Conserved Protein Domain Family
H4

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cl23735: H4 Superfamily (this model, PSSM-Id:419976 is obsolete)
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Histone H4, one of the four histones, along with H2A, H2B and H3, which forms the eukaryotic nucleosome core; along with H3, it plays a central role in nucleosome formation; histones bind to DNA and wrap the genetic material into "beads on a string" in which DNA (the string) is wrapped around small blobs of histones (the beads) at regular intervals; play a role in the inheritance of specialized chromosome structures and the control of gene activity; defects in the establishment of proper chromosome structure by histones may activate or silence genes aberrantly and thus lead to disease; the sequence of histone H4 has remained almost invariant in more than 2 billion years of evolution
Statistics
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Accession: cl23735
PSSM Id: 419976
Name: H4
Created: 2-Feb-2016
Updated: 24-Nov-2020
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