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Select item 23580521.

Probe Reports from the NIH Molecular Libraries Program [Internet].

Bethesda (MD): National Center for Biotechnology Information (US); 2010-.

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Select item 29026902.

Assay Guidance Manual [Internet].

Markossian S, Grossman A, Baskir H, et al., editors.

Bethesda (MD): Eli Lilly & Company and the National Center for Advancing Translational Sciences; 2004-.

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Select item 52032483.

SARS-CoV-2 Assays [Internet].

Bethesda (MD): National Center for Advancing Translational Sciences (NCATS); 2020-.

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Select item 23306684.

Microbial Evolution and Co-Adaptation: A Tribute to the Life and Scientific Legacies of Joshua Lederberg: Workshop Summary.

Institute of Medicine (US) Forum on Microbial Threats.

Washington (DC): National Academies Press (US); 2009.

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Select item 28787485.

The Science and Applications of Synthetic and Systems Biology: Workshop Summary.

Institute of Medicine (US) Forum on Microbial Threats.

Washington (DC): National Academies Press (US); 2011.

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Select item 44036686.

StatPearls [Internet].

Treasure Island (FL): StatPearls Publishing; 2026 Jan-.

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Select item 56644007.

The effects and safety of testosterone replacement therapy for men with hypogonadism: the TestES evidence synthesis and economic evaluation.

Cruickshank M, Hudson J, Hernández R, et al.

Southampton (UK): National Institute for Health and Care Research; 2024 Aug. (Health Technology Assessment, No. 28.43.)

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Select item 55396708.

Toxicological Profile for Polycyclic Aromatic Hydrocarbons.

Atlanta (GA): Agency for Toxic Substances and Disease Registry (US); 1995 Aug.

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Select item 29953989.

The Social Biology of Microbial Communities: Workshop Summary.

Institute of Medicine (US) Forum on Microbial Threats.

Washington (DC): National Academies Press (US); 2012.

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Select item 446506410.

Autoimmunity: From Bench to Bedside [Internet].

Anaya JM, Shoenfeld Y, Rojas-Villarraga A, et al., editors.

Bogota (Colombia): El Rosario University Press; 2013 Jul 18.

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Select item 518831211.

Trace Metals and Infectious Diseases [Internet].

Nriagu JO, Skaar EP, editors.

Cambridge (MA): MIT Press; 2015.

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Select item 552713612.

Occupational Exposure as a Firefighter.

IARC Working Group on the Identification of Carcinogenic Hazards to Humans.

Lyon (FR): International Agency for Research on Cancer; 2023. (IARC Monographs on the Identification of Carcinogenic Hazards to Humans, No. 132.)

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Select item 563221613.

National Cancer Institute’s Nanotechnology Characterization Laboratory Assay Cascade Protocols [Internet].

Bethesda (MD): National Cancer Institute (US); 2005 May 1-.

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Select item 462671414.

Calcium Entry Channels in Non-Excitable Cells.

Kozak JA, Putney JW Jr, editors.

Boca Raton (FL): CRC Press/Taylor & Francis; 2018.

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Select item 265918215.

Database of Abstracts of Reviews of Effects (DARE): Quality-assessed Reviews [Internet].

York (UK): Centre for Reviews and Dissemination (UK); 1995-.

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Select item 407267616.

Bitumens and Bitumen Emissions, and Some N- and S-Heterocyclic Polycyclic Aromatic Hydrocarbons.

IARC Working Group on the Evaluation of Carcinogenic Risks to Humans.

Lyon (FR): World Health Organization; 2013.

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Select item 141528017.

Madame Curie Bioscience Database [Internet].

Austin (TX): Landes Bioscience; 2000-2013.

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Select item 150279218.

Molecular Imaging and Contrast Agent Database (MICAD) [Internet].

Bethesda (MD): National Center for Biotechnology Information (US); 2004-2013.

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Select item 292265219.

EOS 2D/3D X-ray Imaging System: A Systematic Review and Economic Evaluation.

McKenna C, Wade R, Faria R, et al.

Southampton (UK): NIHR Journals Library; 2012 Mar. (Health Technology Assessment, No. 16.14.)

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Select item 413492220.

Some Traditional Herbal Medicines, Some Mycotoxins, Naphthalene and Styrene.

IARC Working Group on the Evaluation of Carcinogenic Risks to Humans.

Lyon (FR): International Agency for Research on Cancer; 2002. (IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, No. 82.)

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Supplemental Content

Images search in Bookshelf

Figure 7.15Vignetting artifact, i. e., luminescence drops at image periphery

X-ray Imaging.

Maier A, Steidl S, Christlein V, et al., editors. Medical Imaging Systems: An Introductory Guide [Internet]. Cham (CH): Springer; 2018.
Figure 8:

Simplified Luminescence Detection

Basics of Assay Equipment and Instrumentation for High Throughput Screening.

Markossian S, Grossman A, Baskir H, et al., editors. Assay Guidance Manual [Internet]. Bethesda (MD): Eli Lilly & Company and the National Center for Advancing Translational Sciences; 2004-.
Figure 19:

iCell cardiomyocytes (Cellular Dynamics, Inc.) were plated and grown in medium containing RealTime-Glo™ reagents (pro-substrate and NanoLuc luciferase) in a 37°C/5% CO₂ humidified incubator. At various time points, the luminescence signal was monitored on a Tecan M1000Pro plate reader. After 2 days, digitonin was added to a final concentration of 200 µg/ml. The luminescence was read continually, starting immediately after digitonin addition.

Cell Viability Assays.

Markossian S, Grossman A, Baskir H, et al., editors. Assay Guidance Manual [Internet]. Bethesda (MD): Eli Lilly & Company and the National Center for Advancing Translational Sciences; 2004-.
Figure 21:

THP1 cells were grown in medium containing the RealTime-Glo™ Assay Reagent and treated with 1μM doxorubicin. Luminescence was recorded every 4 hours to monitor changes in cell viability. At selected times, Caspase-Glo^® 3/7 Assay Reagent supplemented with a specific inhibitor for the shrimp luciferase was added to parallel wells. The plates were incubated at room temperature for 1 hour, then luminescence recorded from the firefly-derived luciferase in the caspase detection reagent.

Cell Viability Assays.

Markossian S, Grossman A, Baskir H, et al., editors. Assay Guidance Manual [Internet]. Bethesda (MD): Eli Lilly & Company and the National Center for Advancing Translational Sciences; 2004-.