVEE 56 
148270053   1 MRKFLV--ILLALLITALLLGA-------------------RLTILHVNDTHGHAW--AFDEYrnpgigGLAAIATIVEE 57 
281412066   1 MRKFLV--ILLALLITALLLGA-------------------RLTILHVNDTHGHAW--AFDEYrnpgigGLATIATIVEE 57 
217076477   1 -MRNLKFLVILMVVLALSVFAV-------------------KISIFHVNDTHGHAW--TFSEYhnpdigGFAVIASIIDE 58 
150020031   1 -MKNFKLFVVLFVIFAISLFAT-------------------KVIIFHINDTHGHAW--TFSEYhnpnigGFAVIASIIDE 58 
154249326   1 -MKKFLIVLLLVLLSLFAFAVK--------------------ITVFHINDTHGHAW--SFTDSagniigGFATVASIIDA 57 
160902077   1 MKRFLGILVFVVMVLSVFAGPN-------------------HLVIFHMNDTHGHVWGTEDGG-------GFARAATLINQ 54 
239617293   1 MRKLLL--VSLLVLIAVFVLAE-------------------KITILHINDTHGHAW--TFSEWknpdigGFALIATLVDQ 57 
170726304  76 IRNEVDHAGGETILLSGGDINTGVPESDMQDAVPDFIGMSMLGYDAMAVGNHEFDNPLSTLDMQATIAQFPMLAANIYKK 155
222099788  58 VKREVEEQGGYVIFLHAGDLNTGVPESDLQDAIPDIVGYNMIGLSAMAVGNHEFDNPRDVLLKQMKFADFPFLSANILKE 137
157363733  57 VRKEVESQGGHVLFLHAGDLNTGVPESDQLDAAPDIVALNMMKLDAATFGNHEFDKPKTTLAKQMKLASFPFVCANFADP 136
148270053  58 VKREVESQGGYVIFLHAGDLNTGVPESDLQDAIPDIVGFNMIGLKAMAVGNHEFDNPREVLEKQMKFADFPFLSANIVKE 137
281412066  58 VKREVESQGGYVIFLHAGDLNTGVPESDLQDAIPDIVGFNMMGLKAMAVGNHEFDNPREVLEKQMKFADFPFLSANIVKE 137
217076477  59 ER----AKNPNVLFLHAGDINTGVPESDLLNALPDIFALNRMKLDAMAVGNHEFDKPRDVLKYQMSIAKFPFLSANIYKD 134
150020031  59 ER----AKNPNVLFLHAGDINTGVPESDLLNALPDIFALNRMKLDAMAVGNHEFDKTRDVLMYQMDIAKFPFLSANIYKD 134
154249326  58 ER----SVNPNVIFLHAGDINTGVPESDLMNAIPDIFALNRMRLAAATVGNHEFDKPRDVLMKQISWAKFPFLSANIYKD 133
160902077  55 AREEVAKEGGAVLFLHAGDVNTGIPESDQLDAVPDFLALHYMGLDAMSLGNHEFDKPFEVLEKQYEVAQFPFLGANFVNE 134
239617293  58 FRKE----NPNTLFLHAGDLNTGVPESDLIDAAADIVALNLMGLDAIVLGNHEFDNPPEVLAKQIKWAHFPFLSANIYKD 133
170726304 156 DSngevTSeRYFEPYRVFEINGLKVAIIGFTTVDTPKVVSPDNVASLHFTKPQDEIQTVLAEIEanEKVDMVFALTHMGH 235
222099788 138 N-----GE-PFFTPYILKDFGKLKVAIIGFTTEETTIL-EPLYLEDLKFENALKVAQKIAPELK--NQADVVIALAHL-- 206
157363733 137 EEi------IKQEPYIIKDFENLKVAIFGLTTEETAIL-EPIHLNGATFSNAIETSKKLVPELR--SKADVVIALVHLGW 207
148270053 138 D-----GE-PFFNPYIVEDLGELKIAIIGFTTEETEIL-EPLYLEGLKFENALKVAQKIAPELK--KQADVVIALAHL-- 206
281412066 138 D-----GE-PFFKPYIVEDLGELKIAIIGFTTEETEIL-EPLYLEGLKFENALKVAQKIAPELK--KQADVVIALAHL-- 206
217076477 135 ------GK-PFFTPYIIKNVGGIKVAIFGLTTEETSIL-EPLYSQDLEFRNAIEVAKELVPMLR--EKADVVVALTHLGM 204
150020031 135 ------GK-PFFKPYIIKNVGGVKIAIFGLTTEETAIL-EPLYSRDLEFRNAIEVAKEIVPGLR--KKADIVVALTHLGM 204
