"Prions" - Books

Result Filters

Results: 1 to 20 of 112 books (372 items)

<< First< Prev

Page of 6

Select item 31879641.

Advancing Prion Science: Guidance for the National Prion Research Program: Interim Report.

Institute of Medicine (US) Committee on Transmissible Spongiform Encephalopathies: Assessment of Relevant Science; Erdtmann R, Sivitz L, editors.

Washington (DC): National Academies Press (US); 2003.

Top results in this book Table of Contents

Select item 44036682.

StatPearls [Internet].

Treasure Island (FL): StatPearls Publishing; 2026 Jan-.

Top results in this book Table of Contents

Select item 49442883.

Interventions to reduce the risk of surgically transmitted Creutzfeldt–Jakob disease: a cost-effective modelling review.

Stevenson M, Uttley L, Oakley JE, et al.

Southampton (UK): NIHR Journals Library; 2020 Feb. (Health Technology Assessment, No. 24.11.)

Top results in this book Table of Contents

Select item 31898344.

Self-Perpetuating Structural States in Biology, Disease, and Genetics.

National Academy of Sciences (US); Lindquist S, Henikoff S, editors.

Washington (DC): National Academies Press (US); 2002.

Top results in this book Table of Contents

Select item 14152805.

Madame Curie Bioscience Database [Internet].

Austin (TX): Landes Bioscience; 2000-2013.

Top results in this book Table of Contents

Select item 25504546.

Addressing Foodborne Threats to Health: Policies, Practices, and Global Coordination: Workshop Summary.

Institute of Medicine (US) Forum on Microbial Threats.

Washington (DC): National Academies Press (US); 2006.

Top results in this book Table of Contents

Select item 14589847.

GeneReviews® [Internet].

Adam MP, Bick S, Mirzaa GM, et al., editors.

Seattle (WA): University of Washington, Seattle; 1993-2026.

Top results in this book Table of Contents

Select item 18813828.

Basic Neurochemistry: Molecular, Cellular and Medical Aspects. 6th edition.

Siegel GJ, Agranoff BW, Albers RW, et al., editors.

Philadelphia: Lippincott-Raven; 1999.

Top results in this book Table of Contents

Select item 18957889.

Molecular Biology of the Cell. 4th edition.

Alberts B, Johnson A, Lewis J, et al.

New York: Garland Science; 2002.

Top results in this book Table of Contents

Select item 158168610.

Medical Microbiology. 4th edition.

Baron S, editor.

Galveston (TX): University of Texas Medical Branch at Galveston; 1996.

Top results in this book Table of Contents

Select item 305758011.

Neurodegeneration: Exploring Commonalities Across Diseases: Workshop Summary.

Forum on Neuroscience and Nervous System Disorders; Board on Health Sciences Policy; Institute of Medicine.

Washington (DC): National Academies Press (US); 2013 Dec 12.

Top results in this book Table of Contents

Select item 505411612.

Microbial Triggers of Chronic Human Illness: This report is based on a colloquium, sponsored by the American Academy of Microbiology, held June 25-27, 2004, in New Orleans, Louisiana.

Washington (DC): American Society for Microbiology; 2005.

Top results in this book Table of Contents

Select item 318262813.

Microbial Threats to Health: Emergence, Detection, and Response.

Institute of Medicine (US) Committee on Emerging Microbial Threats to Health in the 21st Century; Smolinski MS, Hamburg MA, Lederberg J, editors.

Washington (DC): National Academies Press (US); 2003.

Top results in this book Table of Contents

Select item 233066814.

Microbial Evolution and Co-Adaptation: A Tribute to the Life and Scientific Legacies of Joshua Lederberg: Workshop Summary.

Institute of Medicine (US) Forum on Microbial Threats.

Washington (DC): National Academies Press (US); 2009.

Top results in this book Table of Contents

Select item 454479415.

Management of Animal Care and Use Programs in Research, Education, and Testing. 2nd edition.

Weichbrod RH, Thompson GAH, Norton JN, editors.

Boca Raton (FL): CRC Press/Taylor & Francis; 2018.

