E. faecalis genome plot. The outermost ring shows E. faecalis V583 chromosomal (scaffold 4) and plasmid scaffolds (scaffold 1, pTEF2; scaffold 2, pTEF3; scaffold 3, pTEF1), with each V583 gene represented as a radial position along the ring. The locations of V583 variable regions are shown (98): A, integrated plasmid; B, prophage 1; C, PAI; D, prophage 2; E, prophage 3; F, putative island efaB5; G, prophage 4; H, prophage 5; I, putative island; J, vancomycin resistance (vanB) transposon; K, integrated plasmid; L, prophage 6; M, prophage 7. Seventeen additional E. faecalis genomes are represented by the rings below V583. Genes are colored by phylogenetic distance from V583 (from dark to light green with increasing phylogenetic distance). Strains shown, from outermost to innermost rings, are V583, T11, OG1RF, Merz96, T8, T2, D6, X98, T3, T1, Fly1, CH188, HIP11704, ATCC4200, E1Sol, AR01/DG, DS5, and JH1. Patterns suggestive of recombination (darker colored genes indicate close phylogenetic relatedness to V583) occur in Merz96, T2, and JH1, which flank genomic islands.
Gilmore MS, Clewell DB, Ike Y, et al., editors. Enterococci: From Commensals to Leading Causes of Drug Resistant Infection [Internet]. Boston: Massachusetts Eye and Ear Infirmary; 2014-.