"Fatty Acids, Essential" - Books

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Select item 44036681.

StatPearls [Internet].

Treasure Island (FL): StatPearls Publishing; 2026 Jan-.

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Select item 34012942.

Endotext [Internet].

Feingold KR, Adler RA, Ahmed SF, et al., editors.

South Dartmouth (MA): MDText.com, Inc.; 2000-.

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Select item 14589843.

GeneReviews® [Internet].

Adam MP, Bick S, Mirzaa GM, et al., editors.

Seattle (WA): University of Washington, Seattle; 1993-2026.

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Select item 14152804.

Madame Curie Bioscience Database [Internet].

Austin (TX): Landes Bioscience; 2000-2013.

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Select item 24345725.

Fat Detection: Taste, Texture, and Post Ingestive Effects.

Montmayeur JP, le Coutre J, editors.

Boca Raton (FL): CRC Press/Taylor & Francis; 2010.

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Select item 26591826.

Database of Abstracts of Reviews of Effects (DARE): Quality-assessed Reviews [Internet].

York (UK): Centre for Reviews and Dissemination (UK); 1995-.

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Select item 31090427.

Food Components to Enhance Performance: An Evaluation of Potential Performance-Enhancing Food Components for Operational Rations.

Institute of Medicine (US) Committee on Military Nutrition Research; Marriott BM, editor.

Washington (DC): National Academies Press (US); 1994.

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Select item 32530468.

Nutrient Requirements of Laboratory Animals: Fourth Revised Edition, 1995.

National Research Council (US) Subcommittee on Laboratory Animal Nutrition.

Washington (DC): National Academies Press (US); 1995.

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Select item 31723569.

Diet and Health: Implications for Reducing Chronic Disease Risk.

National Research Council (US) Committee on Diet and Health.

Washington (DC): National Academies Press (US); 1989.

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Select item 186024210.

WormBook: The Online Review of C. elegans Biology [Internet].

Pasadena (CA): WormBook; 2005-2018.

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Select item 323143411.

Military Strategies for Sustainment of Nutrition and Immune Function in the Field.

Institute of Medicine (US) Committee on Military Nutrition Research.

Washington (DC): National Academies Press (US); 1999.

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Select item 311711012.

Nutrition and Traumatic Brain Injury: Improving Acute and Subacute Health Outcomes in Military Personnel.

Institute of Medicine (US) Committee on Nutrition, Trauma, and the Brain; Erdman J, Oria M, Pillsbury L, editors.

Washington (DC): National Academies Press (US); 2011.

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Select item 557058413.

Nutrient Requirements of Dairy Cattle: Eighth Revised Edition.

National Academies of Sciences, Engineering, and Medicine; Division on Earth and Life Studies; Board on Agriculture and Natural Resources; Committee on Nutrient Requirements of Dairy Cattle.

Washington (DC): National Academies Press (US); 2021 Aug 30.

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Select item 316037014.

Designing Foods: Animal Product Options in the Marketplace.

National Research Council (US) Committee on Technological Options to Improve the Nutritional Attributes of Animal Products.

Washington (DC): National Academies Press (US); 1988.

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Select item 188138215.

Basic Neurochemistry: Molecular, Cellular and Medical Aspects. 6th edition.

Siegel GJ, Agranoff BW, Albers RW, et al., editors.

Philadelphia: Lippincott-Raven; 1999.

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Select item 447335016.

Guiding Principles for Developing Dietary Reference Intakes Based on Chronic Disease.

National Academies of Sciences, Engineering, and Medicine; Health and Medicine Division; Food and Nutrition Board; Committee on the Development of Guiding Principles for the Inclusion of Chronic Disease Endpoints in Future Dietary Reference Intakes; Oria MP, Kumanyika S, editors.

Washington (DC): National Academies Press (US); 2017 Aug 3.

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Dietary Total Fat Intake and Dietary Polyunsaturated Fatty Acid Intake and Child Growth and Development Outcomes: Systematic Review [Internet].

Jungbauer RM, Stadler DD, Hsu F, et al.

Rockville (MD): Agency for Healthcare Research and Quality (US); 2026 Jan.

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The Heterogeneity of Cancer Metabolism [Internet]. 2nd edition.

Le A, editor.

Cham (CH): Springer; 2021.

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Select item 463899619.

Pharmacological and non-pharmacological interventions for non-respiratory sleep disturbance in children with neurodisabilities: a systematic review.

