Figure 11.14. Attachment of actin filaments to adherens junctions.

Figure 11.14Attachment of actin filaments to adherens junctions

Cell-cell contacts at adherens junctions are mediated by cadherins, which serve as sites of attachment of actin bundles. In sheets of epithelial cells, these junctions form a continuous belt of actin filaments around each cell. The cadherins are transmembrane proteins that bind β-catenin to their cytoplasmic domains. β-catenin interacts with α-catenin, which serves as a link to actin filaments.

From: Structure and Organization of Actin Filaments

Cover of The Cell
The Cell: A Molecular Approach. 2nd edition.
Cooper GM.
Sunderland (MA): Sinauer Associates; 2000.
Copyright © 2000, Geoffrey M Cooper.

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