"Nuclear Reprogramming" - Books

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Select item 21951621.

StemBook [Internet].

Cambridge (MA): Harvard Stem Cell Institute; 2008-.

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Select item 52412082.

The Heterogeneity of Cancer Metabolism [Internet]. 2nd edition.

Le A, editor.

Cham (CH): Springer; 2021.

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Select item 14152803.

Madame Curie Bioscience Database [Internet].

Austin (TX): Landes Bioscience; 2000-2013.

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Select item 34012944.

Endotext [Internet].

Feingold KR, Ahmed SF, Anawalt B, et al., editors.

South Dartmouth (MA): MDText.com, Inc.; 2000-.

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Select item 32085705.

Scientific and Medical Aspects of Human Reproductive Cloning.

National Academy of Sciences (US), National Academy of Engineering (US), Institute of Medicine (US) and National Research Council (US) Committee on Science, Engineering, and Public Policy.

Washington (DC): National Academies Press (US); 2002.

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Select item 31318206.

Regenerative Medicine.

National Academy of Sciences (US).

Washington (DC): National Academies Press (US); 2003.

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Select item 45423767.

Innovative Medicine: Basic Research and Development [Internet].

Nakao K, Minato N, Uemoto S, editors.

Tokyo: Springer; 2015.

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Select item 31466408.

Animal Biotechnology: Science-Based Concerns.

National Research Council (US) Committee on Defining Science-Based Concerns Associated with Products of Animal Biotechnology.

Washington (DC): National Academies Press (US); 2002.

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Select item 55080389.

RNA, the Epicenter of Genetic Information: A new understanding of molecular biology.

Mattick J, Amaral P.

Abingdon (UK): CRC Press; 2022 Sep 20.

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Select item 538535010.

Introduction to Epigenetics [Internet].

Paro R, Grossniklaus U, Santoro R, et al.

Cham (CH): Springer; 2021.

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Select item 438852411.

Exploring the State of the Science in the Field of Regenerative Medicine: Challenges of and Opportunities for Cellular Therapies: Proceedings of a Workshop.

National Academies of Sciences, Engineering, and Medicine; Health and Medicine Division; Board on Health Sciences Policy; Forum on Regenerative Medicine.

Washington (DC): National Academies Press (US); 2017 Mar 15.

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Select item 307920412.

The Art and Politics of Science.

Varmus H.

New York: W.W. Norton & Company; 2009.

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Select item 287874813.

The Science and Applications of Synthetic and Systems Biology: Workshop Summary.

Institute of Medicine (US) Forum on Microbial Threats.

Washington (DC): National Academies Press (US); 2011.

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Select item 440153014.

Stem Cells in Neuroendocrinology [Internet].

Pfaff D, Christen Y, editors.

Cham (CH): Springer; 2016.

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Select item 454429015.

Etiology and Morphogenesis of Congenital Heart Disease: From Gene Function and Cellular Interaction to Morphology [Internet].

Nakanishi T, Markwald RR, Baldwin HS, et al., editors.

Tokyo: Springer; 2016.

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Select item 469147016.

Gulf War and Health: Volume 11: Generational Health Effects of Serving in the Gulf War.

National Academies of Sciences, Engineering, and Medicine; Health and Medicine Division; Board on Population Health and Public Health Practice; Committee on Gulf War and Health, Volume 11: Generational Health Effects of Serving in the Gulf War.

Washington (DC): National Academies Press (US); 2018 Nov 28.

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Select item 236397417.

Human Herpesviruses: Biology, Therapy, and Immunoprophylaxis.

Arvin A, Campadelli-Fiume G, Mocarski E, et al., editors.

Cambridge: Cambridge University Press; 2007.

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Select item 518920818.

Translational Neuroscience: Toward New Therapies [Internet].

Nikolich K, Hyman SE, editors.

Cambridge (MA): MIT Press; 2015.

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Select item 186024219.

WormBook: The Online Review of C. elegans Biology [Internet].

Pasadena (CA): WormBook; 2005-2018.

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Select item 487112820.

Hepatocellular Carcinoma [Internet].

Tirnitz-Parker JEE, editor.

Brisbane (AU): Codon Publications; 2019 Oct 24.

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Supplemental Content

Images search in Bookshelf

Fig. 1.

Diagrams to show the time scale of nuclear reprogramming in Xenopus and the mouse. (A) Oogenesis and early development of Xenopus. (B) In Xenopus egg nuclear transfers, reprogrammed gene expression is seen at the late blastula stage after at least 12 cell division cycles. (C) In Xenopus oocyte nuclear transfers, reprogrammed gene expression is seen in the complete absence of DNA replication and cell division. (D) In mouse nuclear transfer to eggs, reprogrammed gene expression has been seen at the blastocyst stage.

Nuclear reprogramming and stem cell creation.

National Academy of Sciences (US). Regenerative Medicine. Washington (DC): National Academies Press (US); 2003.
Figure 2Methods of nuclear reprogramming, their advantages and limitations.

Four techniques for restoring developmental potential to a somatic nucleus have been described in the literature. In nuclear transfer, the genetic material of an oocyte or zygote is replaced with that of a differentiated cell such as a fibroblast. Following development to the blastocyst stage, pluripotent ntES cells can be derived as from fertilized embryos. In cellular fusion, hybridization between ES cells and somatic cells yields tetraploid ES cell lines. In direct reprogramming, the retroviral-mediated introduction of a small number of transcription factors is sufficient to confer a pluripotent phenotype. Finally, explantation of testes tissue from neonatal and adult mice into appropriate culture conditions has been shown to result in the production of multipotent adult spermatagonial (MAS) cells.

Inducing pluripotency.

StemBook [Internet]. Cambridge (MA): Harvard Stem Cell Institute; 2008-.