154249326 134 ------GK-PLFTPYIIKEVGGVKVAIVGFTTEHTKILEGPNS-EDLEFKNVIEVAKQLIPELK--KQANVVIALTHLGV 203
160902077 135 KR----GG-PVFEPYIIKDYGDFSVGIIGLVTEQTKVL-EPIYLGENTIVDAEETLNMYLPIVQ--EKADVVIVLAHLGY 206
239617293 134 ------GK-PAFTPYIIKEVGGLKVAIVGFTTEETEIL-EALYAQGYEWKSVIEVAKELVPELK--KQADLVIALTHLGT 203
170726304 236 YANGEHGTEA-AGDVKLARSLE-QGQLQAIIGGHSQNPVCMEGDGYAdFKPGDECKPDVQNGTFIMQAHEWGKYVGRADF 313
222099788 207 ----DWGEPK-KENITTTHQLAkVDGIDVVVAGHS-------------HVLGSEVVDEK----IIVSAGEYGKYVGRLDL 264
157363733 208 EPQGEGKTTS----RELAQMVS---GIDVIVDGHSH-------TKFD--------EAQIVNNTIVVQAWEWGKYVGRLDL 265
148270053 207 ----DWGEPK-KEDITTTHQLAgVEGIDVVIAGHS-------------HVLGS----DVVDGKIIASAGEYGKYVGRLDL 264
281412066 207 ----DWGEPK-KEDITTTHQLAgVEGIDVVIAGHS-------------HVLGS----DVVEGKIIASAGEYGKYVGRLDL 264
217076477 205 GQEYEGNYTT-SEELAQN-----VDGIDVIIDGHSHTKLEEAK---------------VINNTIVVQAWEWGKIVGKLDL 263
150020031 205 GQAYEGNYTT-SEELAKM-----VDGIDIIIDGHSHTKLEKAK---------------VINNTIVVQAWEWGKIVGKLEL 263
154249326 204 ---GQGYSELyTTADQLAKEVE---GIDLIIDGHSH-------TQMT--------QPMVVNGVPIVQAFEWAKVLGRADI 262
160902077 207 HADGGRPNLS-VEFTTSDELAEnVSGVDIIIDGHSH-------TLLE--------TPVVINNVIVAQAGDNAENIGRIDL 270
239617293 204 -GKPIVGVNS----IELAEQVD---GIDVIVDGHSHSLLT---------------EPMVVNETLIIQAGEWGKYLGKLDL 260
170726304 314 EYMDGELKLASYKLIPINLKE---KNENDEL--VFITEEIEQDQLVIDALQHYQDLGQELLDVVISSTDGKLEGDRAVVR 388
222099788 265 DIEDGKIVAWHWQAIPVNLKA----YRDGKYeyV--GKPYLENRYVAKALEYFRKVGNEKLDTVIGETKIFLDGEREHVR 338
157363733 266 EIQDGKIVSWNWRPIPVNLKIykgKDDSGKDiyEYAEKPYTENFYVRTVLSYFKSLGSEKLDAVIGETKIILDGERTNVR 345
148270053 265 DIEDGKIVAWHWEAIPVNLKV------YENEkyRYLGKPYLENRYVAKALEYFKKVGNEKLDTVIGETKIYLDGEREHVR 338
281412066 265 DIEDGKIVAWHWEAIPVNLKV------YENEkyRYLGKPYLENRYVAKALEYFKKVGNEKLDTVIGETKIYLDGEREHVR 338
217076477 264 DVENGKIKEWNWTPIPVNLKVykgKDENGNSiyEYVGKPYEPAMYVKVPLDYFAKLGSKKLDTVIGETKVLLDGERAHVR 343
150020031 264 DVENGKIENWNWTPIPVNLKVykgKDEDGNSiyEFVGKEYKPTEYVKVPLDYFAKIGSEKLDTIIGETKILLDGERAHVR 343
154249326 263 EVENGKVVKIDWQAIPVIQSKv-vG--KDESgkNIYQVVTKEALYVKTPLDYFKKLGGAKLDTVIGTTEILLDGERANVR 339
160902077 271 WIDDGRIVDWRGEVIPL-------------------TSDIPEDPFIKMFTDAFYQLGSEALNEVVGVTKVYLDGERAHVR 331
239617293 261 EVENGGIVFVSYESIPIKKAN------------------IESNRAVDIVLDYFKKLGDEKLDTVVGETKILLEGTRAIIR 322
170726304 389 TEQTNLGQLLTRAYGDWVtaNfeptVDFGVMNSGGIRDSIAPGTVSYRDVLTVQPFSNDVSFVTMSGKEVQDYLANVALK 468
