"Janus Kinases" - Books

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See janB (JANUS) janus B in the Gene database

janus in Drosophila melanogaster (2)Drosophila simulans All 6 Gene records

Results: 1 to 20 of 85 books (245 items)

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Select item 44036681.

StatPearls [Internet].

Treasure Island (FL): StatPearls Publishing; 2026 Jan-.

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Select item 48538162.

LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet].

Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases; 2012-.

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Select item 14152803.

Madame Curie Bioscience Database [Internet].

Austin (TX): Landes Bioscience; 2000-2013.

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Select item 45657284.

Drugs and Lactation Database (LactMed®) [Internet].

Bethesda (MD): National Institute of Child Health and Human Development; 2006-.

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Select item 34012945.

Endotext [Internet].

Feingold KR, Adler RA, Ahmed SF, et al., editors.

South Dartmouth (MA): MDText.com, Inc.; 2000-.

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Select item 16541066.

Immunobiology: The Immune System in Health and Disease. 5th edition.

Janeway CA Jr, Travers P, Walport M, et al.

New York: Garland Science; 2001.

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Select item 48022467.

Nicotinic Acetylcholine Receptor Signaling in Neuroprotection [Internet].

Akaike A, Shimohama S, Misu Y, editors.

Singapore: Springer; 2018.

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Select item 18957888.

Molecular Biology of the Cell. 4th edition.

Alberts B, Johnson A, Lewis J, et al.

New York: Garland Science; 2002.

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Select item 53935569.

Leukemia [Internet].

Li W, editor.

Brisbane (AU): Exon Publications; 2022 Oct 16.

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Select item 429943210.

Polycystic Kidney Disease [Internet].

Li X, editor.

Brisbane (AU): Codon Publications; 2015 Nov.

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Select item 265918211.

Database of Abstracts of Reviews of Effects (DARE): Quality-assessed Reviews [Internet].

York (UK): Centre for Reviews and Dissemination (UK); 1995-.

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Select item 588356012.

Delgocitinib (Anzupgo): Therapeutic area: Chronic hand eczema: Reimbursement Review [Internet].

Ottawa (ON): Canadian Agency for Drugs and Technologies in Health; 2026 Mar.

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Select item 553901413.

Deucravacitinib (Sotyktu): CADTH Reimbursement Review: Therapeutic area: Psoriasis, moderate to severe plaque [Internet].

Ottawa (ON): Canadian Agency for Drugs and Technologies in Health; 2023 Oct.

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Select item 236397414.

Human Herpesviruses: Biology, Therapy, and Immunoprophylaxis.

Arvin A, Campadelli-Fiume G, Mocarski E, et al., editors.

Cambridge: Cambridge University Press; 2007.

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Select item 584709415.

Tofacitinib: Therapeutic area: Juvenile idiopathic arthritis, idiopathic arthritis: Reimbursement Review [Internet].

Ottawa (ON): Canadian Agency for Drugs and Technologies in Health; 2025 Nov.

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Select item 446506416.

Autoimmunity: From Bench to Bedside [Internet].

Anaya JM, Shoenfeld Y, Rojas-Villarraga A, et al., editors.

Bogota (Colombia): El Rosario University Press; 2013 Jul 18.

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Select item 235805217.

Probe Reports from the NIH Molecular Libraries Program [Internet].

Bethesda (MD): National Center for Biotechnology Information (US); 2010-.

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Select item 159952418.

The Cell: A Molecular Approach. 2nd edition.

Cooper GM.

Sunderland (MA): Sinauer Associates; 2000.

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Select item 572645419.

Etrasimod (Velsipity): Therapeutic area: Ulcerative colitis: Reimbursement Review [Internet].

Ottawa (ON): Canadian Agency for Drugs and Technologies in Health; 2024 Dec.

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Select item 553046820.

Cardiovascular Signaling in Health and Disease [Internet].

Parinandi NL, Hund TJ, editors.

Cham (CH): Springer; 2022.

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FIGURE 4Converging signaling pathways

NOTE: AdiopR = adiponectin receptor; AMPK = 5′ adenosine monophosphate-activated protein kinase; IGF = insulin-like growth factor; IL = interleukin; IRS = insulin receptor substrate, JAK = Janus kinases; mTOR = mammalian target of rapamycin; P = phosphorylated; PI3K = phosphoinositide 3-kinase; STAT = signal transducer and activator of transcription; TSC = tuberous sclerosis protein.
SOURCE: Hursting presentation (October 31, 2011). Reprinted with permission from Stephen Hursting.

Workshop Summary.

National Cancer Policy Forum; Board on Health Care Services; Institute of Medicine. The Role of Obesity in Cancer Survival and Recurrence: Workshop Summary. Washington (DC): National Academies Press (US); 2012 Apr 3.
Figure 6.22Many cytokine receptors signal by a rapid pathway using receptor-associated kinases to activate specific transcription factors

Many cytokines act via receptors that are associated with cytoplasmic Janus kinases (JAKs). The receptor consists of at least two chains, each associated with a specific JAK (left panel). Ligand binding and dimerization of the receptor chains brings together the JAKs, which can transactivate each other, subsequently phosphorylating tyrosines in the receptor tails (second panel). Members of the STAT (signal transducer and activators of transcription) family of proteins bind to the phosphorylated receptors and are themselves phosphorylated by the JAKs (third panel). On phosphorylation, STAT proteins dimerize by binding phosphotyrosine residues in SH2 pockets and go rapidly to the nucleus, where they bind to and activate transcription of a variety of genes important for adaptive immunity.

Other signaling pathways that contribute to lymphocyte behavior.

Janeway CA Jr, Travers P, Walport M, et al. Immunobiology: The Immune System in Health and Disease. 5th edition. New York: Garland Science; 2001.