XP_003671069 220 YIGILA----------RKTLRSDLENELLKEHIIVLEEFKPIVRRIKRFSSSVENISKISEQLIDRANETSNHGttDSVF 289 
XP_393779     31 ALKELStfftentlnsRRNLRSKIERRSLAINEEFLSAFREVKSSLDGIYQDVLAMNNAVQCMTNRLQTTKTQT--SQLI 108 
XP_001599436  37 ALKELStffkentvedRRNLRSKIERRSLAINEEFIDAFKEVKSVLDNMHRDVAGMNDCVQSMTNRLQTTKART--LQLI 114 
2_pfamImport   1 ALKELNsyfhentiqsRRNLRSNIEKRSLSINENFLSAFRKVKERLDAIYEDVIEMNFAVQSMSQQLVATKAQT--NQLI 78  
XP_970899     33 ALKQLStfytentlqaRRNLRSQIEKRSLDINENFLASFREVKLCFDAVYNDVSEMSKSIQEMTHRLHNAKMQT--KQLL 110 
XP_001967686  35 ALSGLStfftentiqnRRNLRSQIEHRSVGINENFLKAFREVKLSLDAVCDDLDKMATSVETMKSDLETSKALT--KDLI 112 
EDS35193      39 ALTDLSqfytentlqsRRNLRSQIERRSLAINENFLAAFREVKLALDDICGDIDAVSDSVDSMKNLLSSTEAQQ--KELI 116 
Q7QJN1        34 ALSDLStffkentlqsRRNLRSQIEKRSLEINQNFLSAFKEVKEALDGICDDINSMSQSVDSMKSQLRNTEAQT--KDLI 111  Anopheles gamb...
XP_002409735  40 ALKSLSefftennirtRRNLRGDLEKRSLAINEQFLQSFGDVKASLDALCTDMSAMSTACQGMMARLQATRSQT--DTLM 117 
EDV29609      43 ALNALSgffvrndlrsRRNLRSDIEKRSLAINEQFVDAFGKVYTSFNTLRSEIEAMNESCNQMTERLMAAKSET--SDLI 120 

XP_003671069 290 NQVEALQNQVNLLRLKHQLLTNIQKNFTLTQIEDDIIINGP------IDLEFFKVINKVLKIKKNATFLLALDNMEPGTN 363 
XP_393779    109 DQTAKLQNKSQTLSMQQEVANAFIKNFQLTSSEQNILHGSTre--spITEEFFSVVNRVQEIHSSCRILMQSGYQTLGLD 186 
XP_001599436 115 DQTTKLQNESKKLTMQQEIANAFIKRFQLNADELAVLHGSSre--apITEEFFIVINRVQEIHSSCRILMQSGHQTLALD 192 
2_pfamImport  79 EQTTKLQAENEKLTLEEKIASAMINTFQLTESEVTSLREGD------INEEFFRVLERAATIHNDCRSLMQSGHQVIAIE 152 
XP_970899    111 EQTKSLQESGEKNDMQQQIVHAFLETFQLTPDELVALHGNKqkrdapLTNDIFSALDHIQKIHSDCKVLMQSGHQTLALD 190 
XP_001967686 113 DQTNTMQQERDRLEVHQQIAQAFLARFQLSGAEHQLLYGAAkd--apIVADFFKVLDRVQSIHADCRLLMQCGYQTAALD 190 
EDS35193     117 QQANTLQEDNNKLLLQQRIATGFLSRFQLSVTEHQTLYGATrd--epITGEFFNVLDHVQLIHADCRTLLQSGYQTAALD 194 
Q7QJN1       112 LQANTLQEENAKLQIQQKIASGFLSRFQLSVAEHQMLYGAKrd--apITAEFFQVLDRVQRIHTDCRTLMQSGYQTVALD 189  Anopheles gamb...
XP_002409735 118 SRSAALRAQAQRLDERQKLAGAFLHAFQLTPDELQALRTGSp-----GDDRFFDALSRAGRIHADCKLLLRTSQAAAGIQ 192 
EDV29609     121 TKTSKLHNEKQQLQMRARLANLFLEKFQLSPSEIKILHGSRnd---pIKEEFFDALDRVKQIHNDCKLLLRTSQQTAGLK 197 

