Table G-6Behavioral counseling interventions for pregnant women compared with usual care

Domains Pertaining to Strength of EvidenceMagnitude of EffectStrength of Evidence
Number of Studies; Number of SubjectsRisk of Bias; Design/ QualityConsistencyDirectnessPrecisionSummary Effect Size (95%CI)High, Moderate, Low, Insufficient
Alcohol use, mean change in drinks per week
1; 250Medium;
RCT/Fair
NA, single studyIndirectImpreciseDifference between groups was not statistically significant (-0.3 vs. -0.4, p=NS, excluding patients who maintained abstinence through the end).Low
Heavy drinking episodes
0; 0NANANANANAInsufficient
Recommended drinking limits achieved
0; 0NANANANANAInsufficient
Followup with referrals
0; 0NANANANANAInsufficient
Abstinence
1; 250Medium;
RCT/Fair
NA, single studyIndirectImpreciseFor the overall sample, data were not reportedaInsufficienta
a

For the subgroup of subjects who were abstinent prior to assessment, those who received the intervention maintained higher rates of abstinence than those in the control group (86% vs. 72%, p=0.04, low strength of evidence).

Abbreviations: CI = confidence interval; NA = not applicable; NS = not significant; RCT = randomized controlled trial.

From: Appendix G, Strength of Evidence Tables

Cover of Screening, Behavioral Counseling, and Referral in Primary Care To Reduce Alcohol Misuse
Screening, Behavioral Counseling, and Referral in Primary Care To Reduce Alcohol Misuse [Internet].
Comparative Effectiveness Reviews, No. 64.
Jonas DE, Garbutt JC, Brown JM, et al.

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