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C1_ARHGEF18-like: protein kinase C conserved region 1 (C1 domain) found in uncharacterized Rho guanine nucleotide exchange factor 18 (ARHGEF18)-like proteins
The family includes a group of uncharacterized proteins that show high sequence similarity to verteb...
View in Cn3D Specific ProteinProteinSuperfamilySuperfamily MembersPubMed
C1: protein kinase C conserved region 1 (C1 domain) superfamily
The C1 domain is a cysteine-rich zinc binding domain that does not bind DNA nor possess structural s...
View in Cn3D ProteinSuperfamily MembersPubMed
PH-like: Pleckstrin homology-like domain
The PH-like family includes the PH domain, both the Shc-like and IRS-like PTB domains, the ran-bindi...
View in Cn3D
PH_ARHGEF18: Rho guanine nucleotide exchange factor 18 Pleckstrin homology (PH) domain
ARHGEF18, also called p114RhoGEF, is a key regulator of RhoA-Rock2 signaling that is crucial for mai...
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