"Endothelins" - Books

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Select item 44036681.

StatPearls [Internet].

Treasure Island (FL): StatPearls Publishing; 2026 Jan-.

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Select item 25451962.

The Endothelium: Part 1: Multiple Functions of the Endothelial Cells—Focus on Endothelium-Derived Vasoactive Mediators.

Félétou M.

San Rafael (CA): Morgan & Claypool Life Sciences; 2011.

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Select item 14152803.

Madame Curie Bioscience Database [Internet].

Austin (TX): Landes Bioscience; 2000-2013.

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Select item 26591824.

Database of Abstracts of Reviews of Effects (DARE): Quality-assessed Reviews [Internet].

York (UK): Centre for Reviews and Dissemination (UK); 1995-.

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Select item 48538165.

LiverTox®: Clinical and Research Information on Drug-Induced Liver Injury [Internet].

Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases; 2012-.

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Select item 14563906.

Endocrinology: An Integrated Approach.

Nussey S, Whitehead S.

Oxford: BIOS Scientific Publishers; 2001.

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Select item 34012947.

Endotext [Internet].

Feingold KR, Adler RA, Ahmed SF, et al., editors.

South Dartmouth (MA): MDText.com, Inc.; 2000-.

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Select item 42353808.

Drugs for Pulmonary Arterial Hypertension: Comparative Efficacy, Safety, and Cost-Effectiveness [Internet].

Tran K, Coyle K, Jabr MF, et al.

Ottawa (ON): Canadian Agency for Drugs and Technologies in Health; 2015 Mar.

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Select item 15027929.

Molecular Imaging and Contrast Agent Database (MICAD) [Internet].

Bethesda (MD): National Center for Biotechnology Information (US); 2004-2013.

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Select item 421658410.

Macitentan (Opsumit): For Long-Term Treatment of Pulmonary Arterial Hypertension [Internet].

Ottawa (ON): Canadian Agency for Drugs and Technologies in Health; 2015 Jul.

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Select item 410317411.

Brain Neurotrauma: Molecular, Neuropsychological, and Rehabilitation Aspects.

Kobeissy FH, editor.

Boca Raton (FL): CRC Press/Taylor & Francis; 2015.

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Select item 466662212.

Mechanisms of Vascular Disease: A Reference Book for Vascular Specialists [Internet].

Fitridge R, Thompson M, editors.

Adelaide (AU): University of Adelaide Press; 2011.

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Select item 454429013.

Etiology and Morphogenesis of Congenital Heart Disease: From Gene Function and Cellular Interaction to Morphology [Internet].

Nakanishi T, Markwald RR, Baldwin HS, et al., editors.

Tokyo: Springer; 2016.

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Select item 475919614.

Pharmacoeconomic Review Report: Riociguat (Adempas) [Internet].

Ottawa (ON): Canadian Agency for Drugs and Technologies in Health; 2015 Dec.

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Select item 474030815.

Clinical Review Report: Riociguat (Adempas) [Internet].

Ottawa (ON): Canadian Agency for Drugs and Technologies in Health; 2015 Dec.

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Select item 235805216.

Probe Reports from the NIH Molecular Libraries Program [Internet].

Bethesda (MD): National Center for Biotechnology Information (US); 2010-.

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Select item 157694217.

Mechanosensitivity in Cells and Tissues.

Kamkin A, Kiseleva I, editors.

Moscow: Academia; 2005.

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Select item 243184818.

Vascular Biology of the Placenta.

Wang Y, Zhao S.

San Rafael (CA): Morgan & Claypool Life Sciences; 2010.

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Select item 446506419.

Autoimmunity: From Bench to Bedside [Internet].

Anaya JM, Shoenfeld Y, Rojas-Villarraga A, et al., editors.

Bogota (Colombia): El Rosario University Press; 2013 Jul 18.

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Select item 537033020.

Selected Immune Disorders and Disability.

National Academies of Sciences, Engineering, and Medicine; Health and Medicine Division; Board on Health Care Services; Committee on Selected Immune Disorders and Disability.

Washington (DC): National Academies Press (US); 2022 May 24.

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Supplemental Content

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FIGURE 33The endothelins. ET: endothelin; ECE: endothelin-converting enzyme.

Endothelium-Dependent Regulation of Vascular Tone.

Félétou M. The Endothelium: Part 1: Multiple Functions of the Endothelial Cells—Focus on Endothelium-Derived Vasoactive Mediators. San Rafael (CA): Morgan & Claypool Life Sciences; 2011.
FIGURE 4.7

Schematic showing factors in bone (A) and receptors/channels expressed by nociceptors that innervate the skeleton (B) that drive bone cancer pain. A variety of cells (tumor cells, and stomal cells including inflammatory/immune cells, and osteoclasts) drive bone cancer pain (A). Nociceptors that innervate the bone use several different types of receptors to detect and transmit noxious stimuli that are produced by cancer cells, tumor-associated immune cells, or other aspects of the tumor microenvironment. There are multiple factors that may contribute to the pain associated with cancer (B). The transient receptor potential vanilloid receptor-1 (TRPV1) and acid-sensing ion channels (ASICs) detect extracellular protons produced by tumor-induced tissue damage or abnormal osteoclast mediated bone resorption. Tumor cells and associated inflammatory (immune) cells produce a variety of chemical mediators including prostaglandins (PGE2), nerve growth factor (NGF), endothelins, bradykinin, and extracellular ATP. Several of these proinflammatory mediators have receptors on peripheral terminals and can directly activate or sensitize nociceptors. NGF and its cognate receptor TrkA may serve as a master regulator of bone cancer pain by modulating the sensitivity or increasing the expression of several receptors and ion channels contributing to increased excitability of nociceptors in the vicinity of the tumor.

Cancer Pain: From the Development of Mouse Models to Human Clinical Trials.

Kruger L, Light AR, editors. Translational Pain Research: From Mouse to Man. Boca Raton (FL): CRC Press/Taylor & Francis; 2010.