"Baclofen" - Books

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Select item 14589841.

GeneReviews® [Internet].

Adam MP, Bick S, Mirzaa GM, et al., editors.

Seattle (WA): University of Washington, Seattle; 1993-2026.

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Select item 44036682.

StatPearls [Internet].

Treasure Island (FL): StatPearls Publishing; 2026 Jan-.

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Select item 55328163.

Pharmacotherapy for Adults With Alcohol Use Disorder in Outpatient Settings: Systematic Review [Internet].

McPheeters M, O’Connor EA, Riley S, et al.

Rockville (MD): Agency for Healthcare Research and Quality (US); 2023 Nov. (Comparative Effectiveness Review, No. 262.)

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Select item 50340964.

Compounded Topical Pain Creams: Review of Select Ingredients for Safety, Effectiveness, and Use.

National Academies of Sciences, Engineering, and Medicine; Health and Medicine Division; Board on Health Sciences Policy; Committee on the Assessment of the Available Scientific Data Regarding the Safety and Effectiveness of Ingredients Used in Compounded Topical Pain Creams; Jackson LM, Schwinn DA, editors.

Washington (DC): National Academies Press (US); 2020 May 13.

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Select item 48538165.

LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet].

Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases; 2012-.

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Select item 31078666.

Pharmacotherapy for Adults With Alcohol-Use Disorders in Outpatient Settings [Internet].

Jonas DE, Amick HR, Feltner C, et al.

Rockville (MD): Agency for Healthcare Research and Quality (US); 2014 May. (Comparative Effectiveness Reviews, No. 134.)

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Select item 26591827.

Database of Abstracts of Reviews of Effects (DARE): Quality-assessed Reviews [Internet].

York (UK): Centre for Reviews and Dissemination (UK); 1995-.

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Select item 56264348.

Evidence reviews for interventions for spasticity: Stroke rehabilitation in adults (update): Evidence review P.

London: National Institute for Health and Care Excellence (NICE); 2023 Oct. (NICE Guideline, No. 236.)

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Select item 47089729.

Pharmacotherapy for Stimulant Use Disorders: A Systematic Review [Internet].

Chan B, Kondo K, Ayers C, et al.

Washington (DC): Department of Veterans Affairs (US); 2018 Aug.

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Select item 437649810.

Cerebral palsy in under 25s: assessment and management.

National Guideline Alliance (UK).

London: National Institute for Health and Care Excellence (NICE); 2017 Jan. (NICE Guideline, No. 62.)

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Select item 547414211.

Evidence review for pharmacologicalmanagement of spasticity: Multiple sclerosis in adults: management: Evidence review F.

London: National Institute for Health and Care Excellence (NICE); 2022 Jun. (NICE Guideline, No. 220.)

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Select item 529998612.

Management of abnormal muscle tone: neurosurgical procedures to reduce spasticity: Cerebral palsy in adults: Evidence review A2.

National Guideline Alliance (UK).

London: National Institute for Health and Care Excellence (NICE); 2019 Jan. (NICE Guideline, No. 119.)

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Select item 456563613.

RTI Press Research Brief [Internet].

Research Triangle Park (NC): RTI Press; 2014-.

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Select item 238715614.

Jasper's Basic Mechanisms of the Epilepsies [Internet]. 4th edition.

Noebels JL, Avoli M, Rogawski MA, et al., editors.

Bethesda (MD): National Center for Biotechnology Information (US); 2012.

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Select item 291254815.

Alcohol-Use Disorders: Diagnosis, Assessment and Management of Harmful Drinking and Alcohol Dependence.

National Collaborating Centre for Mental Health (UK).

Leicester (UK): British Psychological Society (UK); 2011. (NICE Clinical Guidelines, No. 115.)

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Select item 475976416.

Clinical Review Report: abobotulinumtoxinA (Dysport Therapeutic): (Ipsen Biopharmaceuticals Canada Inc.): Indication: For the symptomatic treatment of lower-limb spasticity in pediatric patients 2 years of age and older [Internet].

Ottawa (ON): Canadian Agency for Drugs and Technologies in Health; 2018 Aug.

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Select item 443564417.

Systematic review of interventions for treating or preventing antipsychotic-induced tardive dyskinesia.

Bergman H, Walker DM, Nikolakopoulou A, et al.

Southampton (UK): NIHR Journals Library; 2017 Aug. (Health Technology Assessment, No. 21.43.)

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Select item 419434818.

Clinical effectiveness and patient perspectives of different treatment strategies for tics in children and adolescents with Tourette syndrome: a systematic review and qualitative analysis.

Hollis C, Pennant M, Cuenca J, et al.

Southampton (UK): NIHR Journals Library; 2016 Jan. (Health Technology Assessment, No. 20.4.)

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Select item 577042019.

Veterans, Prescription Opioids and Benzodiazepines, and Mortality, 2007–2019: Three Target Trial Emulations.

National Academies of Sciences, Engineering, and Medicine; Health and Medicine Division; Board on Population Health and Public Health Practice; Committee on Evaluating the Effects of Opioids and Benzodiazepines on All-Cause Mortality in Veterans; Doebler DA, Strom BL, editors.

Washington (DC): National Academies Press (US); 2025 Mar 27.

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Select item 467132020.

Clinical Review Report: AbobotulinumtoxinA (Dysport Therapeutic): (Ipsen Biopharmaceuticals Canada, Inc.): Indication: For the symptomatic treatment of focal spasticity affecting the upper limbs in adults [Internet].

Ottawa (ON): Canadian Agency for Drugs and Technologies in Health; 2017 Nov.

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Supplemental Content

Images search in Bookshelf

Figure 7Adverse events after implantation of intrathecal baclofen pump (follow-up range 1 to 5 years)

ITB: intrathecal baclofen

Management of abnormal muscle tone: neurosurgical procedures to reduce spasticity: Cerebral palsy in adults: Evidence review A2.

National Guideline Alliance (UK). Management of abnormal muscle tone: neurosurgical procedures to reduce spasticity: Cerebral palsy in adults: Evidence review A2. London: National Institute for Health and Care Excellence (NICE); 2019 Jan.
Figure E-60Baclofen versus placebo: Nausea by risk-of-bias rating

Notes: Garbutt 2021a dose is 30 mg; Garbutt 2021b dose is 90 mg; Morley, 2014a dose is 30 mg; Morley, 2014b dose is 60 mg; Müller, 2015¹¹⁵ reported GI symptoms as 1 of 28 in the baclofen arms versus 3 of 28 in the placebo arm.
CI = confidence interval; Med = medium; mg = milligram; n/N = sample size.

Meta-Analyses.

McPheeters M, O’Connor EA, Riley S, et al. Pharmacotherapy for Adults With Alcohol Use Disorder in Outpatient Settings: Systematic Review [Internet]. Rockville (MD): Agency for Healthcare Research and Quality (US); 2023 Nov.
Figure 10Retention in studies that compared baclofen vs placebo for cocaine use disorder

Methods.

Chan B, Kondo K, Ayers C, et al. Pharmacotherapy for Stimulant Use Disorders: A Systematic Review [Internet]. Washington (DC): Department of Veterans Affairs (US); 2018 Aug.
Figure E-54Baclofen versus placebo: Diarrhea by risk-of-bias rating

CI = confidence interval; Med = medium; n/N = sample size.

Meta-Analyses.

McPheeters M, O’Connor EA, Riley S, et al. Pharmacotherapy for Adults With Alcohol Use Disorder in Outpatient Settings: Systematic Review [Internet]. Rockville (MD): Agency for Healthcare Research and Quality (US); 2023 Nov.