"Lactones" - Books

Result Filters

Results: 1 to 20 of 81 books (843 items)

<< First< Prev

Page of 5

Select item 33059301.

Eplerenone (Inspra) (25 mg Tablet and 50 mg Tablet): As an Adjunct to Standard Therapy to Reduce the Risk of Cardiovascular Mortality and Hospitalization for Heart Failure in Patients With NYHA Class II Systolic Chronic Heart Failure and Left Ventricular Systolic Dysfunction [Internet].

Ottawa (ON): Canadian Agency for Drugs and Technologies in Health; 2014 Oct.

Top results in this book Table of Contents

Select item 42459542.

Calcineurin Inhibitors for Renal Transplant [Internet].

Leas BF, Uhl S, Sawinski DL, et al.

Rockville (MD): Agency for Healthcare Research and Quality (US); 2016 Mar. (Comparative Effectiveness Reviews, No. 166.)

Top results in this book Table of Contents

Select item 42086703.

Guidelines for Stopping Mass Drug Administration and Verifying Elimination of Human Onchocerciasis: Criteria and Procedures.

Geneva: World Health Organization; 2016.

Top results in this book Table of Contents

Select item 46109344.

Everolimus (Afinitor) [Internet].

Ottawa (ON): Canadian Agency for Drugs and Technologies in Health; 2017 Sep.

Top results in this book Table of Contents

Select item 49812285.

NIEHS Technical Report on the Reproductive, Developmental, and General Toxicity Studies of 3′-Azido-3′-deoxythymidine (AZT) and Clarithromycin Combinations (CAS Nos. 30516-87-1 and 81103-11-9) Administered by Gavage to Swiss CD-1® Mice [Internet].

Rao GN, Giles HD, Rogers TS, et al.

Research Triangle Park (NC): National Institute of Environmental Health Sciences; 2003 Oct. (Toxicity Report, No. 9.)

Top results in this book Table of Contents

Select item 50585086.

WHO Guideline on Mass Drug Administration of Azithromycin to Children under Five Years of Age to Promote Child Survival [Internet].

Geneva: World Health Organization; 2020.

Top results in this book Table of Contents

Select item 47235107.

Ocular Prophylaxis for Gonococcal Ophthalmia Neonatorum: A Reaffirmation Evidence Update for the U.S. Preventive Services Task Force [Internet].

Guirguis-Blake JM, Evans CV, Rushkin M.

Rockville (MD): Agency for Healthcare Research and Quality (US); 2019 Jan. (Evidence Synthesis, No. 173.)

Top results in this book Table of Contents

Select item 26591828.

Database of Abstracts of Reviews of Effects (DARE): Quality-assessed Reviews [Internet].

York (UK): Centre for Reviews and Dissemination (UK); 1995-.

Top results in this book Table of Contents

Select item 48163589.

Ivermectin for Parasitic Skin Infections of Scabies: A Review of Comparative Clinical Effectiveness, Cost-Effectiveness, and Guidelines [Internet].

Chiu S, Argaez C.

Ottawa (ON): Canadian Agency for Drugs and Technologies in Health; 2019 May 16.

Top results in this book Table of Contents

Select item 461280610.

Management and Treatment of Cervicitis: A Review of Clinical Effectiveness and Guidelines [Internet].

Young C, Argáez C.

Ottawa (ON): Canadian Agency for Drugs and Technologies in Health; 2017 Sep 21.

Top results in this book Table of Contents

Select item 483090811.

Ivermectin for Parasitic Skin Infections of Lice: A Review of Comparative Clinical Effectiveness, Cost-Effectiveness, and Guidelines [Internet].

Young C, Argáez C.

Ottawa (ON): Canadian Agency for Drugs and Technologies in Health; 2019 May 14.

Top results in this book Table of Contents

Select item 456572812.

Drugs and Lactation Database (LactMed®) [Internet].

Bethesda (MD): National Institute of Child Health and Human Development; 2006-.

Top results in this book Table of Contents

Select item 422694213.

Some Drugs and Herbal Products.

IARC Working Group on the Evaluation of Carcinogenic Risks to Humans.

Lyon (FR): International Agency for Research on Cancer; 2016. (IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, No. 108.)

Top results in this book Table of Contents

Select item 454874614.

Coffee, Tea, Mate, Methylxanthines and Methylglyoxal.

IARC Working Group on the Evaluation of Carcinogenic Risks to Humans.

Lyon (FR): International Agency for Research on Cancer; 1991. (IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, No. 51.)

Top results in this book Table of Contents

Select item 299539815.

