Key Questions What is the comparative effectiveness of different mammography-based breast cancer screening strategies (e.g., by modality, interval, initiation age, use of supplemental imaging, or personalization based on risk factors) on breast cancer morbidity and breast cancer–specific or all-cause mortality? Does comparative effectiveness differ by population characteristics and risk markers (e.g., age, breast density, race and ethnicity, family history)?What is the comparative effectiveness of different mammography-based breast cancer screening strategies (e.g., by modality, interval, initiation age, use of supplemental imaging, or personalization based on risk factors) on the incidence and progression to advanced breast cancer? Does comparative effectiveness differ by population characteristics and risk markers (e.g., age, breast density, race and ethnicity, family history)?What are the comparative harms of different breast mammography-based cancer screening strategies (e.g., by modality, interval, initiation age, use of supplemental imaging, or personalization based on risk factors)? Do the comparative harms vary by population characteristics and risk markers (e.g., age, breast density, race and ethnicity, family history)?
Henderson JT, Webber EM, Weyrich M, et al. Screening for Breast Cancer: A Comparative Effectiveness Review for the U.S. Preventive Services Task Force [Internet]. Rockville (MD): Agency for Healthcare Research and Quality (US); 2024 Apr.