"Macrophage Activation" - Books

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Select item 14152801.

Madame Curie Bioscience Database [Internet].

Austin (TX): Landes Bioscience; 2000-2013.

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Select item 44036682.

StatPearls [Internet].

Treasure Island (FL): StatPearls Publishing; 2026 Jan-.

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Select item 34012943.

Endotext [Internet].

Feingold KR, Adler RA, Ahmed SF, et al., editors.

South Dartmouth (MA): MDText.com, Inc.; 2000-.

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Select item 44650644.

Autoimmunity: From Bench to Bedside [Internet].

Anaya JM, Shoenfeld Y, Rojas-Villarraga A, et al., editors.

Bogota (Colombia): El Rosario University Press; 2013 Jul 18.

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Select item 16541065.

Immunobiology: The Immune System in Health and Disease. 5th edition.

Janeway CA Jr, Travers P, Walport M, et al.

New York: Garland Science; 2001.

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Select item 16686906.

Holland-Frei Cancer Medicine. 6th edition.

Kufe DW, Pollock RE, Weichselbaum RR, et al., editors.

Hamilton (ON): BC Decker; 2003.

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Select item 23639747.

Human Herpesviruses: Biology, Therapy, and Immunoprophylaxis.

Arvin A, Campadelli-Fiume G, Mocarski E, et al., editors.

Cambridge: Cambridge University Press; 2007.

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Select item 15027928.

Molecular Imaging and Contrast Agent Database (MICAD) [Internet].

Bethesda (MD): National Center for Biotechnology Information (US); 2004-2013.

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Select item 43693809.

Canakinumab (Ilaris) [Internet].

Ottawa (ON): Canadian Agency for Drugs and Technologies in Health; 2016 Nov.

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Select item 536791010.

Prevention and Treatment of Atherosclerosis: Improving State-of-the-Art Management and Search for Novel Targets [Internet].

von Eckardstein A, Binder CJ, editors.

Cham (CH): Springer; 2022.

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Select item 145898411.

GeneReviews® [Internet].

Adam MP, Bick S, Mirzaa GM, et al., editors.

Seattle (WA): University of Washington, Seattle; 1993-2026.

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Select item 140373812.

Polymicrobial Diseases.

Brogden KA, Guthmiller JM, editors.

Washington (DC): ASM Press; 2002.

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Select item 466662213.

Mechanisms of Vascular Disease: A Reference Book for Vascular Specialists [Internet].

Fitridge R, Thompson M, editors.

Adelaide (AU): University of Adelaide Press; 2011.

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Select item 553046814.

Cardiovascular Signaling in Health and Disease [Internet].

Parinandi NL, Hund TJ, editors.

Cham (CH): Springer; 2022.

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Select item 454237615.

Innovative Medicine: Basic Research and Development [Internet].

Nakao K, Minato N, Uemoto S, editors.

Tokyo: Springer; 2015.

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Select item 429943216.

Polycystic Kidney Disease [Internet].

Li X, editor.

Brisbane (AU): Codon Publications; 2015 Nov.

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Select item 526503617.

Cerebral Ischemia [Internet].

Pluta R, editor.

Brisbane (AU): Exon Publications; 2021 Nov 6.

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Select item 323143418.

Military Strategies for Sustainment of Nutrition and Immune Function in the Field.

Institute of Medicine (US) Committee on Military Nutrition Research.

Washington (DC): National Academies Press (US); 1999.

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Select item 410317419.

Brain Neurotrauma: Molecular, Neuropsychological, and Rehabilitation Aspects.

Kobeissy FH, editor.

Boca Raton (FL): CRC Press/Taylor & Francis; 2015.

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Select item 290889220.

Herbal Medicine: Biomolecular and Clinical Aspects. 2nd edition.

Benzie IFF, Wachtel-Galor S, editors.

Boca Raton (FL): CRC Press/Taylor & Francis; 2011.

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Supplemental Content

Images search in Bookshelf

Fig. 24.4

New Classification Criteria for Diagnosis of Macrophage Activation Syndrome

Pediatric Rheumatology.

Almoallim H, Cheikh M, editors. Skills in Rheumatology [Internet]. Singapore: Springer; 2021.
Figure 8.43Granulomas form when an intracellular pathogen or its constituents cannot be totally eliminated

When mycobacteria (red) resist the effects of macrophage activation, a characteristic localized inflammatory response called a granuloma develops. This consists of a central core of infected macrophages. The core may include multinucleated giant cells, which are fused macro-phages, surrounded by large macro-phages often called epithelioid cells. Mycobacteria can persist in the cells of the granuloma. The central core is surrounded by T cells, many of which are CD4-positive. The exact mechanisms by which this balance is achieved, and how it breaks down, are unknown. Granulomas, as seen in the bottom panel, also form in the lungs and elsewhere in a disease known as sarcoidosis, which may be caused by occult mycobacterial infection. Photograph courtesy of J. Orrell.

Macrophage activation by armed CD4 TH1 cells.

Janeway CA Jr, Travers P, Walport M, et al. Immunobiology: The Immune System in Health and Disease. 5th edition. New York: Garland Science; 2001.
Fig. 13.5

Algorithmic approach for hyperferritinemia with pancytopenia in rheumatological diseases patients. This approach is based on ferritin level; the authors suggest to broaden the differential diagnosis and to rule out disease activity and non-rheumatological causes, including systemic diseases, infections, and drug-induced and primary hematological diseases. The evidence to support this approach is based on cumulative literature, current guidelines, and the author’s experience. (Abbreviations: R/O rule out, MAS macrophage activation syndrome, HLH hemophagocyticlymphohistiocytosis)

The Blood in Rheumatology.

Almoallim H, Cheikh M, editors. Skills in Rheumatology [Internet]. Singapore: Springer; 2021.
Figure 11.15Defects in phagocytic cells are associated with persistence of bacterial infection

Defects in the leukocyte integrins with a common β₂ subunit (CD18) or defects in the selectin ligand, sialyl-Lewis^x, prevent phagocytic cell adhesion and migration to sites of infection (leukocyte adhesion deficiency). The respiratory burst is defective in chronic granulomatous disease, glucose-6-phosphate dehydrogenase (G6PD) deficiency, and myeloperoxidase deficiency. In chronic granulomatous disease, infections persist because macrophage activation is defective, leading to chronic stimulation of CD4 T cells and hence to granulomas. Vesicle fusion in phagocytes is defective in Chediak-Higashi syndrome. These diseases illustrate the critical role of phagocytes in removing and killing pathogenic bacteria.

Inherited immunodeficiency diseases.

Janeway CA Jr, Travers P, Walport M, et al. Immunobiology: The Immune System in Health and Disease. 5th edition. New York: Garland Science; 2001.