XP_003671069 364 LINQINSIIQIINKKIFNFL---IDFVYDtshINngtnnnnndnnnnnnnnsysnvNDNVIIFQKSLIFLSNDLPYFDEF 440 
XP_393779    187 IMQRMTLLQEAALERLYRWTqnqCKHIEN---------------------------ERLAPLLIKAMNKLQDRPVLFKYV 239 
XP_001599436 193 IMQRMTLLQEAGLERLYRWTqtqCRHIEN---------------------------EQLVPLLTKAMSKLQERPVLFKYI 245 
2_pfamImport 153 IMEQMAV--------LYRWAqtnCKSIES---------------------------PTISNLLTKAMAKMQDRPVLFKYV 197 
XP_970899    191 IMEQMTLHQEGALERLYRWTqhhCRNVDN---------------------------PDLTEIITQAMARLQERQMLFKYI 243 
XP_001967686 191 IMEEMTLHQEGALERLYRWTqnhCRSLEN---------------------------NEIGPLIVEAMSRLQDRPVLFKYV 243 
EDS35193     195 IMEEMTLHQEAALERLYRWTqshCRNVDA---------------------------NEIGMLVIQGMARLQERPVLFKYV 247 
Q7QJN1       190 IMEEMTLHQEAALERLYRWTqshCRNVES---------------------------NEMGVLIVEAMARLQERPVLFKYV 242  Anopheles gamb...
XP_002409735 193 LMEAMAAHRETAYERLYRWLqaqWRASGA---------------------------DEAAP-LARALTSLRERPVLWGYA 244 
EDV29609     198 IMESMALSQEAAFERLYRWTqseCRMLTG---DT----------------------TEVSSMLTKAMEALQDRPVLFKYS 252 

XP_003671069 441 FKRVTSIRSKIILDEFLSQFeLAhhhssssshknnsktnssdlnkplilsahDPIRYIGDVLASIHSIIANEADFIKSLF 520 
XP_393779    240 LDEYCTARRTVLVGSFIDAL-TLgeiygstp-------------npiemhanDPKRYIGDMLAWLHQVIPVEKENILTLV 305 
XP_001599436 246 LDEYCTSRRSVLVSSFIDAL-TLgrghgsds-------------nsiemhahDPKRYVGDILAWLHQAIPVEKENLLTLL 311 
2_pfamImport 198 ISAYCTHRRSVLVRIFVDAL-TKggpggtpr--------------piemsahDPQRYISDMLAFLHQTVPCERENLAVLL 262 
XP_970899    244 IDEYCIARRSVLVGEFINAL-TRggpsgnpa--------------pielrahDPQIYITDMLVWLNKAIPLEKQNLHLLV 308 
XP_001967686 244 IDEYAIARRAVLVRQFIEAL-TEggpggnpk--------------pielhahDPKRYIGDMFAWLHQSIPTEKENLSLLF 308 
EDS35193     248 IDEYSTARRSVVVRSFIDAL-TVgsssakp----------------iemlahDPKRYIGDMFAYIHQILPVEKENLLMLV 310 
Q7QJN1       243 VDEYSTARRSVVVRSFIDAL-TIggpggnpr--------------piemlahDPKRYIGDMFAYIHQILPPEKENLQMLV 307  Anopheles gamb...
XP_002409735 245 LDELANARRACVVRRFIDALgpme------------------------arsrDPLRYVADMLTWVHECAVGERQLLGQLL 300 
EDV29609     253 LDEVSSARRTAIVRGFIDAL-TRggpggtpr--------------piemhshDPQRYIGDMLAWLHQGVASEKELLQSLL 317 

XP_003671069 521 kfkqilqqeeaqedahndsisylqdknlefltgldlkLLNEIIQSLSNSIKLRIEQII-KFESNPITNFEILQLLKLYQM 599 
XP_393779    306 kgcdktd-----------------------lsdqikqSLSNITDGLCHPLKSRIENVI-SVDIPAALLYSITTLLRFYHM 361 
XP_001599436 312 kacdksd-----------------------mseqitqALSNITEGLCHPLKSRIEHIV-AVEAPSTVLYSVTTLIRFYRA 367 
2_pfamImport 263 sacqtid-----------------------vgeeiqeALATISEGVVTPLKVRIEQIIfSPEIQLKTLYIITNLLSFYRE 319 
XP_970899    309 klcdktd-----------------------lnqqlneALASICEGVCQPLKIRIEKIL-TSSVAPSILYAVTNLIRYYKK 364 
XP_001967686 309 kkcdkqd-----------------------isdqlqsALGYIADGVCHPLKVRVETIL-QAEKDTIVLFTISNLLRFYQQ 364 
EDS35193     311 kmcdkdi------------------------teqiqlAMTTISDGVCHPLKVRVETIL-NSENDTIVLYSISNLMRFYQN 365 
Q7QJN1       308 rncdked-----------------------iseqiqsAMINLSDGVCHPLRVRVETIL-NAEKDTIILYSIFNLIKFYQN 363  Anopheles gamb...
XP_002409735 301 gdaag----------------------------dadaLLGRITQGLCGPLRLRVEQVA-VGPAGPLMLHRLRELLRFYRD 351 
EDV29609     318 kkvlatd-----------------------taalvkeVLTHVTEGVCRPLKVRIEQVL-MSEPGPKVMFKLNNIIKFYCS 373 