Top results in this book Table of Contents

Select item 297609416.

Improving Food Safety Through a One Health Approach: Workshop Summary.

Institute of Medicine (US).

Washington (DC): National Academies Press (US); 2012.

Top results in this book Table of Contents

Select item 233288617.

Infectious Disease Movement in a Borderless World: Workshop Summary.

Institute of Medicine (US) Forum on Microbial Threats.

Washington (DC): National Academies Press (US); 2010.

Top results in this book Table of Contents

Select item 306289018.

Guidelines for the Clinical Management of Thalassaemia [Internet]. 2nd Revised edition.

Cappellini MD, Cohen A, Eleftheriou A, et al.

Nicosia (CY): Thalassaemia International Federation; 2008.

Top results in this book Table of Contents

Select item 557058419.

Nutrient Requirements of Dairy Cattle: Eighth Revised Edition.

National Academies of Sciences, Engineering, and Medicine; Division on Earth and Life Studies; Board on Agriculture and Natural Resources; Committee on Nutrient Requirements of Dairy Cattle.

Washington (DC): National Academies Press (US); 2021 Aug 30.

Top results in this book Table of Contents

Select item 255392420.

Neuroproteomics.

Alzate O, editor.

Boca Raton (FL): CRC Press/Taylor & Francis; 2010.

Top results in this book Table of Contents

<< First< Prev

Page of 6

Next >Last >>

Supplemental Content

Images search in Bookshelf

Fig. 2.

Possible routes of propagation of ingested prions. After oral uptake, prions may penetrate the intestinal mucosa through M cells and reach Peyer's patches as well as the enteric nervous system. Depending on the host, prions may replicate and accumulate in spleen and lymph nodes. Myeloid dendritic cells are thought to mediate transport within the lymphoreticular system. From the lymphoreticular system and likely from other sites, prions proceed along the peripheral nervous system to finally reach the brain, either directly via the vagus nerve or via the spinal cord, under involvement of the sympathetic nervous system.

Transmission of prions.

National Academy of Sciences (US); Lindquist S, Henikoff S, editors. Self-Perpetuating Structural States in Biology, Disease, and Genetics. Washington (DC): National Academies Press (US); 2002.
Fig. 3.

Transmission of mouse scrapie prions by stainless steel wire. Stainless steel wires were inserted into the brains of scrapie-infected mice for 5, 30, or 120 min, washed exhaustively, and introduced permanently into brains of indicator mice. Five minutes of contact sufficed for the wire to acquire a maximum load of infectivity, equivalent to the injection of 30 µl of 1% homogenate of the same brain. Data from ref. 73.

Transmission of prions.

National Academy of Sciences (US); Lindquist S, Henikoff S, editors. Self-Perpetuating Structural States in Biology, Disease, and Genetics. Washington (DC): National Academies Press (US); 2002.
FIGURE 6

The prevalence of CJD prions within central nervous tissue.

Cost-effectiveness.

Stevenson M, Uttley L, Oakley JE, et al. Interventions to reduce the risk of surgically transmitted Creutzfeldt–Jakob disease: a cost-effective modelling review. Southampton (UK): NIHR Journals Library; 2020 Feb.
Fig. 4.

Infection of mouse neuroblastoma cells by plastic-bound prions. Wells of a polystyrene 96-well microtiter plate were exposed to various dilutions of a homogenate of scrapie-prion-infected mouse brain, washed exhaustively, and dried. Ten thousand N2a/Bos2 mouse neuroblastoma cells (77) were cultured in the wells for 3 days, then transferred to 24-well plates and cultured 4 wk, splitting 1:10 twice a week. The cells were then transferred to coverslips and assayed for the presence of PrP^Sc(78). Optimal infectivity resulted when plates were coated with 0.0125% homogenate. High concentrations of brain proteins bound to the plastic appear inhibitory for cell infection (P.-C.K. and C.W., unpublished results).

Transmission of prions.

National Academy of Sciences (US); Lindquist S, Henikoff S, editors. Self-Perpetuating Structural States in Biology, Disease, and Genetics. Washington (DC): National Academies Press (US); 2002.