Beresford B, McDaid C, Parker A, et al.

Southampton (UK): NIHR Journals Library; 2018 Oct. (Health Technology Assessment, No. 22.60.)

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Select item 564816820.

The Role of Seafood Consumption in Child Growth and Development.

National Academies of Sciences, Engineering, and Medicine; Health and Medicine Division; Food and Nutrition Board; Committee on the Role of Seafood Consumption on Child Growth and Development.

Washington (DC): National Academies Press (US); 2024 May 28.

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Figure 3-7

Pathways for interconversion of brain fatty acids. Palmitic acid (16:0) is the main end product of brain fatty acid synthase. It may then be elongated, desaturated and/or β-oxidized to form different long-chain fatty acids. The monoenes (18:1▵⁹, 18:1▵⁷, 24:1▵¹⁵) are the main unsaturated fatty acids formed de novo by ▵⁹ desaturation and chain elongation. As shown, the very-long-chain fatty acids are α-oxidized to form α-hydroxy and odd-numbered fatty acids. The polyunsaturated fatty acids are formed mainly from exogenous dietary fatty acids, such as linoleic (ω6) and α-linolenic (ω3) acids, by chain elongation and desaturation (▵⁵, ▵⁶), as shown. It is doubtful whether there is a ▵⁴ desaturase in brain; the apparent ▵⁴ desaturation is probably effected by first chain elongation (+C₂), then ▵⁶ desaturation in microsomes, followed by peroxisomal β oxidation (C₂), that is, by “retroconversion.” In severe essential fatty acid deficiency, the abnormal polyenes, such as 20:3, ω9, are also biosynthesized de novo.

Brain Lipid Biosynthesis.

Siegel GJ, Agranoff BW, Albers RW, et al., editors. Basic Neurochemistry: Molecular, Cellular and Medical Aspects. 6th edition. Philadelphia: Lippincott-Raven; 1999.
Figure 1.2 Schematic diagram illustrating the role of the metabolism of the essential fatty acids in neuronal signal transduction

Introduction.

MacLean CH, Issa AM, Newberry SJ, et al. Effects of Omega-3 Fatty Acids on Cognitive Function with Aging, Dementia, and Neurological Diseases. Rockville (MD): Agency for Healthcare Research and Quality (US); 2005 Feb.
FIGURE 2.6

Chain elongation and desaturation pathways of the parent essential fatty acids ALA and LA, and of stearic and palmitic acids. Abbreviations: ALA, alpha-linolenic acid; EPA, eicosapentaenoic acid; DHA, docosahexaenoic acid; GLA, gamma-linolenic acid; DGLA, dihomo-gamma-linolenic acid; AA, arachidonic acid; MA, Mead acid; FADS1, fatty acid desaturase 1 (delta-5 desaturase); FADS2, fatty acid desaturase 2 (delta-6 desaturase); SCD, steroyl-CoA desaturase (delta-9 desaturase).

Pathophysiology and Evolutionary Aspects of Dietary Fats and Long-Chain Polyunsaturated Fatty Acids across the Life Cycle.

Montmayeur JP, le Coutre J, editors. Fat Detection: Taste, Texture, and Post Ingestive Effects. Boca Raton (FL): CRC Press/Taylor & Francis; 2010.
FIGURE 18.1

Schematic of the neural regulation of food intake. Hypothalamus, in concert with brain stem and corticolimbic structures receives and integrates hormonal and metabolic signals from the periphery to regulate energy homeostasis. At the cellular level, acetyl-CoA is carboxylated to malonyl-CoA by the enzyme acetyl-CoA carboxylase in the cytoplasm to eventually synthesize fatty acids. A decrease in AMPK activity results in reduced food intake. Anorectic hormones leptin and insulin inhibit AMPK activity. Malonyl-CoA inhibits oxidation of fatty acids by inhibiting CPT-1. Hypothalamic inhibition of CPT-1 reduces food intake. Inhibition of FAS also reduces food intake. Peripheral signals shown in the figure include both anorexigenic and orexigenic signals and, for the sake of simplicity, only effects of leptin and insulin are depicted at the cellular level.

Control of Fatty Acid Intake and the Role of Essential Fatty Acids in Cognitive Function and Neurological Disorders.

Montmayeur JP, le Coutre J, editors. Fat Detection: Taste, Texture, and Post Ingestive Effects. Boca Raton (FL): CRC Press/Taylor & Francis; 2010.