XP_003671069 600 MFIKKgIK---SnsSLINNLIILQNLSNDKIINSFTQFIDNVK--------------Esnqfalttaattgtntttttht 662 
XP_393779    362 IIQQV-Ipd-sT---LDSTLTDLLTLSEKSFLNRLQKETRIALgera-------eppG---------------------- 407 
XP_001599436 368 TLKPV-Ihd-sV---LDVMFGDLLELSEKSFVSRLQRETRMALgera-------eppG---------------------- 413 
2_pfamImport 320 TFAQE-VGeksG---LTRGLADCETNSCDTLLEKLGVIVRKEImerv-------slpP---------------------- 366 
XP_970899    365 CICKI-Vtg-gL---LETTLVEVQERSEGAFLTTLQQQVNNILvrv--------eapP---------------------- 409 
XP_001967686 365 IMRQV-Vqg-gS---LEECLVELQKSSEQIYLGALAAQVRSVLqrpsggsglaleppQ---------------------- 417 
EDS35193     366 IINNV-Vkg-gQ---LEQCMVELQAHSETSYLRSLTYQVKQLLtgpnehk-lgleppS---------------------- 417 
Q7QJN1       364 MINGI-Vkg-gQ---LEQCMADMQLFSETTYLNSLTFQVKQLLqgpnenr-lgleppQ---------------------- 415  Anopheles gamb...
XP_002409735 352 LS----LG------PLAACLADLATLADRMLANSLTCHCGQLLdkg--------elpP---------------------- 391 
EDV29609     374 ILRAT-LTndsP---LVNCLGEMDNLSMKMFYASLNSHSAKLLdkv--------elpP---------------------- 419 

XP_003671069 663 akknisikhNGnfgddLLPPEWLSTYLSKITELFEEIDKRGTPfnddahddddddtiatedshdvinqynmERLIesPIF 742 
XP_393779    408 ---------ND-----LVPAPSVSRLLSLLNEIL-----SVVSiae-----------------------drEKDMlqIVS 445 
XP_001599436 414 ---------TD-----LVPAPSVSRLLSLLNEVL-----SVASiae-----------------------drEKDMlqIVS 451 
2_pfamImport 367 ---------KD-----LSPSPGVDYLLSLLRDLL-----SVARvsn-----------------------yhHEFLnkLVS 404 
XP_970899    410 ---------RD-----LSPTPSINHLLAILRDTL-----STASvse-----------------------grESDMgkIAQ 447 
XP_001967686 418 ---------RD-----LVPPPSVARLLNILKEIL-----SVATmvd-----------------------grQADItkIVS 455 
EDS35193     418 ---------TD-----LVPSLSVGRLLNLLKEIL-----SVASmve-----------------------gsQSDIikIVS 455 
Q7QJN1       416 ---------TD-----LVPSPSVGRLLNLLKEIL-----SVASmva-----------------------gsQTDIvkIVG 453  Anopheles gamb...
XP_002409735 392 ---------GD-----LGAPESLRRLLSLVREMLSCGDGRLAPlp------------------------qrQLDVpaLLQ 433 
EDV29609     420 ---------PN-----LGPTETLIQGLVLLRELLASYDAPVAEle------------------------drQIDLkkILS 461 

