"Antibodies, Neutralizing" - Books

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Select item 44036681.

StatPearls [Internet].

Treasure Island (FL): StatPearls Publishing; 2025 Jan-.

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Select item 23639742.

Human Herpesviruses: Biology, Therapy, and Immunoprophylaxis.

Arvin A, Campadelli-Fiume G, Mocarski E, et al., editors.

Cambridge: Cambridge University Press; 2007.

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Select item 14152803.

Madame Curie Bioscience Database [Internet].

Austin (TX): Landes Bioscience; 2000-2013.

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Select item 15816864.

Medical Microbiology. 4th edition.

Baron S, editor.

Galveston (TX): University of Texas Medical Branch at Galveston; 1996.

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Select item 16686905.

Holland-Frei Cancer Medicine. 6th edition.

Kufe DW, Pollock RE, Weichselbaum RR, et al., editors.

Hamilton (ON): BC Decker; 2003.

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Select item 16868406.

Retroviruses.

Coffin JM, Hughes SH, Varmus HE, editors.

Cold Spring Harbor (NY): Cold Spring Harbor Laboratory Press; 1997.

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Select item 14003627.

Hepatitis C Viruses: Genomes and Molecular Biology.

Tan SL, editor.

Norfolk (UK): Horizon Bioscience; 2006.

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Select item 16541068.

Immunobiology: The Immune System in Health and Disease. 5th edition.

Janeway CA Jr, Travers P, Walport M, et al.

New York: Garland Science; 2001.

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Select item 34012949.

Endotext [Internet].

Feingold KR, Adler RA, Ahmed SF, et al., editors.

South Dartmouth (MA): MDText.com, Inc.; 2000-.

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Select item 565021610.

Fidanacogene Elaparvovec (Beqvez): CADTH Reimbursement Review: Therapeutic area: Hemophilia B [Internet].

Ottawa (ON): Canadian Agency for Drugs and Technologies in Health; 2024 Jun.

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Select item 407316011.

Malaria and Some Polyomaviruses (SV40, BK, JC, and Merkel Cell Viruses).

IARC Working Group on the Evaluation of Carcinogenic Risks to Humans.

Lyon (FR): International Agency for Research on Cancer; 2013. (IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, No. 104.)

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Select item 540176812.

Streptococcus pyogenes: Basic Biology to Clinical Manifestations [Internet]. 2nd edition.

Ferretti JJ, Stevens DL, Fischetti VA, editors.

Oklahoma City (OK): University of Oklahoma Health Sciences Center; 2022 Oct 8.

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Select item 409064613.

Primary End-points for Prophylactic HPV Vaccine Trials.

IARC HPV Working Group.

Lyon (FR): International Agency for Research on Cancer; 2014. (IARC Working Group Reports, No. 7.)

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Select item 324851414.

Vaccines for the 21st Century: A Tool for Decisionmaking.

Institute of Medicine (US) Committee to Study Priorities for Vaccine Development; Stratton KR, Durch JS, Lawrence RS, editors.

Washington (DC): National Academies Press (US); 2000.

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Select item 136719615.

Immunology and Evolution of Infectious Disease.

Frank SA.

Princeton (NJ): Princeton University Press; 2002.

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Select item 326098016.

Contraceptive Research and Development: Looking to the Future.

Institute of Medicine (US) Committee on Contraceptive Research and Development; Harrison PF, Rosenfield A, editors.

Washington (DC): National Academies Press (US); 1996.

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Select item 317101417.

New Vaccine Development Establishing Priorities: Volume II: Diseases of Importance in Developing Countries.

Institute of Medicine (US) Committee on Issues and Priorities for New Vaccine Development.

Washington (DC): National Academies Press (US); 1986.

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Select item 576526218.

Principles and Practice of Emergency Research Response [Internet].

Sorenson RA, Higgs ES, Fallah MP, et al., editors.

Cham (CH): Springer; 2024.

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Select item 530829219.

Vaccine Research and Development to Advance Pandemic and Seasonal Influenza Preparedness and Response: Lessons from COVID-19.

National Academy of Medicine; National Academies of Sciences, Engineering, and Medicine; Health and Medicine Division; Board on Global Health; Committee on Vaccine Research and Development Recommendations for Advancing Pandemic and Seasonal Influenza Preparedness and Response; Soltani H, Subbarao K, Bond E, editors.

Washington (DC): National Academies Press (US); 2021 Nov 17.

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Select item 420372020.

Streptococcus pyogenes : Basic Biology to Clinical Manifestations [Internet].

Ferretti JJ, Stevens DL, Fischetti VA, editors.

Oklahoma City (OK): University of Oklahoma Health Sciences Center; 2016-.

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Supplemental Content

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Figure 1.24Antibodies can participate in host defense in three main ways

The left panels show antibodies binding to and neutralizing a bacterial toxin, thus preventing it from interacting with host cells and causing pathology. Unbound toxin can react with receptors on the host cell, whereas the toxin:antibody complex cannot. Antibodies also neutralize complete virus particles and bacterial cells by binding to them and inactivating them. The antigen:antibody complex is eventually scavenged and degraded by macrophages. Antibodies coating an antigen render it recognizable as foreign by phagocytes (macrophages and neutrophils), which then ingest and destroy it; this is called opsonization. The middle panels show opsonization and phagocytosis of a bacterial cell. The right panels show activation of the complement system by antibodies coating a bacterial cell. Bound antibodies form a receptor for the first protein of the complement system, which eventually forms a protein complex on the surface of the bacterium that, in some cases, can kill the bacterium directly. More generally, complement coating favors the uptake and destruction of the bacterium by phagocytes. Thus, antibodies target pathogens and their toxic products for disposal by phagocytes.

The recognition and effector mechanisms of adaptive immunity.

Janeway CA Jr, Travers P, Walport M, et al. Immunobiology: The Immune System in Health and Disease. 5th edition. New York: Garland Science; 2001.
Fig. 53.6

Cumulative incidence of nasopharyngeal carcinoma in persons testing positive or negative for either IgA anti-Epstein– Barr virus viral capsid or neutralizing anti-Epstein–Barr virus DNase antibodies. Reproduced from Chien et al., 2001 with permission from the Massachusetts Medical Society.

The epidemiology of EBV and its association with malignant disease.

Arvin A, Campadelli-Fiume G, Mocarski E, et al., editors. Human Herpesviruses: Biology, Therapy, and Immunoprophylaxis. Cambridge: Cambridge University Press; 2007.
Fig. 3

An overview of the sources used to identify agents for prioritization in the ACTIV master protocols. The clinical therapeutics fall into four categories (antivirals, immunomodulators, supportive therapies, and neutralizing antibodies). The activities of the prioritization team also included refining the process and criteria, scoring the candidates, and assessing logistical needs. (NIH 2020d)

ACTIV: A U.S. Public-Private Partnership Responds to COVID-19.

Sorenson RA, Higgs ES, Fallah MP, et al., editors. Principles and Practice of Emergency Research Response [Internet]. Cham (CH): Springer; 2024.
FIGURE 4.8

(A) Growth of lymphatic endothelial cells could be blocked with VEGFR3 neutralizing antibodies and rescued with VEGF-C therapy. (B) An experimental reduction in interstitial fluid (ISF) flow led to a decrease in growth of lymphatic endothelial cells. Lymphatic endothelial cell (LEC) density was determined from immunostained cryosections of mouse tail skin. Redrawn after Goldman et al. (2007) [337].

Regulation: Mechanical Factors.

Adair TH, Montani JP. Angiogenesis. San Rafael (CA): Morgan & Claypool Life Sciences; 2010.