Table 51Indirect outcomes in RCT on rFVIIa use in prostatectomy

ArticleStudy Design rFVIIa userFVIIa indication and dose (μg/kg)Sample sizeMean age (SD)RBC transfusion (SD)OR time (minutes) (SD)
rFVIIaUsual carerFVIIaUsual carerFVIIaUsual careSigrFVIIaUsual careSig
Friederich 2003141RCT
Prophylaxis
20
40
8
16
1261 (8.9)
64 (8.5)
63 (8.3)0.6 (0.3)
0 (0)
1.5 (0.4)p=.057
p=.0003
126 (21)
120 (15)
180 (16)p=.034
p=.014

Sig=tests of statistical significance between the usual care and rFVIIa group(s). The p-values presented are those reported by the individual studies.

From: Results

Cover of Comparative Effectiveness of In-Hospital Use of Recombinant Factor VIIa for Off-Label Indications vs. Usual Care
Comparative Effectiveness of In-Hospital Use of Recombinant Factor VIIa for Off-Label Indications vs. Usual Care [Internet].
Comparative Effectiveness Reviews, No. 21.
Yank V, Tuohy CV, Logan AC, et al.

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