2LJK,3DEX


Conserved Protein Domain Family
CXXU_selWTH
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TIGR02174: CXXU_selWTH 
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selT/selW/selH selenoprotein domain
This model represents a domain found in both bacteria and animals, including animal proteins SelT, SelW, and SelH, all of which are selenoproteins. In a CXXC motif near the N-terminus of the domain, selenocysteine may replace the second Cys. Proteins with this domain may include an insert of about 70 amino acids. This model is broader than the current SelW model pfam05169 in Pfam.
Links
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Statistics
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PSSM-Id: 274013
Aligned: 19 rows
Threshold Bit Score: 72.7003
Created: 8-Oct-2014
Updated: 25-Oct-2021
Structure
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Program:
Drawing:
Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
2LJK_A              27 IVVEYCEPCGFEATYLELASAVKEQYPGi--EIE--SRLG---------------------------------------- 62  human
AAO86696             5 VHVVYCGGUGYRPKFIKLKTLLEDEFPNe-lEITgeGTPS---------------------------------------- 43  zebrafish
O15532               5 VRVVYCGACGYKSKYLQLKKKLEDEFPGr-lDICgeGTPQ---------------------------------------- 43  human
P59797             265 IRVTYCGLUSYSLRYILLKKSLEQQFPNh-lLFEedRAAQ---------------------------------------- 303 human
AAN32901             6 VHVLYCGGUGYGSRYRSLENAIRMKFPNadiKFSfeATPQ---------------------------------------- 45  Chlamydom...
AAO86697             5 VKIEYCGAUGYEPRFQELKREICGNCPD----AEvsGFVG---------------------------------------- 40  zebrafish
FlyBase:CG15456-PA   4 VEVEYCGICNFSGQCHLLREFLLASSPD----LDisCRTG---------------------------------------- 39  fruit fly
AAH54578             9 LKFQICVSUGYKRVFEEYTQALYQRYPDi--RIEgeNYLPlplyrhiasflsmfkllligviilgkdpfalcgmqapgiw 86  zebrafish
Q9VMV6              44 MTFLYCYSCGYRKAFEDYVGLLGEKYPQi--QVNggNYDPpglnyylskmifalkiiiivsvvsavspftflglntpsww 121 fruit fly
Q19892              72 LTILYCVSCGYKQAFNQFYEFAKEKYPGl--VIEggNFSPdfwkgclaqivgvakigliaivitgsnpfeyigfgypqil 149 Caenorhab...

2LJK_A              63 --------------------------GTGAFEIEINGQLVFSKLENGGFPYEKDLIEAIRR 97  human
AAO86696            44 --------------------------TTGWLEVEVNGKLVHSKKNGDGFVDSDSKMQKIVT 78  zebrafish
O15532              44 --------------------------ATGFFEVMVAGKLIHSKKKGDGYVDTESKFLKLVA 78  human
P59797             304 --------------------------ATGEFEVFVNGRLVHSKKRGDGFVN-ESRLQKIVS 337 human
AAN32901            46 --------------------------ATGFFEVEVNGELVHSKKNGGGHVDNQEKVERIFA 80  Chlamydomonas reinhardtii
AAO86697            41 --------------------------RRGCFEIQINDFLVFSKLESGGFPYSEDIIEAVVK 75  zebrafish
FlyBase:CG15456-PA  40 --------------------------RRGSFEVSIDGQLVHSKLSCLAFPQHASVLAQVQK 74  fruit fly
AAH54578            87 vwsqenkiyacmmvfffsnmienqcmSTGAFEITLNDVPVWSKLESGHLPSMQQLVQILEN 147 zebrafish
Q9VMV6             122 shmqankiyacmmifflgnmleaqliSSGAFEITLNDVPVWSKLQTGRFPSPEVLFQIIDN 182 fruit fly
Q19892             150 qtahynrfsysllvfmignlfestlsSTGAFEIFLGDKQIWSKISKERVPTQEEFLNLIDL 210 Caenorhabditis elegans
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