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Select item 44036681.

StatPearls [Internet].

Treasure Island (FL): StatPearls Publishing; 2025 Jan-.

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Select item 21951622.

StemBook [Internet].

Cambridge (MA): Harvard Stem Cell Institute; 2008-.

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Select item 14152803.

Madame Curie Bioscience Database [Internet].

Austin (TX): Landes Bioscience; 2000-2013.

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Select item 14589844.

GeneReviews® [Internet].

Adam MP, Feldman J, Mirzaa GM, et al., editors.

Seattle (WA): University of Washington, Seattle; 1993-2025.

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Select item 16686905.

Holland-Frei Cancer Medicine. 6th edition.

Kufe DW, Pollock RE, Weichselbaum RR, et al., editors.

Hamilton (ON): BC Decker; 2003.

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Select item 28215246.

PDQ Cancer Information Summaries [Internet].

Bethesda (MD): National Cancer Institute (US); 2002-.

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Select item 34012947.

Endotext [Internet].

Feingold KR, Ahmed SF, Anawalt B, et al., editors.

South Dartmouth (MA): MDText.com, Inc.; 2000-.

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Select item 56852968.

The EBMT Handbook: Hematopoietic Cell Transplantation and Cellular Therapies [Internet]. 8th edition.

Sureda A, Corbacioglu S, Greco R, et al., editors.

Cham (CH): Springer; 2024.

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Select item 26591829.

Database of Abstracts of Reviews of Effects (DARE): Quality-assessed Reviews [Internet].

York (UK): Centre for Reviews and Dissemination (UK); 1995-.

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Select item 150279210.

Molecular Imaging and Contrast Agent Database (MICAD) [Internet].

Bethesda (MD): National Center for Biotechnology Information (US); 2004-2013.

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Select item 136515011.

Dynamics of Cancer: Incidence, Inheritance, and Evolution.

Frank SA.

Princeton (NJ): Princeton University Press; 2007.

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Select item 313182012.

Regenerative Medicine.

National Academy of Sciences (US).

Washington (DC): National Academies Press (US); 2003.

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Select item 320857013.

Scientific and Medical Aspects of Human Reproductive Cloning.

National Academy of Sciences (US), National Academy of Engineering (US), Institute of Medicine (US) and National Research Council (US) Committee on Science, Engineering, and Public Policy.

Washington (DC): National Academies Press (US); 2002.

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Select item 189578814.

Molecular Biology of the Cell. 4th edition.

Alberts B, Johnson A, Lewis J, et al.

New York: Garland Science; 2002.

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Select item 440153015.

Stem Cells in Neuroendocrinology [Internet].

Pfaff D, Christen Y, editors.

Cham (CH): Springer; 2016.

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Select item 479792616.

The European Blood and Marrow Transplantation Textbook for Nurses: Under the Auspices of EBMT [Internet].

Kenyon M, Babic A, editors.

Cham (CH): Springer; 2018.

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Select item 160721217.

Developmental Biology. 6th edition.

Gilbert SF.

Sunderland (MA): Sinauer Associates; 2000.

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Select item 186024218.

WormBook: The Online Review of C. elegans Biology [Internet].

Pasadena (CA): WormBook; 2005-2018.

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Select item 570487619.

Jasper's Basic Mechanisms of the Epilepsies. 5th edition.

Noebels JL, Avoli M, Rogawski MA, et al., editors.

New York: Oxford University Press; 2024.

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Select item 498314220.

Examining the State of the Science of Mammalian Embryo Model Systems: Proceedings of a Workshop.

National Academies of Sciences, Engineering, and Medicine; Health and Medicine Division; Board on Health Sciences Policy; Beachy SH, Nicholson A, Hackmann M, et al., editors.

Washington (DC): National Academies Press (US); 2020 Jun 2.

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Figure 22-36Dependence of hemopoietic stem cells on contact with stromal cells

The cartoon shows a dependence on two signaling mechanisms for which there is some evidence. The real system is certainly more complex; the dependence of hemopoietic cells on contact with stromal cells cannot be absolute, since small numbers of the functional stem cells can be found free in the circulation.

Renewal by Multipotent Stem Cells: Blood Cell Formation.

Alberts B, Johnson A, Lewis J, et al. Molecular Biology of the Cell. 4th edition. New York: Garland Science; 2002.
Figure 4Localization of melanocyte stem cells in the hair follicle.

(A) Schematic illustration of the hair follicle. The hair follicle is divided into two portions: two-thirds of lower hair follicle (transit portion) that completely reforms itself over the hair cycle; and the upper permanent portion of the follicle that is maintained throughout hair cycling. Melanocyte stem cells reside in the lower permanent protion including the bulge region, while differentiated melanocytes are localized in the hair matrix. (B) Whole mount staining of the Dct-LaZ hair follilce. Using Dct-LaZ transgenic mice, melanocyte stem cells can be located at the lower permanet protion of the hair follicle, which is anatomically seggregated from differentiated melanocytes in the hair bulb.

Melanocyte stem cells.

StemBook [Internet]. Cambridge (MA): Harvard Stem Cell Institute; 2008-.
Figure 12.6

Cell lineage hierarchy in a small intestine crypt of a mouse. Active stem cells give rise to daughter stem cells that remain near the base of the crypt and the first generation of the transit lineage pathway (T₁), the potential clonogenic stem cells. The early transit generations retain the ability to return to fully active stem cells, but normally they move either up or down the crypt. If the cells move down, they differentiate into Paneth cells that line the base of the crypt. If the cells move up, they differentiate into goblet cells and then mature enterocytes, after which they die and are shed from the epithelial surface. Redrawn from Marshman et al. (2002).

Stem Cells: Tissue Renewal.

Frank SA. Dynamics of Cancer: Incidence, Inheritance, and Evolution. Princeton (NJ): Princeton University Press; 2007.
Figure 21-32Making a chimeric mouse with ES or teratocarcinoma stem cells

The experiment shows that the stem cells can combine with the cells of a normal blastocyst to form a healthy chimeric mouse.

Cell Diversification in the Early Animal Embryo ,

Alberts B, Bray D, Lewis J, et al. Molecular Biology of the Cell. 3rd edition. New York: Garland Science; 1994.