"Molecular Mimicry" - Books

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Select item 30760201.

Adverse Effects of Vaccines: Evidence and Causality.

Committee to Review Adverse Effects of Vaccines; Institute of Medicine; Stratton K, Ford A, Rusch E, et al., editors.

Washington (DC): National Academies Press (US); 2011 Aug 25.

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Select item 44036682.

StatPearls [Internet].

Treasure Island (FL): StatPearls Publishing; 2026 Jan-.

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Select item 14152803.

Madame Curie Bioscience Database [Internet].

Austin (TX): Landes Bioscience; 2000-2013.

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Select item 44650644.

Autoimmunity: From Bench to Bedside [Internet].

Anaya JM, Shoenfeld Y, Rojas-Villarraga A, et al., editors.

Bogota (Colombia): El Rosario University Press; 2013 Jul 18.

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Select item 53216725.

Essentials of Glycobiology [Internet]. 4th edition.

Varki A, Cummings RD, Esko JD, et al., editors.

Cold Spring Harbor (NY): Cold Spring Harbor Laboratory Press; 2022.

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Select item 14416186.

Helicobacter pylori: Physiology and Genetics.

Mobley HLT, Mendz GL, Hazell SL, editors.

Washington (DC): ASM Press; 2001.

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Select item 54017687.

Streptococcus pyogenes: Basic Biology to Clinical Manifestations [Internet]. 2nd edition.

Ferretti JJ, Stevens DL, Fischetti VA, editors.

Oklahoma City (OK): University of Oklahoma Health Sciences Center; 2022 Oct 8.

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Select item 34012948.

Endotext [Internet].

Feingold KR, Adler RA, Ahmed SF, et al., editors.

South Dartmouth (MA): MDText.com, Inc.; 2000-.

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Select item 23639749.

Human Herpesviruses: Biology, Therapy, and Immunoprophylaxis.

Arvin A, Campadelli-Fiume G, Mocarski E, et al., editors.

Cambridge: Cambridge University Press; 2007.

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Select item 567095210.

Evidence Review of the Adverse Effects of COVID-19 Vaccination and Intramuscular Vaccine Administration.

National Academies of Sciences, Engineering, and Medicine; Health and Medicine Division; Board on Population Health and Public Health Practice; Committee to Review Relevant Literature Regarding Adverse Events Associated with Vaccines; Rosenberg D, Kumova OK, Stratton K, et al., editors.

Washington (DC): National Academies Press (US); 2024 Aug 16.

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Select item 420372011.

Streptococcus pyogenes : Basic Biology to Clinical Manifestations [Internet].

Ferretti JJ, Stevens DL, Fischetti VA, editors.

Oklahoma City (OK): University of Oklahoma Health Sciences Center; 2016-.

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Select item 328789212.

Adverse Events Associated with Childhood Vaccines: Evidence Bearing on Causality.

Institute of Medicine (US) Vaccine Safety Committee; Stratton KR, Howe CJ, Johnston RB Jr, editors.

Washington (DC): National Academies Press (US); 1994.

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Select item 319128013.

Immunization Safety Review: Influenza Vaccines and Neurological Complications.

Institute of Medicine (US) Immunization Safety Review Committee; Stratton K, Alamario DA, Wizemann T, et al., editors.

Washington (DC): National Academies Press (US); 2004.

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Select item 319702414.

Immunization Safety Review: Multiple Immunizations and Immune Dysfunction.

Institute of Medicine (US) Immunization Safety Review Committee; Stratton K, Wilson CB, McCormick MC, editors.

Washington (DC): National Academies Press (US); 2002.

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Select item 140373815.

Polymicrobial Diseases.

Brogden KA, Guthmiller JM, editors.

Washington (DC): ASM Press; 2002.

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Select item 320725216.

Multiple Sclerosis: Current Status and Strategies for the Future.