222099788 339 SRNTNLTNLITDAMRWKV--K----ADIALTNGEGIRASIKPGKITVRDILTVLPFGNTLYVLELTGEQIMKVLEYSATI 412
157363733 346 ARDTNLSNLICDAMAWKT--R----ADVALTNGGGIRASIKSGKITIRDVLTVLPFGNTLYVIKMTGKEIMEVLNYAATI 419
148270053 339 SKSTNLANLIVDAMRWKV--G----ADIAFTNGGGIRASIKPGKITVRDILTVLPFGNTLYVLELTGEQIMKVLEYAATI 412
281412066 339 SKSTNLANLIVDAMRWKV--G----ADIAFTNGGGIRASIKPGKITVRDILTVLPFGNTLYVLELTGEQIMKVLEYAATI 412
217076477 344 SGDTNLGHLITDAMLWKT--G----ADIAFQNGGGIRASIEPGKITIRNILTVLPFGNTVYVMKMKGSDVMKVLEYAANI 417
150020031 344 SGDTNLGHIITDAMLWKT--G----ADIAFQNGGGIRASVEPGKITIRNILTVLPFGNTVYVMKMTGEQVMKVLEYAATI 417
154249326 340 SKTTNLANLIADSMIWKT--G----ADVALTNGGGIRASIKQGNITIRDVLTVLPFGNTLYVLEMKGSDLIKVFEYAATV 413
160902077 332 SDETNLSNLIADGMIWKT--G----ADVALMNGGGIRASIEAGEITYRDILTVLPFGNTLYVLELTGKDIMDVLNYAATI 405
239617293 323 NQDTNLGHLVADAMVWKT--G----ADLAITNAGGIRASIQPGPITYRDILKVLPFGNTLYIIKITGEQLMEVLKYTTTI 396
170726304 469 TG--GGMAQLYPLEMNVSCdAVEVNpdatsadivqiTSLGGRAFDMAGNYTFSLINFSAKGGDDYPKITEHvn-yvDTQR 545
222099788 413 PEgkGAFLQVSGLTWKSKD-GKVVE-----------VLVNGEPLDPKKTYRVVTNNYMAGGGDGYTMLKEWgg--yDTGF 478
157363733 420 KEgqGAFLHTSGLTWKSVA-GKVVE-----------AKINNEPIIPEKIYTVVTNNYMAQGGDGYTMLKDLpg--yDTGF 485
148270053 413 PEgkGAFLQVSGLTWKSKD-GKVVE-----------VLVNGEPLDPEKKYKVVTNNYMAGGGDGYVMFKEWdg--yDTGY 478
281412066 413 PEgkGAFLQVSGLTWKSKD-GKVVE-----------VLVNGEPLDPEKKYKVVTNNYMAGGGDGYVMFKEWdg--yDTGY 478
217076477 418 PEgkGAFLHVAGLTFESKN-GKVTK-----------VMVNGKPLEMDKVYKVVTNNYMAGGGDGYSMLKEAkatgyDTGF 485
150020031 418 PEgkGAWLHVGGLVWKSEG-GKVTE-----------VMVNGKPLEMDKVYTIVTNNYMAGGGDGYSVLSENkasgyDTGF 485
154249326 414 PNgqGAFLQVAGATWKSES-GKLTE-----------VLVGGKPIDPEKVYKVVTNDYMAAGGDGYSMLKGQkg--yNTFY 479
160902077 406 PDgqGAKLHVAGLTAEIKG-GKATN-----------VKINGKPIDLNKTYKVVTNNYVAAGGDGYTMLAGKpg--yDTYF 471
239617293 397 PAgkGARPQVANLSYKIEN-GEVKD-----------VMIKGEPIDLSKTYTLVTNNYMAAGGDGYKMLKGLeg--yDTGF 462
170726304 546 SDASVLREYFEKNPNIKVADYDPaqGGHPVFyR 578
222099788 479 LMSDAVIEYIQNVLNGVIEEYDN--SQRYVR-E 508
157363733 486 RMDSIVVEYIQTALNGLIEDYDS--NPRYIR-E 515
148270053 479 LMSDAVIEYIQNVLNGKIEEYDD--SQRYVR-E 508
281412066 479 LMSDAVIEYIQNVLNGKIEEYDD--SQRYVR-E 508
217076477 486 VLADVVVEYIQKGLGGKIDSYDDtpRYIRIN-E 517
150020031 486 VLADVVVEYIQKALKGMIENYDD--TPRYIR-K 515
154249326 480 VMADVVVEYIQKALGGKITSYDD--KPRVER-K 509
160902077 472 RDADSLREYIAHLGTIE--DYTS--QERLIElD 500
239617293 463 VLADVVMEYISEISPITEYDDAP--RVIKVEaE 493
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