XP_003671069 743 DVLMKEIKNTFPLAKKNEsvkislLTVQINCFDLINSRLQPFnhsrMIFSKSKnpnihkilDKINDNLQQFIDTMKELQE 822 
XP_393779    446 CIIDPLLQEVNETASRLPtv--dmAVYLLNCMHQIQSTLALY----EYMDQRL--------ERLQAQSDAQIDTLTSEQA 511 
XP_001599436 452 CIIDPLLQEVNETASRLPtv--dmAVYLLNCMHQIHSTLALY----EYMDQRL--------ERLQAQSDAQIDTLTSEQA 517 
2_pfamImport 405 SVLDPLLEGVNVSASRLTtt--dmAVYLLNCLHLMQTTVTLY----EFIDDRL--------ERLQAQCDAQIDTLTSEQA 470 
XP_970899    448 CIMEPLLRAVNEQASRLPpt--dmAVYMLNCMYSMYTCLSLY----EFMDERL--------ERLQAQSDAQIDTLTSEQA 513 
XP_001967686 456 CVIDPLLQSVQESAAHLPtv--dmGVYLLNCLHHMQSSLAVY----EYMDERV--------ERLQAQSDAQLDTLTSEQA 521 
EDS35193     456 CVIDPLLQSIQESASHLPtt--dmAVYLLNSLYQIESVLTIY----EYMEERL--------ERLQAQSDAQLDTLTSEQA 521 
Q7QJN1       454 CVIDPLLQSVQESASHLPtt--dmAVYLLNSLYQIESVISIY----EYMEERL--------ERLRAQSDAQIDTLTSEQA 519  Anopheles gamb...
XP_002409735 434 QVLEPALEACQLSASRLSaa--dgATYLANCAQLAHSTLAPF----ECTEPWL--------ERLEALAQHQLGLLSQEQQ 499 
EDV29609     462 CIVDPLLQMCTVSAASLSaa--dmACYMINCIYCIHSTLALY----EFTDDHL--------EKLKAQIDAHMDTLVSEQA 527 

XP_003671069 823 KLLFEKTGLSIYNNLFNMIFPIdavqdkldyDMyqSLLDNPLMNIDTINNtVHTKLNEYLPNALNDIQENlLFKLNSPSI 902 
XP_393779    512 SSLVAHLNLGSIYTILQGH-E----------QG--PLSSIPGMDPLSVKE-FTNKLEAFLVMPDVLLLPQ-ISLLQSSNH 576 
XP_001599436 518 SSLVAHLNLGPIYNILQGH-Y----------QG--PLSSIPGMDPLSIKE-FTNKLEGFLVMPDVLLLPQ-ISLLQSSTH 582 
2_pfamImport 471 SSLVANLNLGPIYMILEEQGS----------TG--PLTHIPGMQPSSLAN-FISKFDSFVSMPELLLLPQ-VHCLLSGVH 536 
XP_970899    514 SSLVANLNLGPIYTILQDH-T----------QG--PLSGIPGMEPTNLKN-FLAKLDYLLASPDSVLLPQ-INLLLSSKH 578 
XP_001967686 522 SSLVANLNLGPIYAILQ--------------------SNQSKIETNLLKI-FMSKMDAFLELPDVLLLPQ-VQLIMSSSH 579 
EDS35193     522 SSLVANLNLGPIYTVLQ--------------------SSASQIEQRHLQL-FMSKLDSFLEMPEILLLPQ-VNLLLSGVH 579 
Q7QJN1       520 SSLVANLNLGPIYTVLQ--------------------GNASQIDQRHLQT-FVVKLEQFLQTPEILLVPQ-VNLLLSSGH 577  Anopheles gamb...
XP_002409735 500 AALLSQLGLSTPVRLLGQG----------------PLATLPGCDVLALRT-AGSRLARLLEDGF--PLPL-GQLLASAGH 559 
EDV29609     528 GYILAQSGLGFIYSTLQEQQNN---------KI--PLSSVHGMDAKSVKS-ALVKFDSYLSSHDALLMPH-CALLLSTKI 594 

XP_003671069 903 VDAICDHCFGKISLFYKIFRDVLFHLY--AnedvknaNEKKQKISDI 947 
XP_393779    577 RSIVQKRSFEVIGAIYKQLYESCHDPKnlYqn---anSLFSRTPEDL 620 
XP_001599436 583 RTNTQRRAFEVIGAIYKQLYDACHEPKnlYqn---pgSLFGHTPEEL 626 
2_pfamImport 537 RWTVQRRATEVILAIYKKVYSSVHDPAnlYds---pqTLVPRTPQEV 580 
XP_970899    579 KKAVQKRAFDVLLAIYKQLYEGVHNPDnlYen---pgSILSKTPDEL 622 
XP_001967686 580 RATVQKRSFNVIVAIYKQIYDRVHDPAngFeh---pdKLLHRTPEQV 623 
EDS35193     580 RATVQKRSFNVIVAIYKQIYERIHDPAggFer---peTVLAKTPEQV 623 
Q7QJN1       578 RATVQKRSFNVIIAIYRQIYERINDPKngYtn---peTILSKTPEQV 621  Anopheles gambiae str. PEST
XP_002409735 560 RRILRATTLAALCDVYAQLHAAVHDPAngYpd---psLLLPVPPEEI 603 
EDV29609     595 RERVQKQSVELVCNAYESLYKAVYNPFneYke---psSVIIHTSEQV 638