Figure 11.10. Structure of spectrin.

Figure 11.10Structure of spectrin

Spectrin is a tetramer consisting of two α and two β chains. Each β chain has a single actin-binding domain (ABD) at its amino terminus. Both α and β chains contain multiple repeats of α-helical spacer domains, which separate the two actin-binding domains of the tetramer. The α chain has two Ca2+ binding domains at its carboxy terminus.

From: Structure and Organization of Actin Filaments

Cover of The Cell
The Cell: A Molecular Approach. 2nd edition.
Cooper GM.
Sunderland (MA): Sinauer Associates; 2000.
Copyright © 2000, Geoffrey M Cooper.

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