Table 12Clinical indication and study type of included studies

Clinical IndicationNumber of studies N (percent)
Total N=74RCT N=24Comparative observational N=31Non-comparative observational N=19
Key Question 1 Indications
 Other liver disease54 (17)1 (3)NC
 Obstetrics/gynecology30 (0)3 (10)NC
 Hematology/oncology32 (8)1 (3)NC
 Other surgery64 (17)2 (7)NC
Key Questions 2-4 Indications
 Intracranial hemorrhage114 (17)4 (13)3 (16)
 Body trauma111 (4)5 (16)2 (11)
 Brain trauma41 (4)2 (7)1 (5)
 Liver transplantation84 (17)4 (13)0
 Adult cardiac surgery192 (8)6 (19)11 (58)
 Pediatric cardiac surgery41 (4)3 (10)0
 Prostatectomy11 (4)0 (0)0

Note: Data from non-comparative observational studies were used to analyze harms associated with rFVIIa use.

NC=not collected

From: Results

Cover of Comparative Effectiveness of In-Hospital Use of Recombinant Factor VIIa for Off-Label Indications vs. Usual Care
Comparative Effectiveness of In-Hospital Use of Recombinant Factor VIIa for Off-Label Indications vs. Usual Care [Internet].
Comparative Effectiveness Reviews, No. 21.
Yank V, Tuohy CV, Logan AC, et al.

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