Institute of Medicine (US) Committee on Multiple Sclerosis: Current Status and Strategies for the Future; Joy JE, Johnston RB Jr, editors.

Washington (DC): National Academies Press (US); 2001.

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Select item 145898417.

GeneReviews® [Internet].

Adam MP, Bick S, Mirzaa GM, et al., editors.

Seattle (WA): University of Washington, Seattle; 1993-2026.

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Select item 166869018.

Holland-Frei Cancer Medicine. 6th edition.

Kufe DW, Pollock RE, Weichselbaum RR, et al., editors.

Hamilton (ON): BC Decker; 2003.

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Select item 531965619.

NEUROLOGY OF COVID–19 [Internet].

Priori A, editor.

Milano: Milano University Press; 2021 Feb.

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Select item 165410620.

Immunobiology: The Immune System in Health and Disease. 5th edition.

Janeway CA Jr, Travers P, Walport M, et al.

New York: Garland Science; 2001.

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Figure 4Molecular mimicry and anti-β2-GPI:

Production of antibodies against β2-GPI by the presence of the tetanus toxoid. As a consequence of the recognition and destruction of the bacteria, there is presentation of bacterial peptides. The peptide that is shared by the toxoid and the β2-GPI may be among them. As a result, there is production of antibodies that recognize both molecules. Adapted from Cervera et al. (57).

Infection and autoimmune diseases.

Anaya JM, Shoenfeld Y, Rojas-Villarraga A, et al., editors. Autoimmunity: From Bench to Bedside [Internet]. Bogota (Colombia): El Rosario University Press; 2013 Jul 18.
Figure 3

Molecular mimicry between H. pylori LPS and gastric H⁺,K⁺-ATPase. Mouse or human gastric H⁺,K⁺-ATPase (in concentrations of 2 to 10 μg per lane) were subjected to SDS-PAGE and immunoblotted with monoclonal antibodies specific for Le^x (below), Le^y (middle), and peptide epitopes of the β-chain (upper panel), respectively. Due to heterogeneity in glycosylation, the β-chain appears as a smear.

Lipopolysaccharide Lewis Antigens.

Mobley HLT, Mendz GL, Hazell SL, editors. Helicobacter pylori: Physiology and Genetics. Washington (DC): ASM Press; 2001.
Figure 14.

Following group A Streptococcus (GAS) adhesion to and invasion of the pharyngeal epithelium, GAS antigens activate both B and T cells. Molecular mimicry between GAS group A carbohydrate or serotype-specific M protein and the host heart, brain or joint tissues can lead to an autoimmune response, which causes the major manifestations of acute rheumatic fever (ARF). BCR, B cell receptor; TCR, T cell receptor (Carapetis, et al., 2016; Stollerman, 1997).

Post-Streptococcal Autoimmune Sequelae, Rheumatic Fever and Beyond: A New Perspective.

Ferretti JJ, Stevens DL, Fischetti VA, editors. Streptococcus pyogenes: Basic Biology to Clinical Manifestations [Internet]. 2nd edition. Oklahoma City (OK): University of Oklahoma Health Sciences Center; 2022 Oct 8.
Figure 13.41Virus infection can break tolerance to a transgenic viral protein expressed in pancreatic β cells

Mice made transgenic for the lymphocytic choriomeningitis virus (LCMV) nucleoprotein under the control of the rat insulin promoter express the nucleoprotein in their pancreatic β cells, but do not respond to this protein and therefore do not develop an autoimmune diabetes. However, if the transgenic mice are infected with LCMV, a potent antiviral cytotoxic T-cell response is elicited, and this kills the β cells, leading to diabetes. It is thought that infectious agents can sometimes elicit T-cell responses that cross-react with self peptides (a process known as molecular mimicry) and that this could cause autoimmune disease in a similar way.

Self-tolerance and its loss.

Janeway CA Jr, Travers P, Walport M, et al. Immunobiology: The Immune System in Health and Disease. 5th edition. New York: Garland Science; 2001.