1T0G,1SOX,1MJ4,1NX7,3KS0


Conserved Protein Domain Family
Cyt-b5
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pfam00173: Cyt-b5 
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Cytochrome b5-like Heme/Steroid binding domain
This family includes heme binding domains from a diverse range of proteins. This family also includes proteins that bind to steroids. The family includes progesterone receptors. Many members of this subfamily are membrane anchored by an N-terminal transmembrane alpha helix. This family also includes a domain in some chitin synthases. There is no known ligand for this domain in the chitin synthases.
Links
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Statistics
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PSSM-Id: 459698
Aligned: 80 rows
Threshold Bit Score: 48.3864
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
1T0G_A         13 TAEQLSQYNgt-------dESK--PIYVAIKGRVFDVTTGK-SFY-------GSGGDYSMFAGKDASRALGKMs---KNE 72   thale cress
Q4X0H6        956 SAAELSSHN----------GKDghSSFIAIRGVVFDLDKFMpGHYph----iVPESALKKYAGVDATGLFPVQvsalCQG 1021 Aspergillus f...
XP_663922     962 SPAELSSHD----------GKDghSSYTSIRGLVLDLGEFMdSHYpg----iVPDSALKKYAGVDSTALFPVQvsalCLG 1027
XP_010763234  808 TEKEVSFHQ----------GDN--DYYVSIHGSVYDISKFW--KTphtfardTSRSAMDPFRGQNLDVYFPVPlnvaCRG 873 
O13395        141 NLSQLSQHA----------GEN--DYYAAVRGTVYDFSKFYkGDHsditnlqTSSDLMLQLAGQDLTGYFPVPlsvgCQS 208  Ustilago mayd...
Q97TF9         67 TLEELSKYN----------GENgkPAYVAVNGTVYDLSlap---------swGGGTHFGLYAGKDLSSEFNSChkgims- 126  Clostridium a...
SZF03430      967 SASELSSHN----------GKSgkPAYIAIRGQVFDLSEFApSHYpn----iIPQKSILAYAGLDATALFPVQvsalCQG 1032
EPB85956       23 TEEKFQELI----------KQG--DSVFIYEQKVYRVNNFM-AKHp------GGEAALRSALGRDVTDEIRTM----HPP 79  
Q9VR91       1292 RRADMENLL----------LDG--SRCIILAGYVCDLSGYN-CESe------TLRSVLDSGLGKDLTAEMSSQvhrtAME 1352 fruit fly
P71799          6 P--DVRERDggprpappagGPRlsDVWV-YNGRAYDLSEWI-SKHp------GGAFFIGRTKNRDITAIVKSYh---RDP 72   Mycobacterium...

1T0G_A         73 EDVspslegltekei--------ntlndwetkfeAKY----------------------PVVGRVV 108  thale cress
Q4X0H6       1022 KSGsvdpmvlldyrptnisgsattisgtdtnsvyHDFrhftndsrpdwfyeqmvmlkanYLKGYVG 1087 Aspergillus fumigatus
XP_663922    1028 KDGnvdpkvlldykptnfsgsvtstssgdpnsvyHDFryfrddyrpdwyaeqmiylranYYKGWIG 1093
XP_010763234  874 LGAseniqiqhnktdailfpnalhtsgtfqtdttLKLrdvnwygg------vflprireYYKGDVV 933 
O13395        209 LVSdtslalmptanntplisqaihtsgplqgdtsSKLhdinwypd------rflpfvkkLRKGYYV 268  Ustilago maydis 521
Q97TF9        127 ------------------------------------------------------iltslPRVGALI 138  Clostridium acetobutylicum
SZF03430     1033 VNGtidssiqldymstntsgsasvisssdtnykyHDFraftndsrpdwffeqmmllranFRRGNIG 1098
EPB85956       80 QVY-------------------------------EKMin-------------------lYCIGDYM 95  
Q9VR91       1353 Hil------------------------------------------------------ehHKLGKYM 1364 fruit fly
P71799         73 AIV-------------------------------ERIlq------------------rrYALGRDA 89   Mycobacterium tuberculosis
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