The Social Biology of Microbial Communities: Workshop Summary.

Institute of Medicine (US) Forum on Microbial Threats.

Washington (DC): National Academies Press (US); 2012.

Top results in this book Table of Contents

Select item 546242616.

Toxicological Profile for Endosulfan.

Atlanta (GA): Agency for Toxic Substances and Disease Registry (US); 2015 Aug.

Top results in this book Table of Contents

Select item 485381617.

LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet].

Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases; 2012-.

Top results in this book Table of Contents

Select item 432481018.

Household Use of Solid Fuels and High-temperature Frying.

IARC Working Group on the Evaluation of Carcinogenic Risks to Humans.

Lyon (FR): International Agency for Research on Cancer; 2010. (IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, No. 95.)

Top results in this book Table of Contents

Select item 455368619.

Some Industrial Chemicals.

IARC Working Group on the Evaluation of Carcinogenic Risks to Humans.

Lyon (FR): International Agency for Research on Cancer; 1994. (IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, No. 60.)

Top results in this book Table of Contents

Select item 287874820.

The Science and Applications of Synthetic and Systems Biology: Workshop Summary.

Institute of Medicine (US) Forum on Microbial Threats.

Washington (DC): National Academies Press (US); 2011.

Top results in this book Table of Contents

<< First< Prev

Page of 5

Next >Last >>

Supplemental Content

Images search in Bookshelf

Figure 15.2

Diversity in the sialic acids. The 9-carbon backbone common to all known sialic acids is shown. Natural substitutions that have been described to date (at R₄, R₅, R₇, R₈, and R₉) are indicated. Additional diversity can be generated by occurrence of lactones (from R₁ to hydroxyl groups on other saccharides), by dehydro forms (eliminating R₂), by the internal anhydro forms indicated, as well as by various types of glycosidic linkages (via R₃, to the underlying sugar chain). (Reprinted, with permission, from [13] Varki 1997.)

Sialic Acids.

Varki A, Cummings R, Esko J, et al., editors. Essentials of Glycobiology. Cold Spring Harbor (NY): Cold Spring Harbor Laboratory Press; 1999.
FIGURE A19-4AHL inter-kingdom signalling

In bacteria, acyl homoserine lactones (AHLs) cross the cell membrane and interact with cytoplasmic receptors of the LuxR family. Binding the AHL to the LuxR-type receptor allows proper folding of this protein, which allows the receptor to dimerize and bind to its target sequence on DNA to regulate gene expression. In the absence of signal, LuxR-type proteins misfold and are targeted for degradation. In mammalian cells, AHLs also gain access to the cytoplasm by crossing the plasma membrane. The identity of the mammalian receptor (or receptors) for AHLs in mammalian cells is unknown. However, if there are intracellular receptors, it is proposed that the interaction with the AHL ligand activates these receptors and thereby allows their transportation into the nucleus, where they could control gene expression.

Contributed Manuscripts.

Institute of Medicine (US) Forum on Microbial Threats. The Social Biology of Microbial Communities: Workshop Summary. Washington (DC): National Academies Press (US); 2012.
FIGURE 14.2

Diversity in the sialic acids. The nine-carbon backbone common to all known Sias is shown, in the α configuration. The following variations can occur at the carbon positions indicated:
R1 = H (on dissociation at physiological pH, gives the negative charge of Sia); can form lactones with hydroxyl groups on the same molecule or on other glycans; can form lactams with a free amino group at C-5; tauryl group.
R2 = H; alpha linkage to Gal(3/4/6), GalNAc(6), GlcNAc(4/6), Sia (8/9), or 5-O-Neu5Gc; oxygen linked to C-7 in 2,7-anhydro molecule; anomeric hydroxyl eliminated in Neu2en5Ac (double bond to C-3).
R4 = H; -acetyl; anhydro to C-8; Fuc; Gal.
R5 = Amino; N-acetyl; N-glycolyl; hydroxyl; N-acetimidoyl; N-glycolyl-O-acetyl; N-glycolyl-O-methyl; N-glycolyl-O-2-Neu5Gc.
R7 = H; -acetyl; anhydro to C-2; substituted by amino and N-acetyl in Leg.
R8 = H; -acetyl; anhydro to C-4; -methyl; -sulfate; Sia; Glc.
R9 = -H; -acetyl; -lactyl; -phosphate; -sulfate; Sia; OH substituted by H in Leg.

Sialic Acids.

Varki A, Cummings RD, Esko JD, et al., editors. Essentials of Glycobiology. 2nd edition. Cold Spring Harbor (NY): Cold Spring Harbor Laboratory Press; 2009.